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The One Test That Never Expires: Why Your DNA Is the Most Important Thing You'll Ever Test

Pushing The Limits

Release Date: 09/18/2026

The One Test That Never Expires: Why Your DNA Is the Most Important Thing You'll Ever Test show art The One Test That Never Expires: Why Your DNA Is the Most Important Thing You'll Ever Test

Pushing The Limits

I ran 70,000km across the world's toughest deserts to lose weight, and I got heavier, more inflamed and sicker every year. I assumed the problem was discipline. It took one genetic test to show me it never was. In this solo episode I make the case that your DNA is the single most valuable test you will ever do. Not because it tells you the most, but because it is the only test whose result is still true in fifty years. Your bloods reflect the last few weeks. Your microbiome shifts with every trip and every course of antibiotics. Your hormones move across the month and the decade. Your DNA does...

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More Episodes

I ran 70,000km across the world's toughest deserts to lose weight, and I got heavier, more inflamed and sicker every year. I assumed the problem was discipline. It took one genetic test to show me it never was.

In this solo episode I make the case that your DNA is the single most valuable test you will ever do. Not because it tells you the most, but because it is the only test whose result is still true in fifty years. Your bloods reflect the last few weeks. Your microbiome shifts with every trip and every course of antibiotics. Your hormones move across the month and the decade. Your DNA does not move at all.

I go through all eight areas a comprehensive genetic panel covers, what you actually learn from each one, and why a variant is a tendency rather than a verdict.

IN THIS EPISODE

My own results, and the cascade that explains twenty-five years of getting it wrong
Why genetics is different from every other test you will ever do
Genetics loads the gun, environment pulls the trigger: what that actually means in practice
The single-gene trap, and why the MTHFR obsession has it upside down
Digestion, energy, hormones, stress and cognition, inflammation, athletic performance, DNA repair and detoxification, one at a time
The difference between nutritional dosing and nutrigenomic dosing, and why more vitamin D was not working for me
Why genetics alone is not enough, and what has to sit alongside it
Why it is almost never discipline

THE DNA BLUEPRINT PACKAGE

Practitioner-only genetic testing, ninety-two genes and a hundred and thirteen variants across a report of roughly a hundred and twenty-one pages, read by me alongside a full Cell Blueprint assessment and turned into a complete personal health programme in a ninety-minute one-on-one.

Available throughout New Zealand. Australia coming soon.
https://www.lisatamati.com/dna/

GO DEEPER

Dr Sam Shay on methylation, inflammation and exercise-induced obesity:
https://www.lisatamati.com/podcast--dr-sam-shay_1/

Dr Mansoor Mohammed on how your variants change what you eat and how you train:
https://www.lisatamati.com/podcast-mansoor-mohammed/

Read the long-form article:
https://www.lisatamati.com/blog/

ALSO FROM LISA

Re:juvenate Pro, the foundational immune ageing formula from Aevum Labs:
https://shop.lisatamati.com/pages/rejuvenate

Re:NRG, our next-generation NAD support, is coming. Join the waitlist for first access:
https://shop.lisatamati.com/pages/nad-next-gen-waitlist

Weekly longevity insights, free:
https://www.lisatamati.com/lisa

Questions or feedback: [email protected]

Pushing the Limits is hosted by Lisa Tamati, genetics practitioner, co-founder and Chief Science Officer of Aevum Labs, and former professional ultra-endurance athlete. Author of three books and one audiobook.