From Survival to Quality of Life:
PodcastDX
FROM SURVIVAL TO QUALITY OF LIFE: WHY OUTCOMES ARE BEING REDEFINED THE FUNDAMENTAL SHIFT IN MEDICINE For decades, medicine measured success through a singular lens: survival. Did the patient live? Did the procedure work? While these metrics remain important, healthcare is undergoing a profound transformation that redefines what "winning" actually means[1]. The new standard is no longer just extending life—it's enabling patients to live purposefully, functionally, and with dignity[2]. This shift reflects a critical insight: surviving is not the same as living well. WHY OUTCOMES ARE BEING...
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Ai in Medicine Tool Partner or Problem
PodcastDX
AI in medicine is best understood as a powerful tool and a conditional partner that can enhance care when tightly supervised by clinicians, but it becomes a problem when used as a replacement, deployed without oversight, or embedded in biased and opaque systems. Whether it functions more as a partner or a problem depends on how health systems design, regulate, and integrate it into real clinical workflows. Where AI Works Well Decision support and diagnosis: AI can read imaging, ECGs, and lab patterns with very high accuracy, helping detect cancers, heart...
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Medicine in Transition:
PodcastDX
Medicine has transitioned due to massive tech adoption (Electronic Health Records EHRs, Artificial Intelligence AI, Telehealth), shifting patient expectations (consumerism, convenience), the rise of value-based care, new treatments (precision medicine), and increased focus on population health and prevention, all while grappling with rising costs, data security, and persistent access/equity gaps, making healthcare more data-driven, personalized, and digitally integrated but also more complex and fragmented. We try to break it down to try and understand the changes and how they might...
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A Primer on Stem Cells
PodcastDX
This week we discuss stem cells. Having great therapeutic and biotechnological potential, stem cells are extending the frontier in medicine. Not only replace dysfunctional or damaged cells, the so-called regenerative medicine, stem cells may also offer us new perspectives regarding the nature of aging and cancer. This review will cover some basics of stem cells, their current development, and possible applications in medicine. Meanwhile, important remaining challenges of stem cell research are discussed as well. Stem cells are unique, unspecialized cells that can divide to create...
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Functional Fitness
PodcastDX
This week we will discuss the topic of "functional fitness" With the new year upon us many people want to add fitness or getting healthy as goals and we are here to help! Functional fitness is a simple, effective way to keep your body moving and reduce restlessness. It focuses on exercises that help you perform everyday activities more easily and safely—like getting up off the floor, carrying groceries, or reaching for items on a shelf. By training your muscles to work the way you actually use them in daily life, functional fitness reduces injury risk and improves overall quality of...
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Why New Year Resolutions Often Fail
PodcastDX
By the end of the first week of the new year, nearly 77% of New Year’s resolutions have already failed (Norcross, 1988). That’s discouraging—but it doesn’t mean you should stop trying. It means most of us are setting resolutions in ways that don’t work. You aren’t weak or lazy. More often, the problem is a misaligned system—one that relies too heavily on willpower and short-lived motivation. Motivation naturally fades over time, even when our intentions are good. Think about how often you enthusiastically agree to plans weeks in advance, only to feel tired or unmotivated when...
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The Lymphatic System
PodcastDX
The lymphatic system, or lymphoid system, is one of the components of the circulatory system, and it serves a critical role in both immune function and surplus extracellular fluid drainage. Components of the lymphatic system include lymph, lymphatic vessels and plexuses, lymph nodes, lymphatic cells, and a variety of lymphoid organs. The pattern and form of lymphatic channels are more variable and complex but generally parallel those of the peripheral vascular system. The lymphatic system partly functions to convey lymphatic fluid, or lymph, through a network of lymphatic channels,...
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Pancreatic Cancer
PodcastDX
This week we are talking about Pancreatic cancer. This is a type of cancer that begins as a growth of cells in the pancreas. The pancreas lies behind the lower part of the stomach. It makes enzymes that help digest food and hormones that help manage blood sugar. The most common type of pancreatic cancer is pancreatic ductal adenocarcinoma. This type begins in the cells that line the ducts that carry digestive enzymes out of the pancreas. Pancreatic cancer rarely is found at its early stages when the chance of curing it is greatest. This is because it often doesn't cause symptoms until...
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Diabetes Type 1 & 2
PodcastDX
This week we discuss diabetes mellitus, a group of diseases that affect how the body uses blood sugar (glucose). Glucose is an important source of energy for the cells that make up the muscles and tissues. It's also the brain's main source of fuel. The main cause of diabetes varies by type. But no matter what type of diabetes you have, it can lead to excess sugar in the blood. Too much sugar in the blood can lead to serious health problems. Chronic diabetes conditions include type 1 diabetes and type 2 diabetes. Potentially reversible diabetes conditions include prediabetes and gestational...
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Mast Cell Activation Syndrome MCAS
PodcastDX
Mast cell activation syndrome (MCAS) is when you have unexplained episodes of severe symptoms like swelling, diarrhea, vomiting, flushing and itching. Unlike that happen with a specific exposure, MCAS episodes happen without a clear trigger. In some cases, mast cell activation can cause , a severe allergic condition that can be life-threatening. It can cause you to have trouble breathing and drop your to dangerously low levels. Call 911 (or your local emergency service number) or go to the nearest emergency room if you’re experiencing severe anaphylaxis. are a type of immune cell...
info_outlineThis Week on PodcastDX: Understanding POTS with Dr. Diana Driscoll
This week we are honored to welcome none other than Dr. Diana Driscoll, a world-renowned authority on the autonomic nervous system. An optometrist and Fellow of the American Academy of Optometry (FAAO), Dr. Driscoll is internationally recognized for her groundbreaking research on Postural Orthostatic Tachycardia Syndrome (POTS) and other conditions once thought to be “invisible.”
Dr. Driscoll has dedicated her career to improving the lives of those affected by autonomic disorders. Her journey began as a patient herself, battling POTS. Frustrated by the lack of answers, she self-funded much of her research to accelerate progress for patients today. That personal fight has fueled over a decade of innovation in diagnosis and treatment strategies that are transforming patient care.
In this episode, we explore her unique perspective as both a former patient and a leading researcher. Dr. Driscoll shares her story, her research, and her vision for the future of POTS treatment.
What is Postural Orthostatic Tachycardia Syndrome (POTS)?
POTS is a form of orthostatic intolerance that causes the heart to beat abnormally fast when moving from sitting or lying down to standing up. Breaking down the name helps explain the condition:
• Postural: Related to body position
• Orthostatic: Related to standing upright
• Tachycardia: A heart rate above 100 beats per minute
• Syndrome: A collection of symptoms occurring together
Normally, the autonomic nervous system keeps heart rate and blood pressure stable regardless of position. In POTS, that balance is disrupted. The body struggles to constrict blood vessels and regulate heart rate properly, leading to dizziness, lightheadedness, fainting, fatigue, and more.
Who Does POTS Affect?
POTS affects an estimated 1 to 3 million Americans, most often women between the ages of 15 and 50. However, men can develop the condition as well.
Risk factors include:
• Viral or serious infections (such as mononucleosis)
• Pregnancy
• Physical trauma or surgery
• Certain autoimmune conditions (e.g., Sjögren’s syndrome, lupus, celiac disease)
How Does POTS Affect the Body?
When standing, gravity naturally pulls 10–15% of blood into the lower body. Normally, leg muscles and hormonal responses (like the release of epinephrine and norepinephrine) help keep blood circulating back to the brain and heart.
For people with POTS, too much blood pools below the heart. Their blood vessels don’t constrict properly, forcing the heart to compensate by racing. This imbalance causes hallmark symptoms such as dizziness, exhaustion, brain fog, and even fainting.
While POTS is not life-threatening, it can be life-altering. Daily tasks may become difficult, and symptoms often fluctuate over time. The good news: with the right combination of dietary adjustments, medications, and physical activity, many people experience meaningful improvements in their quality of life.
Learn More
Join us as Dr. Diana Driscoll shares her remarkable journey, her patient-centered research, and her continuing mission to bring visibility and solutions to the millions living with POTS.