Genomic history of the Golden Horde
PNAS Science Sessions
Genomics of the Golden Horde Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Ayken Askapuli explains genomic insights into the ancestors and descendants of the Golden Horde. In this episode, we cover: •[00:00] Introduction. •[00:56] Population...
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Concrete and carbon uptake
PNAS Science Sessions
How much carbon dioxide concrete can absorb Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Hessam Azarijafari explains the extent to which concrete can absorb carbon dioxide over its lifecycle. In this episode, we cover: •[00:00] Introduction....
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Reconstructing extinct species' sense of smell
PNAS Science Sessions
Determining how well extinct animals could smell Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Quentin Martinez describes a reconstruction of olfactory capabilities in extinct mammals. In this episode, we cover: •[00:00] Introduction...
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The hidden costs of AI
PNAS Science Sessions
Hidden sustainability costs of AI Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, researchers describe the sustainability impact of AI data centers. In this episode, we cover: •[00:00] Introduction •[01:20] Bronis de Supinski describes how the...
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How mosquitoes time their bites
PNAS Science Sessions
Molecular regulation of mosquito biting timing Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Laura Duvall introduces a potential pathway for disrupting the biting behavior of mosquitoes. In this episode, we cover: •[00:00] Introduction...
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Impact of flu vaccines on hospital burden
PNAS Science Sessions
How well flu vaccines protect public health Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Lauren Meyers explains what the 2022-2023 influenza season taught us about the effectiveness of flu vaccines. In this episode, we cover: •[00:00]...
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Secrets of Earth’s climate in six-million-year-old ice
PNAS Science Sessions
Air quality and pet health Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Sarah Shackleton shares climate lessons learned from 6 million-year-old ice. In this episode, we cover: •[00:00] Introduction •[01:02] Paleoclimate and ice scientist...
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China, ascendent
PNAS Science Sessions
China’s science leadership Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, James Evans explains how and why China's leadership in global science is rising. In this episode, we cover: •[00:00] Introduction •[00:56] Social and complex systems...
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Genetic history of dog domestication
PNAS Science Sessions
Genetic history of dog domestication Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, researchers explore the impact of domestication on dog genetics and behavior. In this episode, we cover: •[00:00] Introduction •[01:00] Greger Larson explains...
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Air pollution and pet health
PNAS Science Sessions
Air quality and pet health Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us. In this episode, Stephen Jarvis explores the health impacts of poor air quality on pets. In this episode, we cover: •[00:00] Introduction •[00:51] Environmental economist Stephen Jarvis...
info_outlineImplications of a mutation in modern humans
Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us.
In this episode, Xiangchun Ju and Svante Pääbo explore the evolutionary implications of a mutation that separates modern humans from ancestral hominins.
In this episode, we cover:
•[00:00]
•[01:22] Neurobiologist Xiangchun Ju introduces the enzyme adenylosuccinate lyase, or ADSL, and its role in the synthesis of purine.
•[02:09] Evolutionary anthropologist Svante Pääbo talks about the discovery of the A429V mutation, which is present in modern humans but not Neanderthals or Denisovans.
•[03:38] Ju and Pääbo talk about the methods to humanize mice in order to study the evolutionary importance of the A429V mutation.
•[05:04] They explain the results of the behavioral studies of the humanized mice.
•[06:27] Pääbo explores the takeaways from the study.
•[08:05] He contextualizes the study alongside other studies of modern human development.
•[09:17] Pääbo and Ju list the caveats and limitations of the study.
•[10:14] Conclusion.
About Our Guests:
Xiangchun Ju
Postdoctoral scholar
Okinawa Institute of Science and Technology
Svante Pääbo
Director
Max Planck Institute for Evolutionary Anthropology
View related content here: https://www.pnas.org/doi/10.1073/pnas.2508540122
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