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Jeff Krasno - Good Stress: The Power of Purposeful Discomfort

The Psychedelic Podcast

Release Date: 02/17/2025

Sam Mandel - 30,000 Infusions Later: Clinical Insights from a Ketamine Pioneer show art Sam Mandel - 30,000 Infusions Later: Clinical Insights from a Ketamine Pioneer

The Psychedelic Podcast

In this episode of The Psychedelic Podcast, Paul F. Austin welcomes Sam Mandel, co-founder and CEO of Ketamine Clinics Los Angeles (KCLA). Find full show notes and links here:  Sam shares his journey co-founding KCLA with his father in 2014, pioneering ketamine infusion therapy when few were exploring its potential for mental health. From humble beginnings in a storage closet to becoming a leading mental health center with over 30,000 infusions administered, Sam discusses the challenges and triumphs of building a patient-centric practice. He explains the science behind ketamine's...

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Simon Ruffell, M.D., Ph.D. - From Skeptic to Student: A Psychiatrist's Path to Becoming a Curandero show art Simon Ruffell, M.D., Ph.D. - From Skeptic to Student: A Psychiatrist's Path to Becoming a Curandero

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In this episode of The Psychedelic Podcast, Paul F. Austin welcomes Dr. Simon Ruffell, a psychiatrist, ayahuasca researcher, and student of curanderismo. Find full show notes and links here: Simon shares his transformative journey from being a skeptical Western psychiatrist to embracing the spiritual dimensions of plant medicine after experiencing what he describes as an "ontological shock" during an ayahuasca ceremony. He discusses his ongoing apprenticeship with Shipibo curanderos in the Amazon, his research into ayahuasca's effects on mental health and epigenetics, and his work bridging...

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In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Dr. Raymond Turpin, a psychologist and psychedelic researcher who has been studying these medicines since 1984. Find full show notes and links here: Dr. Turpin shares his journey from discovering Timothy Leary's writings as a college student to founding the Pearl Psychedelic Institute in North Carolina. He discusses his experience as one of only two sites nationwide to provide MDMA-assisted therapy through the FDA's expanded access program, the profound healing he witnessed in patients with treatment-resistant PTSD, and...

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In this episode of The Psychedelic Podcast, Paul F. Austin welcomes Dr. Katelyn Kalstein, a licensed naturopathic doctor, acupuncturist, and psychotherapist specializing in integrative mental health and psychedelic medicine. Find full show notes and links here:  Dr. Kalstein shares her journey from growing up with natural remedies to her transformative experiences in India and Brazil, where she first encountered ayahuasca and joined the Santo Daime church. She discusses her unconventional career path through naturopathic medicine, neurofeedback at 40 Years of Zen, and as Clinical...

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Norman Ohler - LSD's Secret History: From Swiss Labs to Government Control show art Norman Ohler - LSD's Secret History: From Swiss Labs to Government Control

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In this episode of The Psychedelic Podcast, Paul F. Austin welcomes New York Times bestselling author Norman Ohler. Find full show notes and links here: Norman shares his deep research into the hidden history of LSD, revealing the untold connections between Arthur Stoll (CEO of Sandoz), Nazi Germany, and the CIA's MKUltra program. He explains how LSD's development as a mental health medicine was derailed by intelligence agencies seeking a "truth drug" for interrogations, and how the substance traveled from Swiss laboratories to Nazi concentration camps and eventually to American universities....

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In this episode of The Psychedelic Podcast, Paul F. Austin welcomes Dr. Tracy Townsend, a Harvard-trained physician who left orthopedic surgery to become a licensed psilocybin facilitator in Oregon. Find full show notes and links here: Dr. Townsend shares her journey from conventional medicine to psychedelic facilitation, describing how her own transformative experiences with plant medicines led her to question the limitations of Western healthcare. She discusses the Oregon psilocybin model, challenges within the current regulatory framework, and draws fascinating parallels between physical...

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In this episode of The Psychedelic Podcast, Paul F. Austin welcomes Ava Johanna, founder and CEO of The Academy of Breath. Find full show notes and links here:  Ava shares her journey from corporate burnout and weekend escapism to discovering breathwork as a powerful, accessible tool for transformation. She discusses how breathwork provided the same ecstatic states she once sought through substances, but in a healing, sustainable way. Beyond the practice itself, Ava offers valuable insights for coaches and practitioners looking to build successful businesses in the wellness space,...

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Austin Perlmutter, M.D. - Unsticking the Brain: Psychedelics, Inflammation, and Mental Health show art Austin Perlmutter, M.D. - Unsticking the Brain: Psychedelics, Inflammation, and Mental Health

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In this episode of The Psychedelic Podcast, Paul welcomes Dr. Austin Perlmutter, a board-certified internal medicine physician, New York Times bestselling author, and researcher. Find full show notes and links here: Dr. Perlmutter shares his perspective on how psychedelics can help "unstick" the brain from harmful patterns, explores the relationship between inflammation and mental health, and discusses his current research on ayahuasca's effects on epigenetics and the microbiome. From understanding the biological basis of our mental states to finding balance in a modern world that often works...

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Nick Musica - SEO to ESP: Psychedelics, Pattern Recognition & Animal Telepathy show art Nick Musica - SEO to ESP: Psychedelics, Pattern Recognition & Animal Telepathy

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In this episode of The Psychedelic Podcast, Paul F. Austin welcomes Nick Musica, founder and CEO of Optics In and psychic animal communicator. Find full show notes and links here: Nick shares his fascinating journey from SEO expert to animal communicator, bridging the worlds of technical analysis and spiritual connection. He discusses how plant medicine experiences and meditation opened channels of communication with animals, particularly through his relationship with his cat Chucky. The conversation explores the intersection of consciousness, communication, and how animals can serve as...

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In this episode of The Psychedelic Podcast, Paul F. Austin welcomes Robert Edward Grant, a polymath inventor, entrepreneur, mathematician, and philosopher. Grant shares his transformative journey from successful businessman to consciousness explorer, discussing how psychedelics enhanced his understanding of mathematics, sacred geometry, and universal truth. He explores the relationship between science and spirituality, the nature of reality, and his groundbreaking discoveries in ancient Egyptian archaeology. Grant offers profound insights into the role of unconditional love in personal...

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More Episodes

In this episode of The Psychedelic Podcast, Paul F. Austin welcomes Jeff Krasno, entrepreneur, author, and wellness pioneer. 

Find full show notes and links here: https://thethirdwave.co/podcast/episode-291/?ref=278

Jeff shares his transformative journey from leading Wanderlust to confronting his own health crisis, which led to profound insights about stress, healing, and human potential. He discusses his new book "Good Stress," exploring how embracing evolutionary-aligned challenges can enhance our wellbeing. Jeff offers a unique perspective on rewilding our lives, the intersection of physical and spiritual health, and finding freedom from the fear of death through understanding our deep connection to nature and the cosmos.

Jeff Krasno is the co-founder and CEO of Commune, a masterclass platform for personal and societal well-being and co-creator of Wanderlust, a global series of wellness events. He hosts the Commune podcast, interviewing a wide variety of luminaries from Deepak Chopra and Marianne Williamson to Matthew McConaughey and Gabor Maté.

His latest venture expands Jeff’s personal story and protocols into a book, "Good Stress: The Benefits of Doing Hard Things" (Hay House, March 2025). The book dives deeper into the concepts from the course, distilling insights from over 400 podcast conversations Jeff has conducted, along with his personal experiences applying these ideas to transform his own health. It explores deliberate, self-imposed behaviors that promote social, psychological, and physical well-being, offering both a philosophical exploration of true wellness and practical steps to achieve it.

Highlights:

  • Jeff's personal health crisis and transformation from Wanderlust CEO to wellness advocate
  • The concept of "good stress" and its role in human evolution and adaptation
  • Understanding rewilding as a path to physical and psychological health
  • The intersection of physical practices and spiritual development
  • How modern comfort may be undermining our natural resilience
  • The importance of reconnecting with ancestral movement patterns
  • Reframing our relationship with death and mortality
  • The unity of physical and metaphysical in human experience

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