Open Letter To The NIH
Astral Codex Ten Podcast
You can sign the letter . The Trump administration has been , and people and groups with business before the administration have started laundering criticism through other sources with less need for goodwill. So I have been asked to share , which needs signatures from scientists, doctors, and healthcare professionals. The authors tell me (THIS IS NOT THE CONTENTS OF THE LETTER, IT’S THEIR EXPLANATION, TO ME, OF WHAT THE LETTER IS FOR): The NIH has spent at least than Congress has appropriated to them, which is bad because medical research is good and we want more of it. In May, that he...
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In Search Of AI Psychosis
Astral Codex Ten Podcast
AI psychosis (, ) is an apparent phenomenon where people go crazy after talking to chatbots too much. There are some high-profile anecdotes, but still many unanswered questions. For example, how common is it really? Are the chatbots really driving people crazy, or just catching the attention of people who were crazy already? Isn’t psychosis supposed to be a biological disease? Wouldn’t that make chatbot-induced psychosis the same kind of category error as chatbot-induced diabetes? I don’t have all the answers, so think of this post as an exploration of possible analogies and precedents...
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Your Review: Ollantay
Astral Codex Ten Podcast
Finalist #9 in the Review Contest [This is one of the finalists in the 2025 review contest, written by an ACX reader who will remain anonymous until after voting is done. I’ll be posting about one of these a week for several months. When you’ve read them all, I’ll ask you to vote for a favorite, so remember which ones you liked] Ollantay is a three-act play written in Quechua, an indigenous language of the South American Andes. It was first performed in Peru around 1775. Since the mid-1800s it’s been performed more often, and nowadays it’s pretty easy to find some company in Peru...
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My Responses To Three Concerns From The Embryo Selection Post
Astral Codex Ten Podcast
[original post ] #1: Isn’t it possible that embryos are alive, or have personhood, or are moral patients? Most IVF involves getting many embryos, then throwing out the ones that the couple doesn’t need to implant. If destroying embryos were wrong, then IVF would be unethical - and embryo selection, which might encourage more people to do IVF, or to maximize the number of embryos they get from IVF, would be extra unethical. I think a default position would be that if you believe humans are more valuable than cows, and cows more valuable than bugs - presumably because humans are more...
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Your Review: Dating Men In The Bay Area
Astral Codex Ten Podcast
Finalist #8 in the Review Contest [This is one of the finalists in the 2025 review contest, written by an ACX reader who will remain anonymous until after voting is done. I’ll be posting about one of these a week for several months. When you’ve read them all, I’ll ask you to vote for a favorite, so remember which ones you liked] I. The Men Are Not Alright Sometimes I’m convinced there’s a note taped to my back that says, “PLEASE SPILL YOUR SOUL UPON THIS WOMAN.” I am not a therapist, nor in any way certified to deal with emotional distress, yet my presence seems to cause people...
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In Defense Of The Amyloid Hypothesis
Astral Codex Ten Podcast
A guest post by David Schneider-Joseph The “amyloid hypothesis” says that Alzheimer’s is caused by accumulation of the peptide amyloid-β. It’s the leading model in academia, but a favorite target for science journalists, contrarian bloggers, and neuroscience public intellectuals, who point out problems like: Some of the research establishing amyloid's role turned out to be fraudulent. The level of amyloid in the brain doesn’t correlate very well with the level of cognitive impairment across Alzheimer’s patients. Several strains of mice that were genetically programmed to have...
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Highlights From The Comments On Liberalism And Communities
Astral Codex Ten Podcast
[Original post: ] 1: Comments About The Theory 2: Comments About Specific Communities 3: Other Comments Comments About The Theory Darwin : I think you may (*may*, I'm not sure) be vastly underestimating how many people are in some form of nontraditional tight-knit community. Notice that many of the communities you list are things you've directly personally encountered through your online interests or social circle. Most people have never heard of libertarian homesteaders or rationalist dating sites, perhaps you have also never heard of the things most other people belong to. For my part, I...
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Your Review: My Father’s Instant Mashed Potatoes
Astral Codex Ten Podcast
[This is one of the finalists in the 2025 review contest, written by an ACX reader who will remain anonymous until after voting is done. I’ll be posting about one of these a week for several months. When you’ve read them all, I’ll ask you to vote for a favorite, so remember which ones you liked] My dad only actually enjoys about ten foods, nine of them beige. His bread? White. His pizza? Cheese. His meat? Turkey breast. And his side dish? Mashed potatoes. As a child I hated mashed potatoes, despite his evangelization of them. I too was a picky eater growing up, but I would occasionally...
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Should Strong Gods Bet On GDP?
Astral Codex Ten Podcast
Slightly contra Fukuyama on liberal communities Francis Fukuyama is on Substack; last month he wrote . As always, read the whole thing and don’t trust my summary, but the key point is: R. R. Reno, editor of the magazine First Things, the liberal project of the past three generations has sought to weaken the “” of populism, nationalism, and religion that were held to be the drivers of the bloody conflicts of the early 20th century. Those gods are now returning, and are present in the politics of both the progressive left and far right—particularly the right, which is characterized...
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Your Review: Joan of Arc
Astral Codex Ten Podcast
Finalist #6 in the Review Contest [This is one of the finalists in the 2025 review contest, written by an ACX reader who will remain anonymous until after voting is done. I’ll be posting about one of these a week for several months. When you’ve read them all, I’ll ask you to vote for a favorite, so remember which ones you liked] When the prefect of Alexandria’s daughter converted to Christianity, nothing in particular happened - it wasn’t as though the laws outlawing the cult would be enforced against her. She was smart, she was pretty (beautiful, even) and she had connections. So...
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Table Of Contents
I. Comments About Master And Slave Morality
II. Comments By People Named In The Post
III. Comments Making Specific Points About One Of The Thinkers In The Post
IV. Other Comments
https://www.astralcodexten.com/p/highlights-from-the-comments-on-nietzsche