Multi-Organ Transplant
PodcastDX
This week we will discuss Multi-Organ transplants with Zachary Colton. Zach is 35 years old and recently underwent a successful 5 organ multivisceral intestinal transplant surgery at the Toronto General Hospital in his home country of Canada. The organs he received were: stomach, small intestine, colon, liver, and pancreas. In 1954, . Liver, heart and pancreas transplants were successfully performed by the late 1960s, while lung and intestinal organ transplant procedures were begun in the 1980s. From the mid-1950s through the early 1970s, individual transplant hospitals...
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Ectoparasites
PodcastDX
This week we will discuss Ectoparasites. The CDC says: "Although the term ectoparasites can broadly include blood-sucking arthropods such as mosquitoes (because they are dependent on a blood meal from a human host for their survival), this term is generally used more narrowly to refer to organisms such as ticks, fleas, lice, and mites that attach or burrow into the skin and remain there for relatively long periods of time (e.g., weeks to months). Arthropods are important in causing diseases in their own right, but are even more important as vectors, or transmitters, of many different...
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Pasteurization For Your Health
PodcastDX
Over 200 years ago Louis Pasteur was born in Dole, France. Among Pasteur's major contributions and their benefit to society, the most important is the heat treatment of foods and beverages to reduce spoilage and eliminate pathogens for consumers. Probably the greatest achievement of Pasteur was the process that bears the name of this famous scientist who perfected the technique: pasteurization. For liquids, this process does not involve boiling the product to sterility but simply applying just enough heat (ie, par-boiling) to 50–60°C for a specified period to reduce spoilage microbes and...
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Spontaneous Pneumothorax with Jack
PodcastDX
In this episode we are talking again with our audio editor Jack Scaro. The topic again is: spontaneous pneumothorax, or collapsed lung. Spontaneous pneumothorax is an abnormal condition of the lung characterized by the collection of gas in the pleural space between the lungs and the chest wall. This condition occurs without an obvious etiology and can be classified as either primary or secondary. Patients may present with symptoms such as tachycardia and dyspnea. The diagnosis is based on clinical suspicion and can be confirmed with imaging. Jack had this condition which surprised...
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Bile acid malabsorption (BAM) part 2
PodcastDX
This week we will continue our coverage of Bile acid malabsorption (BAM), a . It’s a common cause of . When bile acids aren’t properly absorbed in your intestines, they build up, upsetting the chemical balance inside. Excess bile acids trigger your to secrete extra water, leading to watery stools. This week we will continue our coverage of Bile acid malabsorption (BAM), a . It’s a common cause of . When bile acids aren’t properly absorbed in your intestines, they build up, upsetting the chemical balance inside. Excess bile acids trigger...
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Bile Acid Malabsorption
PodcastDX
This week we will discuss Bile acid malabsorption (BAM), a . It’s a common cause of . When bile acids aren’t properly absorbed in your intestines, they build up, upsetting the chemical balance inside. Excess bile acids trigger your to secrete extra water, leading to watery stools. What are bile acids? Bile is a substance your makes while filtering your blood. Your liver sorts waste products, such as toxins, dead blood cells and excess cholesterol into bile. Bile acids come from synthesizing these products together. The different acids in bile help...
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Veteran's Hesitancy to Healthcare
PodcastDX
This week we will discuss a Veteran's hesitancy to receive healthcare at the government hospital system known as Veterans Administration or "VA". Although many veterans may share the concern over receiving care through a government agency due to the medical care they got while in training or active duty; i.e. sucrettes and tylenol being the standard of care when Jean Marie and I were in training. Our guest, Mark Frerichs, has different reasons to question the quality of care. Mark, a Navy veteran who continued working as a contractor post-war in Afghanistan. It was during his work...
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Adrenal Insufficiency
PodcastDX
In this episode we discuss adrenal insufficiency You can have either primary, secondary, or tertiary adrenal insufficiency. Primary adrenal insufficiency is also called Addison’s disease. When you have this type, your adrenal glands are damaged and can’t make the cortisol you need. They also might not make enough aldosterone. Secondary adrenal insufficiency is more common than Addison’s disease. The condition happens because of a problem with your pituitary gland, a pea-sized bulge at the base of your . It makes a hormone called adrenocorticotropin (ACTH). This is the...
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Heart Attack on a Train
PodcastDX
Have you ever wondered "what would happen if you or a family member had a medical emergency while using public transportation" Today we feature Bill H. who had a cardiac event after boarding a Chicago Metra train and the two bystanders that weren't about to let these be his LAST train ride! can help save lives during sudden cardiac arrest. However, even after training, remembering the steps to use an AED the right way can be difficult. In order to help keep your skills sharp, we've created a quick step-by-step guide that you can print up and place on your refrigerator, in...
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EDS and Gastroparesis
PodcastDX
This week we are speaking with Dani, AKA, Stoned Zebra. It took almost 7 years of her health declining after giving birth, until she finally received her EDS diagnosis. She was initially misdiagnosed with Lupus, Fibromyalgia, Neuropathy, or chronic pain syndrome. Her gastroparesis, symptoms (bloating, nausea, early satiety, severe constipation, weight loss, dehydration, belching, belly pain) began July 2022, and after a ton of aggressive testing, she was diagnosed in May 2023. EDS just tacks on chronic pain, joint instability and other comorbidities like POTS, MCAS, and OH that...
info_outlineOur guest today is Chelsea Weaver, a 31-year-old living in Tennessee. She has a beautiful little girl that is just over 2 years old, a wonderful husband, and they all live on a quiet farm property. Before coming down with COVID, she was a surgical technologist. She used to assist in open heart surgery as well as some other specialties but hasn't been able to function in her career for about two years now. Unfortunately, her COVID symptoms have morphed into Long COVID (specifically POTs or Postural Orthostatic Tachycardia Syndrome.)
While the global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections has slowed, many people suffer long-lasting symptoms, a condition known as post-acute sequelae of COVID 2019 (COVID-19) (PASC), or long COVID. Even though PASC is not widely described, it is most commonly defined as COVID-19 symptoms that continue longer than 30 days.
PASC can manifest as a wide range of symptoms, many exhibiting autonomic characteristics. An autonomic nervous system illness, postural orthostatic tachycardia syndrome (POTS), strongly connected with a prior viral infection, is the most prevalent autonomic diagnosis correlated with PASC.
The most prevalent symptoms were brain fog, exhaustion, shortness of breath with exercise, headache, palpitations, body pains, tachycardia, and lightheadedness, consistent with previous research that found many of the same symptoms in individuals with PASC.
A COMPASS-31 score of above 20 was found in 67% of PASC patients, indicating autonomic dysfunction with moderate to severe. The COMPASS-31 consists of 31 questions that fall into 6 domains of dysautonomia: orthostatic intolerance (4 items), vasomotor dysfunction (3 items), secretomotor dysfunction (4 items), GI dysfunction (12 items; includes gastroparesis, constipation, and diarrhea), urinary dysfunction (3 items), and pupillomotor dysfunction (5 items). An answer was scored as zero when it was not assigned a point. A raw domain score was obtained by adding together points within each domain. The total score within each domain was weighted as previously described15 and then added together to give a total score ranging from 0 to 100. The maximum weighted scores for each subdomain are as follows: 40 for orthostatic intolerance, 5 for vasomotor dysfunction, 15 for secretomotor dysfunction, 25 for GI dysfunction, 10 for urinary dysfunction, and 5 for pupillomotor dysfunction.
CONCLUSIONS: "Our study finds that 67% of individuals with Long COVID are developing dysautonomia. That’s an estimated 38 million Americans with Long COVID dysautonomia, and millions more around the world,” says Lauren Stiles, President of Dysautonomia International and Research Assistant Professor of Neurology at Stony Brook University. (CREDITS: https://bit.ly/3VzS7BQ & https://bit.ly/3VPnU1u )