PodcastDX
In this week’s episode, “Cancer Care in Transition: Precision Medicine, Immunotherapy, and Patient Choice,” we look at how cancer treatment is changing at the exact moment when patients are trying to move from crisis mode into something like a new normal. Precision medicine now uses a person’s genes, tumor markers, and even lifestyle to match them with targeted drugs or immunotherapies instead of one‑size‑fits‑all chemo, while immuno‑oncology has created a growing group of survivors living with long‑term effects and unique follow‑up needs. At the same time,...
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Various Types of Dementia This week on PodcastDX, we’re stepping into the complex world of dementia—not as a single diagnosis, but as a family of conditions that affect memory, thinking, behavior, and independence in different ways. We’ll introduce the most common types of dementia, including Alzheimer’s disease, vascular dementia, Lewy body dementia, frontotemporal dementia, and mixed dementia, where more than one process—often Alzheimer’s plus vascular changes—are happening in the brain at the same time. We’ll also touch on less common causes, such as dementia related to...
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“Rethinking DX: A Digital DSM” looks at how the Diagnostic and Statistical Manual of Mental Disorders (DSM) quietly shapes almost every part of mental health care—from who gets a diagnosis and insurance coverage to how people understand their own symptoms and identities. In this conversation, Lita and Jean Marie unpack what the DSM actually is, why the current DSM‑5‑TR matters, and how a future, fully digital “DSM‑6” could function as a living document that updates more quickly, links to decision‑support tools, and better integrates real‑world data from electronic health...
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Over the next decade, medicine won’t just add new gadgets—it will change what it feels like to be a patient. In this episode of PodcastDX, we explore how AI as a clinical co‑pilot, stem cells and regenerative medicine, genomics and precision care, wearables, and hospital‑at‑home models could reshape everyday care. We talk about the promise of earlier detection and more personalized treatment, the risks around bias, privacy, and hype, and why equity and shared decision‑making must stay at the center as technology races ahead. Most of all, we ask how patients and caregivers can be...
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This week we are discussing the rise of a new type of health care where the patients play a vital role in their medical care. Patients as partners in care are at the heart of shared decision making (SDM), a model where clinicians and patients deliberately work together to choose tests and treatments that fit both best evidence and the patient’s values and life context. What shared decision making means SDM is a collaborative process in which clinicians contribute clinical expertise while patients contribute their goals, preferences, and lived experience. Core...
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At a time when modern medicine is allowing people to enjoy longer, fuller lives, mortality is not always a chief concern. But when a serious illness occurs, the topic becomes unavoidable. This became especially clear during the early days of the COVID-19 pandemic when hospitals were overrun with patients, many with grim prognoses. “The pandemic gave all of us a sense that life can be short and there’s the very real possibility of dying,” says , director of the Palliative Care Program at Yale New Haven Hospital. “It opened the door for us to talk more about death and have a...
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This week we discuss the current status of Mental Health Care. Mental health care is changing, but most experts argue it is not changing fast enough relative to the need, especially on access, equity, and workforce. Where change is too slow Unmet need is huge. In the U.S., millions with a diagnosable condition still receive no treatment each year; a recent national report notes that many adults with mental illness remain uninsured or unable to access care. Global workforce shortages. Nearly 50% of the world’s population lives in countries with fewer...
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The integration of Artificial Intelligence (AI) into post-injury rehabilitation is transforming recovery paradigms by enabling personalized, adaptive, and efficient rehabilitation pathways tailored to individual patient needs. This podcast reviews the current advances in AI applications that facilitate assessment, monitoring, and optimization of rehabilitation programs following injuries. Through machine learning algorithms, wearable sensors, and predictive analytics, AI enhances the precision of therapy plans, tracks patient progress in real-time, and predicts recovery trajectories. The...
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The gut–brain revolution is about treating the digestive system and the nervous system as one integrated network instead of two separate organs that happen to share a body. The gut–brain axis is a bidirectional communication system: the brain influences digestion, motility, and gut sensation, while the gut and its microbiota send chemical, neural, and immune signals back to the brain that can shape mood, cognition, and even neurodegeneration. Central to this loop is the vagus nerve, the longest cranial nerve, which carries most of the traffic from gut to brain and...
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Promising new cancer screening methods are pivoting toward (MCED) blood tests (liquid biopsies) and AI-enhanced imaging, which aim to detect multiple cancer types from a single, non-invasive sample, often before symptoms arise. These technologies, including the and , analyze DNA, proteins, or methylation patterns to identify cancer signals. Multi-Cancer Early Detection (MCED) Blood Tests: These tests, often called liquid biopsies, detect DNA or proteins shed by cancer cells into the bloodstream, identifying early-stage cancers (e.g., ovarian, pancreatic)...
info_outlineOur guest for this week is Sara Olson. Sara (her TikTok name is SKEEETAH) is from the Wolf River area of Wisconsin which just happens to hold the highest concentration of the fungus that causes Blastomycosis. When Sara got Blastomycosis in January 2024, she thought it was 'just the flu'. With a chest xray, she was diagnosed with pneumonia. Several rounds of antibiotics didn't help so she did a CT scan where they found an embolism. Still not knowing anything else, they continued treating her for bacterial pneumonia. They did a swab of her sputum in which her health providers found no bacterial growth, but there was fungal growth. "For some reason they didn't do fungal testing" she was admitted, released and readmitted all the while she was being treated for bacterial pneumonia. The final hospitalization had her O2 levels drop to 30 and she was intubated, her family was called to come and say their goodbyes... You'll have to listen to the interview to learn more. She is lucky to be alive!

- Cause: The outbreak was attributed to the fungus Blastomyces, which is commonly found in soil and decaying matter.
- Exposure: People who participated in river tubing on the Little Wolf River were exposed to the fungus.
- Symptoms: Blastomycosis can cause flu-like symptoms, such as fever, cough, muscle aches, and fatigue, but it can also lead to serious health problems if not treated.
- Transmission: The infection is not spread from person to person.
- Treatment: Blastomycosis can be treated with antifungal medications.
- Outbreak Scale: This outbreak was one of the largest in recent Wisconsin history, with 59 confirmed and 39 probable cases.
- Prevention: Awareness of the potential for infection is key, especially in areas where the fungus is known to be present.
- Endemic Area:Blastomycosis is endemic in the Ohio and Mississippi River valleys, the Great Lakes region, and the southeastern United States according to the CDC.
- Symptoms:Common symptoms include cough, fever, chest pain, fatigue, and skin sores.
- Risk Factors:Individuals with weakened immune systems or chronic illnesses may be more susceptible to severe illness.
- Not Limited to the Wolf River:While the Little Wolf River outbreak was significant, blastomycosis can occur in other areas with suitable environmental conditions.
Blastomyces lives in moist soil in parts of North America. It’s too small to see, so you can breathe it into your lungs without knowing it. There, it can grow and make you sick. It sometimes spreads to your skin or other parts of your body.
It’s hard to avoid breathing in Blastomyces fungus if you live in an area where it’s common. While not entirely preventable, there are some steps you can take to reduce your risk of blastomycosis:
- Avoid disturbing large areas of dirt and dust, especially in areas near water.
- If your job or hobbies expose you to soil that’s likely to contain Blastomyces, wear an N95 (or KN95) respirator mask to help filter the air you breathe.