Copper, Mitochondria Grey Hair & Autism: The Missing Link No One Is Talking About
Pushing The Limits
Could a simple mineral deficiency be driving mitochondrial dysfunction in autism? In this episode I sit down with Melissa Atchley from MitoSynergy to hear her personal story of using BioCopper1 with her son on the autism spectrum — and the changes she saw that no one expected. I break down the science behind it: Dr Richard Frye's research showing Complex IV dysfunction in children with ASD, the brand new April 2026 Science Advances paper linking copper deficiency directly to ASD-like behaviours through mitochondrial damage and impaired myelination, and why the type of copper matters — Cu1+...
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Klotho, Peptides & Limitless Longevity — Dr. Alex Grinberg & Dr. Dave Jenkins
Pushing The Limits
These two doctors are building a clinic where the most advanced longevity therapies have no limits. Dr. Alexander Grinberg (Infinity Epigenetics, San Francisco) and Dr. Dave Jenkins (Bredesen-trained, 40+ years clinical experience) are combining peptide therapy, regenerative medicine, and personalised protocols at a level most people don't know exists. From Klotho protein restoring cognitive function in head injury patients to mitochondrial peptides that can rescue dying cells — this conversation covers the cutting edge of what's actually possible right now. About the Guests Dr. Alexander...
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The 7 Reasons Your Cells Age (And How to Stop It) Dr Sandra Kaufmann
Pushing The Limits
Your cells start failing at 35. Dr Sandra Kaufmann reveals the 7 systems breaking down — and how to stop it. Your cells start failing at 35. Dr Sandra Kaufmann reveals the 7 systems breaking down — and how to stop it. 👉 FREE Longevity Cheat Sheet — subscribe to my weekly newsletter: Description: Your cells start failing at 35. Dr Sandra Kaufmann reveals the 7 systems breaking down — and how to stop it. Dr Sandra Kaufmann is a cell biologist, physician, and creator of the Kaufmann Protocol — the first comprehensive rating system for anti-aging supplements. In this episode...
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The One System Behind ALL 14 Hallmarks of Aging — And How to Target It | Courtney Van Bussum
Pushing The Limits
Your immune system isn't just fighting off colds. It's the foundational system that influences all 14 hallmarks of aging — and when it declines, everything downstream accelerates. In this episode, I sit down with Courtney Van Bussum, COO of Longevity Launch Labs, to dive deep into immunosenescence — the aging of the immune system — and why it starts far earlier than most people realise. We unpack what Stanford's landmark 1000 Immunomes Project revealed about the real driver of biological aging, why your supplement stack might be missing the most important piece, and how we built...
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Reverse Alzheimers with Dr Dave Jenkins
Pushing The Limits
What if you could know 20 YEARS before symptoms appear whether you're heading for Alzheimer's? And what if there was a proven way to reverse early cognitive decline? In this episode, I sit down with my dear friend Dr. Dave Jenkins — the leading Dr. Dale Bredesen Protocol practitioner in the Southern Hemisphere — to unpack the p-Tau 217 blood test revolution and the stunning results from Bredesen's latest randomised controlled trial. Dr. Dave breaks down how a simple finger-prick blood test can now detect the Alzheimer's process with 95% certainty up to TWO DECADES before memory symptoms...
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Robots in Healthcare: Tesla Optimus, Terafab - Cern Basher
Pushing The Limits
The global healthcare system is heading for a catastrophic workforce shortage — 10 to 15 million workers short by 2030. In this episode, financial analyst and Tesla expert Cern Basher (@cernbasher) returns to break down how humanoid robots like Tesla's Optimus could be the only scalable solution, why New Zealand is uniquely positioned to lead a healthcare robotics pilot, and what the Terafab chip factory and Digital Optimus mean for the timeline. From fleet learning to the privacy concerns, from Moxy robots already in 25+ US hospitals to Elon Musk's vision of billions of robots powered by...
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Robots In Healthcare: Why This Changes Everything For The Future Of Medicine
Pushing The Limits
🔬 This episode is sponsored by MitoSynergy Copper 1+ Most copper supplements use poorly absorbed oxidised forms that can actually increase free radical damage. MitoSynergy's patented BioCopper1 (Cunermuspir) is a copper-niacin chelate that delivers reduced copper (Cu1+) directly to your mitochondria, supporting ATP production at cytochrome c oxidase. I've been personally testing MitoActivator EX and have noticed a real difference in training power and energy output. 👉 Try it: https://mitosynergy.com/lisaTamati (10% off with this link) -------------------------------------------- New...
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Wall Street Macro Investor Reveals: HRV, Longevity, Bitcoin & The AI Revolution | Jordi Visser
Pushing The Limits
Wall Street veteran and macro investor Jordi Visser spent 30 years managing billions in risk — building turbulence models to predict market crashes before they happened. Then he turned that exact same framework on his own biology. The result? He raised his HRV from the high 20s to the 60s over six years. Not with a protocol. With a system. Jordi is back on Pushing The Limits for round two and this episode covers everything. We go deep on HRV and longevity — what your wearable is actually telling you, why your gut health is the foundation of your HRV, why breathwork beats meditation, why...
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The Dark Side of NMN Nobody Tells You About
Pushing The Limits
Is your NAD+ supplement actually working against you? Millions of people are taking NMN or NR thinking they're doing something smart for their longevity. And the science behind NAD+ is genuinely extraordinary. But the way most people are supplementing it is incomplete — and there's growing evidence it could be creating downstream harm most people never connect back to their supplement. In this episode I break down the full NAD+ story — the methylation trap, the CD38 drain, why high-dose NMN may be elevating your cardiovascular risk markers, and...
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Trillions of AI Agents Are Coming — Cern Basher on Why Bitcoin Is the Solution
Pushing The Limits
Episode Title: Tesla's Building A Robot Army — And A $1.5 Trillion Merger | Cern Basher Short Description: Bitcoin isn't money — it's a cyber security technology. And we're going to need it desperately. Cern Basher, CFA, breaks down why AI agents will choose Bitcoin, the Tesla robotaxi economics, the SpaceX–xAI mega-merger, and why Strategy might be the world's largest digital security company. Full Description: How do you constrain trillions of AI agents roaming the internet? Not with passwords and code — AI will hack all of that. You do it with physics. You do it with...
info_outlineIs your NAD+ supplement actually working against you?
Millions of people are taking NMN or NR thinking they're
doing something smart for their longevity. And the science
behind NAD+ is genuinely extraordinary. But the way most
people are supplementing it is incomplete — and there's
growing evidence it could be creating downstream harm most
people never connect back to their supplement.
In this episode I break down the full NAD+ story — the
methylation trap, the CD38 drain, why high-dose NMN may be
elevating your cardiovascular risk markers, and what an
intelligent systems-level approach actually looks like.
I co-developed NAD+ Next Gen with Peter Lehrke— and in this episode I walk
you through exactly why every ingredient is in the formula.
WHAT WE COVER:
- The 2023 Nature Cardiovascular Research findings on NMN & ADMA
- How high-dose NMN drains your SAM pool and disrupts dopamine,
DNA methylation and homocysteine
- CD38 — the biggest NAD+ drain in ageing nobody talks about
- The bathtub model: precursors, drains, sirtuin efficiency
- Why niacinamide may be smarter than high-dose NMN
- EGCG, resveratrol, apigenin, quercetin, rutin — the why
behind each ingredient
- 6 practical takeaways including which blood test to get now
KEY LINKS:
NAD+ Next Gen → https://aevumlabs.co.nz
Rejuvenate Pro → https://shop.lisatamati.com
Pushing The Limits community → https://www.lisatamati.com
GET YOUR HOMOCYSTEINE TESTED:
Optimal: below 7–8 µmol/L
Above 10 µmol/L: address your methylation cycle urgently
Lisa Tamati is a functional health practitioner, longevity
specialist, co-founder of Aevum Labs, host of Pushing The
Limits, and former elite ultra-endurance athlete with 25
years and 140+ ultramarathons across the world's most
extreme environments.
Visit Lisa's website
shop.lisatamati.com
www.Yourhealthcompass.org
www.Myimmuneage.life