Revolutionizing Humanity And Tech With Pablos Holman - TWMJ #1033
Release Date: 04/26/2026
High Performing Teams With Ron Friedman - TWMJ #1058
Thinking With Mitch Joel
Welcome to episode #1058 of Thinking With Mitch Joel (formerly Six Pixels of Separation). is an award-winning social psychologist, bestselling author, and expert on the science of high performance (he’s also a personal friend). His previous books, and , explored how organizations can create better workplaces and how individuals can learn from the world's most successful performers. Now, in his new book, , Ron turns his attention to a deceptively simple question: What separates extraordinary teams from everyone else? Drawing on research involving thousands of professionals across...
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How Change Really Works With Julia Dhar - TWMJ #1057
Thinking With Mitch Joel
Welcome to episode #1057 of Thinking With Mitch Joel (formerly Six Pixels of Separation). is a leading voice in behavioral science and organizational transformation, and the founder of the at . A three-time Champion and known for her work on productive disagreement, Julia has spent much of her career exploring a deceptively simple question: Why do organizations invest so much time, money, and human potential in change... only to fail so often? In her new book, , co-authored with and , she challenges the conventional wisdom that people are naturally resistant to change. Instead, she argues...
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The Human Side Of Business With Mike Michalowicz - TWMJ #1056
Thinking With Mitch Joel
Welcome to episode #1056 of Thinking With Mitch Joel (formerly Six Pixels of Separation). has spent much of his career trying to solve a problem he describes simply: eradicating entrepreneurial poverty. As the bestselling author of and numerous other books on entrepreneurship and business, Mike has built a body of work around challenging conventional wisdom and finding practical systems that work with human behavior rather than against it. He's also an old friend, which means our conversations have a tendency to wander into some unexpected places... and this one certainly does. His latest...
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Axios And The Art Of Simplification With Roy Schwartz - TWMJ #1055
Thinking With Mitch Joel
Welcome to episode #1055 of Thinking With Mitch Joel (formerly Six Pixels of Separation). is the co-founder of and CEO of , where he has helped redefine how organizations communicate in an age of information overload. Before launching Axios alongside and , Roy helped build into one of the most influential political news organizations in the world. Today, Axios reaches millions of readers through its distinctive format, while Axios HQ helps some of the world's largest organizations communicate more clearly and effectively. In his new book, , Roy argues that our biggest challenge isn't a...
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Creating The Apple Store And Reinventing Retail With Ron Johnson - TWMJ #1054
Thinking With Mitch Joel
Welcome to episode #1054 of Thinking With Mitch Joel (formerly Six Pixels of Separation). is one of the most influential retail innovators of the modern era. Best known for creating the (alongside ), he helped redefine what a physical store could be, transforming retail from a place that simply sold products into a destination centered on service, learning, and human connection. Before , Ron helped reshape 's merchandising strategy through groundbreaking designer collaborations, and later served as CEO of during one of the industry's most ambitious retail transformations (and it did not go...
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Great Companies With Eric Ries - TWMJ #1053
Thinking With Mitch Joel
Welcome to episode #1053 of Thinking With Mitch Joel (formerly Six Pixels of Separation). is one of the most influential entrepreneurs and management thinkers of the past two decades. Best known as the creator of the movement, his ideas fundamentally changed how founders, innovators, and established organizations build products, test ideas, and bring innovation to market. His work has shaped startups, Fortune 500 companies, governments, and nonprofits around the world, earning him recognition as one of the defining voices on modern entrepreneurship. In his latest book, , Eric turns his...
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The Power Of Brands With Lifang He - TWMJ #1052
Thinking With Mitch Joel
Welcome to episode #1052 of Thinking With Mitch Joel (formerly Six Pixels of Separation). has spent more than two decades helping some of the world's most influential technology companies build products that people don't just use... they love. A global brand strategist and product marketing leader, she has led branding, go-to-market, and growth initiatives for companies including , , and . During her time at Apple's longtime creative agency, , she helped shape global launches, giving her a front-row seat to one of the most successful product introductions in history. Her new book, , argues...
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Data Inspired With Sebastian Wernicke - TWMJ #1051
Thinking With Mitch Joel
Welcome to episode #1051 of Thinking With Mitch Joel (formerly Six Pixels of Separation). has built his career at the intersection of data science, artificial intelligence, economics, and decision-making. He leads the Data Science and AI team at , one of Europe's leading economics consultancies, and has become widely recognized for his ability to make complex ideas about data both accessible and deeply human. Many people first encountered Sebastian through his memorable , which cleverly used data to satirize TED Talks themselves, but his work has always been driven by a much bigger question:...
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Navigating Future Shock With Fredric Marshall - TWMJ #1050
Thinking With Mitch Joel
Welcome to episode #1050 of Thinking With Mitch Joel (formerly Six Pixels of Separation). has spent decades helping people navigate change. An entrepreneur, investor in AI startups, CEO of , and advisor on leadership and transformation, he has watched multiple waves of technological disruption unfold from the inside. His latest book, , revisits 's famous concept of "" and argues that today's anxiety isn't a personal failing... it's the predictable result of living through an era where change, information, and technological progress are arriving faster than most people can absorb. In this...
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AI Mindsets With Farid Mheir - TWMJ #1049
Thinking With Mitch Joel
Welcome to episode #1049 of Thinking With Mitch Joel (formerly Six Pixels of Separation). has spent four decades at the intersection of engineering, business strategy, and digital transformation. Trained as a microelectronics engineer, he helped pioneer online grocery commerce with in the mid-1990s before building e-commerce platforms for major retailers across North America and Europe. Today, through his , and as a faculty member at the , Farid advises executives on AI strategy and organizational transformation. His new book, , distills decades of experience into thirty-one practical...
info_outlineWelcome to episode #1033 of Thinking With Mitch Joel (formerly Six Pixels of Separation).
We spent the last twenty-five years calling software “technology,” which was convenient, profitable and just a little bit delusional. Apps got smarter. Feeds got stickier. Ads got creepier. Dashboards got dashboards. Meanwhile, the real world kept asking harder questions. How do we produce enough clean energy for eight billion people? How do we build things again? How do we manufacture without waste? How do we use AI for science, not just better chatbots and faster slop? Pablos Holman has spent his career living inside those questions. He is a hacker, inventor, venture capitalist, and founder of Deep Future, an invention capital firm backing the mad scientists, rogue engineers and maverick entrepreneurs trying to build technologies that actually matter. His career has touched everything from cryptocurrency in the 1990s and AI for financial markets to the early days of Blue Origin and the launch of Intellectual Ventures Lab, where the work included mosquito-killing lasers, malaria-diagnosing microscopes, vaccine coolers, advanced antennas and nuclear reactors powered by waste. His book, Deep Future - Creating Technology That Matters, argues that the next wave of innovation will not come from making software marginally more addictive. It will come from solving the physical, messy, expensive, essential problems that humanity depends on: energy, water, food, waste, construction, manufacturing, medicine and infrastructure. In this conversation, Pablos makes the case for optimism with teeth. Not optimism as a mood. Optimism as a discipline. A willingness to stare at massive problems without flinching… and then go build something. We talk about why software can’t save the world by itself, why energy may be the root problem behind almost everything, why AI’s most meaningful work may happen in science, and why the future belongs to people willing to work on problems big enough to scare everyone else. Enjoy the conversation…
- Running time: 1:04:47.
- Hello from beautiful Montreal.
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- Please visit and leave comments on the blog - Thinking With Mitch Joel.
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- Here is my conversation with Pablos Holman.
- Deep Future - Creating Technology That Matters.
- Check out Pablos on the Tim Ferriss Podcast: One of The Scariest Hackers I’ve Ever Met — Pablos Holman.
- Follow Pablos on LinkedIn.
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Chapters:
(00:00) - Introduction to Deep Future and Venture Capital.
(02:47) - The Shift from Software to Deep Tech.
(06:08) - Revolutionizing Manufacturing with Robotics.
(08:49) - The Environmental Impact of Energy Production.
(12:13) - Innovative Solutions for Energy Challenges.
(15:08) - The Role of AI in Scientific Advancements.
(17:53) - Cultural Shifts in Manufacturing and Education.
(20:55) - The Future of Energy and Nuclear Solutions.
(23:56) - The Importance of Long-Term Thinking.
(26:45) - Connecting Work to Meaning and Purpose.
(30:13) - The Role of Corporations in Infrastructure Investment.
(33:03) - The Future of Jobs in an Automated World.
(36:13) - AI’s Role in Solving Global Problems.
(39:01) - The Need for Optimism in Technology.
(41:59) - Final Thoughts and the Future of Humanity.