#527: How to Prevent & Treat Hypertension – Dr. Mohammed Alo, DO
Release Date: 06/25/2024
#544: Genetic Variants and Response to Nutrients – Martin Kohlmeier, MD PhD
Sigma Nutrition Radio
In the realm of nutrition science, individual differences are more profound and impactful than many realize. For decades, we’ve developed dietary recommendations with a “one-size-fits-all” approach, assuming that most people respond similarly to specific nutrients. But Dr. Martin Kohlmeier, a pioneer in precision nutrition, challenges this very notion. How might an individual’s genetic makeup alter their need for certain nutrients? With advances in nutrigenetics, we’re beginning to see how personalized nutrition could bridge long-standing gaps in dietary efficacy. Dr. Kohlmeier’s...
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Sigma Nutrition Radio
- Come join us! Get 20% off all subscription options. - The best online database for looking at the evidence of foods, nutrients, supplements and health outcomes just got revamped. - Get 30% off their breakdowns of the latest training and nutrition research for strength trainees. - Get Alan's deepdive analysis of methodology and study interpretation.
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#543: Eye Health & Nutrition – Prof. John Nolan
Sigma Nutrition Radio
In this episode, we dive deep into the world of ocular nutrition with Professor John Nolan, exploring how specific nutrients can play crucial roles in preserving eye health, improving vision and supporting cognitive function. With age-related macular degeneration (AMD) affecting millions globally, Professor Nolan sheds light on groundbreaking research showing how certain carotenoids—natural pigments found in plant foods—could impact eye health and perhaps even neurodegenerative conditions like Alzheimer’s disease. But what are these compounds exactly, and why are they so impactful?...
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#542: Nutrients for Cognitive Performance in Sports – Prof. Shawn Arent, PhD
Sigma Nutrition Radio
In the world of sports nutrition, understanding how different supplements and nutrients impact not just physical performance but also cognitive function is rapidly gaining traction. Athletes are constantly seeking that competitive edge, and while many are familiar with the benefits of carbohydrates and caffeine for energy and focus, there’s much more at play. Emerging research is highlighting the roles of compounds like creatine and omega-3s, not only for muscle recovery but also for brain health, particularly following traumatic brain injuries (TBI). Beyond the usual suspects of performance...
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#541: Lean Mass Hyper Responders & the Lipid Energy Model: Do the Claims Stand Up to Scrutiny?
Sigma Nutrition Radio
When discussing cardiovascular health, few topics stir as much debate as cholesterol, particularly in relation to low-carb and ketogenic diets. Recently, there’s been significant attention given to a proposed model that suggests high LDL cholesterol may not pose the same cardiovascular risk in certain individuals, specifically those labeled as “lean mass hyper-responders.” This raises important questions: Is it possible that high cholesterol might not be dangerous for everyone? Or are we witnessing a dangerous misinterpretation of the science? In this episode, we break down the ideas...
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Fasting for Health: What Do We Know? (SNP34)
Sigma Nutrition Radio
Fasting has gained immense popularity as a dietary approach, but what does the scientific evidence say about its health benefits? Studies have explored how fasting might influence metabolic markers, energy expenditure, and even aging. However, while fasting shows promise in some animal models, translating these effects to humans is less clear. A key part of the debate centers on whether fasting offers unique health advantages or whether its benefits stem primarily from reduced calorie intake. Time-restricted eating and intermittent fasting protocols show promise in regulating appetite and...
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#540: How Can We Improve Body Image and Self-Esteem Without Physique Change? – Gabrielle Fundaro, PhD & Eric Trexler, PhD
Sigma Nutrition Radio
Body image and self-worth are deeply intertwined concepts that influence how we see ourselves and interact with the world. Many people believe that changing their physique is the key to improving their body image, but is it really that simple? This connection between appearance and self-esteem raises important questions about how we define confidence and whether our sense of worth should be tied to how we look. Our relationship with food plays a crucial role in how we view ourselves. While some see food as fuel, others attach much more significance to their eating habits, often linking dietary...
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#539: How Does Carbohydrate Availability Impact Resistance Training? – Cliff Harvey, PhD & Eric Helms, PhD
Sigma Nutrition Radio
Some suggest that, since individual lifts or short-duration efforts don’t rely heavily on glycogen, carb intake might not be critical for strength athletes. If glycogen depletion isn’t a pressing issue, could athletes thrive on lower-carb diets without sacrificing performance? Or could there be overlooked benefits to having greater carbohydrate availablily in those sessions? In strength sports and resistance training, do carbohydrates play an important role or not? Are carbohydrates really necessary for resistance training? How does training volume, intensity and goals impact the...
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#538: Can Fish Oil Supplementation Increase Risk of Irregular Heart Rhythms?
Sigma Nutrition Radio
Omega-3 fatty acids are often viewed as beneficial or, at worst, neutral supplements when it comes to supporting cardiovascular health, lowering triglycerides, and offering anti-inflammatory effects. Much of the focus in recent years has centered on understanding how significant these benefits are, particularly for heart health, with many studies highlighting the potential for omega-3s to play a positive role in reducing cardiovascular risk. However, an emerging concern has complicated the conversation around omega-3 supplementation. Several large trials, including the REDUCE-IT and STRENGTH...
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#537: Appetite Regulation, Metabolic Compensation and More – Stephan Guyenet, PhD
Sigma Nutrition Radio
This is an “ask me anything” (AMA) episode with Dr. Stephan Guyenet, an expert in obesity neuroscience and eating behavior. This episode was originally published on . If you’re interested in subscribing to Sigma Nutrition Premium, then check all the details . Questions Answered: [04.27] If we surgically remove adipose tissue, do leptin levels suddenly drop? How would this impact hunger over time? [06.56] How does chronic energy restriction (or following a crash diet) affect long-term appetite regulation? [13.21] How do anorexia and pronounced obesity...
info_outlineHypertension, commonly known as high blood pressure, is a silent yet prevalent health issue that affects millions of people worldwide. Often going unnoticed until significant damage has been done, hypertension can lead to severe cardiovascular complications if not properly managed.
Mechanistically, the causes of hypertension are complex, involving both genetic and lifestyle factors. The management of hypertension presents multifaceted challenges, encompassing both pharmaceutical treatments and lifestyle modifications.
From a prevention and management standpoint, understanding the interplay between genetics and lifestyle is crucial. This raises several important questions…
- To what extent do genetic factors contribute to hypertension risk compared to lifestyle choices, and how does this interaction influence disease progression?
- What role does lifestyle play in managing hypertension, and is there evidence supporting the influence of specific dietary patterns and nutrients, particularly sodium and potassium, on blood pressure control?
- How do exercise and physical activity impact blood pressure, and what types of exercise are most beneficial for individuals with or at risk of hypertension?
- What are the main categories of antihypertensive medications, and how do these drugs work to lower blood pressure?
- What are the potential side effects, and how should clinicians decide on the best treatment approach for individual patients?
In this episode, we are joined by Dr. Mohammed Alo, a board-certified cardiologist and internal medicine specialist, who will help us understand the intricacies of hypertension and how it can be effectively controlled.
Links:
- Go to episode page
- dralo.net/
- Receive our free weekly email: the Sigma Synopsis
- Subscribe to Sigma Nutrition Premium
Timestamps:
- 03:28 Dr. Alo’s Background and Expertise
- 08:40 Understanding Blood Pressure and Its Implications
- 10:26 Causes and Diagnosis of High Blood Pressure
- 12:42 Lifestyle Modifications and Treatment Options
- 30:26 Medications for Blood Pressure Management
- 38:34 Combination Therapy and Patient Variability
- 43:11 Debunking Myths About Sodium and Blood Pressure
- 57:29 Exercise and Lifestyle Interventions