Gene Therapy & Rare Diseases with Assoc. Prof Leszek Lisowski (449)
Release Date: 10/25/2025
Science in Oz: The Good, The Bad and The Ugly with Dr. Catherine Ball (452)
Shirtloads of Science
In this episode, futurist and award-winning scientist Dr Catherine Ball dives into the state of science in Australia, uncovering the good, the bad, and the overlooked. From humanoid robotics and wearable exoskeletons transforming healthcare, to Australia’s lagging space economy, Ball offers an unflinching look at where we stand. She also highlights world-class cancer detection research happening in Australia, like PROCAN and early ovarian cancer screening innovations that deserve far more recognition. Passionate about inspiring the next generation, Ball shares her advice for young...
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Food Additives: What’s Safe, What’s Not? with Prof. Clare Collins (451)
Shirtloads of Science
In this episode, I’m joined by Professor Clare Collins, Australian dietitian and Professor of Nutrition and Dietetics at the University of Newcastle. Clare is my go-to expert when it comes to all things nutrition, and today she’s here to unpack the often confusing world of processed and ultra-processed foods. We dive into what really separates the two, explore the role of additives, emulsifiers, and flavour enhancers, and discuss how some of these ingredients, designed to make foods more appealing, may be doing our health more harm than good. Plus, she shares practical,...
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Innovative Nanotechnology for Cancer Detection with Dr. Renee Goreham (450)
Shirtloads of Science
In this episode, we chat with Dr. Renee Goreham, a physicist and nanotechnologist at the University of Newcastle, and passionate science communicator. Renee is an experimental physicist exploring how our breath could hold the key to detecting lung cancer early—by identifying specific proteins as biomarkers. We also delve into her PhD student’s exciting research into a new red-light laser diagnostic tool for breast cancer. Along the way, Renee breaks down the basics of cell biology and shares her inspiring, non-linear journey through physics, nanotech, and beyond. A brilliant example...
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Gene Therapy & Rare Diseases with Assoc. Prof Leszek Lisowski (449)
Shirtloads of Science
In this episode, we speak with Associate Professor Leszek Lisowski, Head of the Translational Vectorology Unit at the Children’s Medical Research Institute (CMRI), about the cutting-edge world of gene therapy. He explains how viral vectors are engineered to deliver life-saving treatments for rare genetic diseases - many of which are so uncommon, they’re only known by the name of the affected gene. Despite being often overlooked, genetic diseases impact 10% of adults and 30% of children in hospitals. Leszek sheds light on the challenges of diagnosis, the promise of emerging genetic testing,...
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The Brain’s Energy Bill: From Childhood to Old Age with Assoc. Prof Sharna Jamadar (448)
Shirtloads of Science
In this episode, we’re joined by Associate Professor Sharna Jamadar, a cognitive neuroscientist at Monash University, to explore how the brain uses energy, and how that changes across the lifespan. Did you know that a 10-year-old’s brain uses over 50% of the body’s total energy, compared to just 20% in adults? We dive into why younger brains work harder, the role of synaptic pruning and proliferation, and how the brain’s organisation impacts cognitive efficiency. We also touch on the importance of glucose metabolism and its connection to age-related disorders like Alzheimer’s. A...
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Onionlike Layers of Exploding Stars with Prof. Geraint Lewis (447)
Shirtloads of Science
My go-to guy for all cosmic things Prof. Geraint Lewis, astrophysicist at the University of Sydney, returns to unpack a fascinating New York Times article on a newly observed “onionlike” space explosion that may reveal a new type of supernova. We dive into what actually happens when a star dies, the onion-layer buildup of elements through nuclear fusion, and how these cataclysmic blasts forge the building blocks of life on Earth. Plus, we explore what this might mean for the ultimate fate of our own Sun. Linkedin: Geriant Lewis
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The Aftermath of Cosmic Collisions with Prof. Geraint Lewis (446)
Shirtloads of Science
In this episode, friend of the show Geriant Lewis, Professor of Astrophysics at the Sydney Institute for Astronomy within the University of Sydney, joins us to unpack a fascinating New Scientist article theorising on how a strange line of dwarf galaxies may have formed. We explore how high-speed collisions between dwarf galaxies can scatter gas and stars across space, sometimes giving rise to entirely new tidal galaxies. Geraint explains the latest thinking on where these dwarf galaxies come from and how these cosmic smash-ups might even shed light on one of the biggest mysteries...
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The Human Side of Misinformation Part 2 with Assoc. Prof. Marian-Andrei Rizoiu (445)
Shirtloads of Science
In part two, Associate Professor Marian-Andrei Rizoiu from the University of Technology Sydney explains how misinformation and toxic online cultures spread. We dive into the “manosphere pipeline” targeting boys as young as 10, its real-world impacts on schools and families, and how it can escalate into radicalisation. Rizoiu outlines his team’s six-stage pipeline - from passive curiosity to active involvement - and why simply giving people facts doesn’t solve the problem. Instead, this is a human challenge, and his lab is exploring new ways to diffuse and counter online misinformation...
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The Human Side of Misinformation Part 1 with Assoc. Prof. Marian-Andrei Rizoiu (444)
Shirtloads of Science
In this episode, I sit down with Marian-Andrei Rizoiu, Associate Professor and head of the Behavioral Data Science Lab at the University of Technology Sydney. Drawing on a three-year research project into the misinformation ecosystem, he reveals that online conspiracies aren’t just about false facts. Instead, they meet deep human needs for belonging and identity. We explore the idea that misinformation is less a content problem and more a human problem, fueled by the attention economy. Rizoiu also weighs in on the growing debate around restricting social media use, such as...
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Science Under Siege with Prof. Michael Mann & Prof. Peter Hotez (443)
Shirtloads of Science
In this episode, we sit down with two of today’s most prominent defenders of science: Professor Michael Mann, world-renowned climate scientist, and Professor Peter Hotez, vaccine researcher and advocate for global health equity. Together, they’ve co-authored Science Under Siege, a powerful new book exposing the forces behind the global anti-science movement. We explore the surprising parallels between climate denial and vaccine misinformation, and how both Mann and Hotez have faced personal attacks simply for standing by the evidence. They break down the five key drivers of anti-science -...
info_outlineIn this episode, we speak with Associate Professor Leszek Lisowski, Head of the Translational Vectorology Unit at the Children’s Medical Research Institute (CMRI), about the cutting-edge world of gene therapy. He explains how viral vectors are engineered to deliver life-saving treatments for rare genetic diseases - many of which are so uncommon, they’re only known by the name of the affected gene. Despite being often overlooked, genetic diseases impact 10% of adults and 30% of children in hospitals. Leszek sheds light on the challenges of diagnosis, the promise of emerging genetic testing, and how his work is paving the way for more accurate, effective therapies.
Linkedin: Children's Medical Research Institute, Leszek Lisowski
Facebook: @jeansforgenes
Instagram: @jeansforgenesau