ImputePGTA and PGT-P Explained: The Latest in Polygenic Embryo Testing with guest Jonathan Anomaly of Herasight
Release Date: 11/12/2025
When IVF Fails: The 'What Now?' Moment and Finding Hope Through Donor Eggs with guest Victoria Nino
The Egg Whisperer Show
I am talking to the incredible Victoria Nino, author of Our Hearts Match, donor conception advocate, and mom of two about one of the most vulnerable moments in a fertility journey: what happens after IVF fails. Victoria has lived through multiple failed IVF cycles, stage three endometriosis, years of heartbreak, and ultimately became a mother twice over through donor egg conception via two very different paths. Her story is raw, honest, and full of the kind of hard-won wisdom that only comes from truly living it. We dive deep into the emotional rollercoaster of failed IVF cycles, the grief...
info_outline
Fertility Myths Debunked
The Egg Whisperer Show
Do you think you can put botox in your ovaries? You know, plump up those older eggs to regain their youthfulness? Nope, sorry. Not possible. Or have you thought that because you can take a youthful looking selfie, and feel great, that your fertility must be picture perfect too? Nope, sorry. Good selfies don’t equal good fertility. But you’re not dumb. You know that. But there may be some tricky information out there that you’re not entirely sure if it’s true. Fertility isn’t surface level. It’s not skin-deep. It’s biology. It’s what’s deep inside, and yet impacted by...
info_outline
Everything You've Ever Wanted to Ask an Embryologist with Lucy Lines
The Egg Whisperer Show
Lucy Lines began her career as an embryologist, starting at Monash IVF in Melbourne in 2001. She worked in fertility clinics around the world, and consulted in clinics throughout Europe, the UK, and Australia. She realized that in addition to creating babies, she also loves learning and helping people. Having faced infertility and IVF herself, she now works as an educator and coach for fertility patients. Her Instagram account is refreshing and informative, and I love that she says she will, "happily answer all the questions you've saved for the day you got to meet an embryologist." I've met...
info_outline
4 Step Guide to IVF (The Egg Whisperer D.I.E.T)
The Egg Whisperer Show
The “Egg Whisperer D.I.E.T.” covers the four things you need to know about IVF, and you can apply them to whatever your situation may be. D: Diagnosis (get your TUSHY checked: Tubes, Ultrasound of Uterus, Sperm, Hormones, and Your genetic profile) I: IVF E: Endometrial Receptivity T: Transfer Do you have questions about IVF, and what to expect? The next live class call is on Monday, April 20, 2026 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom. My Book, Dr. Aimee Eyvazzadeh is one of America’s most well known...
info_outline
Pros and Cons of IVF
The Egg Whisperer Show
It seems like everyone is doing IVF. You hear about it in the news. You hear about it in different articles. You hear about it from your neighbors, your friends, so many different people are doing IVF. Everyone is giving different bits of information, but what are you supposed to believe? Today I want to share about the risks of IVF so you know what you’re getting yourself into. IVF allows you to preserve embryos for the future, genetically test embryos, and it does offer the highest pregnancy rate of current fertility treatments. In this episode, I'm sharing: - The basics of IVF:...
info_outline
The Fertility Formula: Hormones, Inflammation, and the Truth About Optimizing Fertility with Dr. Natalie Crawford
The Egg Whisperer Show
In this episode, I'm joined by one of my favorite fellow fertility doctors - Dr. Natalie Crawford, a board-certified reproductive endocrinologist and infertility specialist, co-founder of Fora Fertility in Austin, Texas, host of the As a Woman podcast, and author of the brand-new book The Fertility Formula. Dr. Crawford's journey into reproductive medicine is deeply personal: after experiencing four pregnancy losses and feeling dismissed by the medical system, she channeled that pain into a career dedicated to making sure no patient ever feels unheard or uninformed. Her...
info_outline
How to Approach IVF Challenges with guest Dr John Norian
The Egg Whisperer Show
In this episode of The Egg Whisperer Show, I sit down with the incredible Dr. John Norian, a board-certified OB-GYN and Reproductive Endocrinologist with HRC Fertility in Pasadena and Rancho Cucamonga, California. Dr. Norian completed his residency at Albert Einstein College of Medicine, his fellowship at the NIH, and has served as a Lieutenant Commander in the U.S. Public Health Service, providing care to military families. He is a passionate advocate for anyone on a fertility journey, regardless of relationship status or anatomy. We dive deep into some of the most frustrating and complex...
info_outline
How to Create Your Own Personalized IVF Plan
The Egg Whisperer Show
Today on the podcast, I'm talking all about how you can create your own personalized IVF Plan. Have you ever used Google Maps and been redirected midway via a better route? Alternatively, maybe you’re proactive in managing traffic and go directly to Waze to get you from point A to point B in the most time effective way? These apps are well-loved and widely used because they remove obstacles out of an otherwise potentially painful process, and they do so with data. I bring the beauty of Google Maps into my fertility care by serving as a personal navigator for every one of my patient’s IVF...
info_outline
Secondary Infertility
The Egg Whisperer Show
Secondary infertility affects so many of my patients. In today’s podcast episode, I’m talking about what happens when someone has no trouble getting pregnant for baby number one and then struggles to conceive another child. People in this situation often don’t know what to do because this is so new to them. I’m sharing everything you need to know about secondary infertility: the causes, treatments, and some of my tips. The truth is, secondary infertility is overwhelming and upsetting. You want to make sure that you have people around that support you, so I also encourage you to share...
info_outline
New Technology in Egg and Embryo Freezing with guest Dr. Angie Beltsos
The Egg Whisperer Show
Today on The Egg Whisperer Show, I’m excited to have Dr. Angie Beltsos joining me to talk about new technology in egg and embryo freezing. She is now with Brown Fertility, and formerly the CEO of Vios Fertility Institute. This year, her practice announced that they would be the first to use new technology to freeze and store both eggs and embryos. TMRW Life Sciences offers new advancements for freezing, monitoring, and storing our most precious cells. We also talk about their upcoming app, and her background in fertility medicine. I am really honored to have her on to talk to her about...
info_outlineRead the full episode notes: https://www.draimee.org/imputepgta-and-pgt-p-explained-the-latest-in-polygenic-embryo-testing-with-guest-jonathan-anomaly-of-herasight
In our conversation, we unpack the science and ethics behind polygenic testing, discuss how it differs from traditional embryo screening, and address the hopes and concerns that come with these new technologies. We talk about the real-world impact for patients, the importance of informed consent, and how families can make empowered choices about their reproductive journeys. Whether you’re a patient, a provider, or just curious about the future of fertility medicine, this episode is packed with insights.
In this episode, we cover:
- The basics of PGTP and how it compares to PGTA and PGTM
- Announcement of ImputePGTA, a new technique that enables accurate polygenic embryo screening from a routine test (PGT-A)
- How polygenic risk scores are developed and validated
- The potential and limitations of predicting disease risk and traits in embryos
- Ethical considerations and common misconceptions about “designer babies”
- The role of family history and ancestry in genetic testing
- How Herasight’s technology can help patients with different backgrounds and needs
- What the future holds for embryo testing, including IVG and gene editing
Resources:
- Herasight: herasight.com
- Jonathan Anomaly’s website: jonathan-anomaly.com
- Dr. Aimee’s resources: draimee.org
- IVF calculator and white papers (available on herasight.com)
- Subscribe to the Egg Whisperer Show on YouTube and Spotify
Click here to join Dr. Aimee for The IVF Class.