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The Plastic Detox: Reducing Endocrine Disruptors for Better Fertility and Human Health with Shanna Swan & Sian Sutherland | RR 23

The Great Simplification with Nate Hagens

Release Date: 03/18/2026

Wide Boundary News: Sacrificing Wilderness, Oil Data Propaganda, and Feeding the Superorganism's Brain show art Wide Boundary News: Sacrificing Wilderness, Oil Data Propaganda, and Feeding the Superorganism's Brain

The Great Simplification with Nate Hagens

This week’s Frankly is another edition of Wide Boundary News, where Nate invites listeners to view the constant churn of headlines through a wider-boundary lens. He begins with the misleading framing of recent oil production statistics by the United States, which blurs distinctions between crude oil and broader petroleum products. Nate uses this as a case study in how data can be technically correct, yet structurally misleading – particularly when used for political storytelling. The lens widens as he considers whether the peak of the carbon pulse could pass without clear public...

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Why Each American Lives Like a 40-Ton Whale: Power, Overshoot, and Climate with Tad Patzek show art Why Each American Lives Like a 40-Ton Whale: Power, Overshoot, and Climate with Tad Patzek

The Great Simplification with Nate Hagens

Many of us were taught that humans have been the dominant force shaping the modern world through sheer grit, ingenuity, and innovation. While true to an extent, there are also deep, embedded laws of energy that have both constrained and enabled human cleverness and our influence over our surroundings. What exactly are these laws, and what happened in the past few centuries that allowed for an explosion of technology and consumption? Perhaps more importantly, how can that knowledge help us understand how the decades and centuries ahead might be different? In this episode, Nate is joined by...

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A Perspective From Lebanon: Who Will We Be When Things Get Hard? | Frankly 140 show art A Perspective From Lebanon: Who Will We Be When Things Get Hard? | Frankly 140

The Great Simplification with Nate Hagens

In this week’s Frankly, Nate steps away from analysis and reflects on a call that reframed his thinking. He shares a recent conversation with a close friend living in Lebanon, who amid ongoing daily violence and loss has been hosting displaced families and leading meditation practices in her community. Nate notes that her grounded presence, alongside the trust she carries from a centuries-old lineage in her village, reveals the ways in which social capital and contemplative practice can hold someone steady as the world around them changes. From that conversation, Nate distills the wider work...

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This War Changes Everything: Are We Ready for Energy Shockwaves From the Strait of Hormuz? with Rory Johnston show art This War Changes Everything: Are We Ready for Energy Shockwaves From the Strait of Hormuz? with Rory Johnston

The Great Simplification with Nate Hagens

Over three-quarters of the global population has never lived through a major global energy crisis, such as those of the 1970s. In early 2026, that is about to change as the world faces the largest energy disruption in history, measured by the daily loss of oil output. This crisis won’t be evenly distributed but will be felt everywhere – and is guaranteed to have ripple effects we won’t see coming. How much oil remains in circulation, and what level of damage has already been inflicted on our global energy infrastructure? In this episode, Nate is joined by oil market analyst Rory Johnston...

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How to Think About the Future (Part 2): Four Variables Shaping the Coming Decades | Frankly 139 show art How to Think About the Future (Part 2): Four Variables Shaping the Coming Decades | Frankly 139

The Great Simplification with Nate Hagens

This week’s Frankly is part two of the series How to Think About the Future. Today, Nate expands on the case for holding a distribution of possible futures rather than a single preferred one, and walks through a structured scenario-building exercise. He begins with the two-by-two grid that he has used for years, which indicates whether the economy will expand or contract and whether this happens within ecological limits or in overshoot. The four quadrants this produces represent possible directions toward the future: toward green growth, Mordor, Mad Max, or the Great Simplification. From...

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Wisdom in a World in Crisis: The Counterintuitive Need to Slow Down and Find Spaciousness with Iain McGilchrist show art Wisdom in a World in Crisis: The Counterintuitive Need to Slow Down and Find Spaciousness with Iain McGilchrist

The Great Simplification with Nate Hagens

For many of us, our instinctual response to rising conflict and instability might be to recede further into pragmatism as a way to survive. Yet, if our cultural values and ways of life are what got us here, rooted in narrow-boundary, cold, and logical thinking – then perhaps moments of turbulence like these actually call on us to change our way of thinking entirely. Is this moment our opportunity to pivot toward worldviews that emphasize the intangible qualities of life, and could that shift cause a cascade through our actions and decisions, leading to more balanced decision-making for the...

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How to Think About the Future (Part 1): Changing the Future Starts with How You Think | Frankly 138 show art How to Think About the Future (Part 1): Changing the Future Starts with How You Think | Frankly 138

The Great Simplification with Nate Hagens

In this week's Frankly, Nate opens a new series called How to Think About the Future. He begins with some comments he’s heard repeatedly on this platform: why cover nuclear, plastics, renewables, or climate when something else is the real issue? Nate observes that these questions come from people who have already settled on a single storyline about what's coming, and are filtering everything else through it. Our actual reality is much more complex and unknowable, and even the most well-informed perspectives may only be able to capture pieces of the bigger picture. Nate emphasizes that even...

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The Fantasy of Space Colonization: The Spaceship We're Already On with Tom Murphy & DJ White | RR 24 show art The Fantasy of Space Colonization: The Spaceship We're Already On with Tom Murphy & DJ White | RR 24

The Great Simplification with Nate Hagens

On the heels of Artemis II, our cultural obsession with space colonization continues, even as we face increasing global resource constraints and planetary health declines. Techno-optimists, including some of the wealthiest among us, dream of a future where we mine, travel to, and colonize other planets – all in the hopes of bypassing the problems we now face on Earth. But from the perspective of physics and ecology, how feasible is space colonization – and are these interplanetary ambitions blinding us to the miracle of the planetary spaceship we already inhabit? In this episode,...

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Oil 301: The World After Cheap Energy | Frankly 137 show art Oil 301: The World After Cheap Energy | Frankly 137

The Great Simplification with Nate Hagens

Today’s Frankly is the final installment in a three-part series on the role oil plays in modern civilization, prompted by the recent flow disruptions and geopolitical conflict surrounding the Strait of Hormuz. Nate frames the entire arc of this series through the concept of the carbon pulse: a one-time inheritance of ancient stored sunlight that humanity is burning through in a few hundred years. He highlights how modern economies, now roughly a thousand times larger than five centuries ago, are built on the assumption that the energy abundance at the top of this curve is permanent, when in...

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Oil 201: What Happens When the Oil Stops Flowing | Frankly 136 show art Oil 201: What Happens When the Oil Stops Flowing | Frankly 136

The Great Simplification with Nate Hagens

This week’s Frankly is the second in a three-part series on the role oil plays in modern civilization, prompted by the recent flow disruptions and geopolitical conflict surrounding the Strait of Hormuz. This installment explores how modern society has been built on the assumption of cheap and abundant energy, and what happens when that assumption breaks down. Nate describes the ways our built systems, including food production, water treatment, manufacturing, and global trade, are calibrated to cheap energy inputs, and how processes that look economically efficient are often deeply...

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More Episodes

The number of couples struggling to become pregnant due to unexplained infertility is growing at an alarming rate across the globe. Alongside this concerning rise is the growing awareness of how endocrine disrupting chemicals (EDCs) – particularly those found in plastics and personal care products – are negatively affecting our hormonal health and overall well-being. If we removed or reduced EDCs from the environments of couples struggling to conceive – dramatically reducing their exposure – is it possible their fertility would be improved? 

In this episode, Nate is joined by Dr. Shanna Swan, an award-winning scientist, and Sian Sutherland, a plastics expert, to discuss Shanna’s new Netflix documentary, titled The Plastic Detox, where she enacts a real-world ‘plastic intervention’ in the lives of six couples struggling with unexplained infertility – with the hope that they are able to get pregnant by the end of the study. Additionally, Sian shares the strategies her organization has been using to increase regulation of EDC-containing products and increase the availability of plastic-free options. Shanna and Sian also discuss how they’re bringing their work together for the Plastic Free Babies campaign, which emphasizes why avoiding toxic chemical exposure during the first one-thousand days of a baby’s life is so important to preventing generational effects on overall health and fertility. 

How might reducing our exposure to EDCs such as phthalates, bisphenols, and parabens improve markers of hormonal health and create ripple effects on our overall quality of life? What is the reasonable responsibility of our governments to test and regulate the safety of products on the market – and are our current institutions fulfilling those expectations? Finally, could addressing the toxins and pollution related to declining fertility lead us down a path of broader systemic change for the entire web of life? 

 

About Dr. Shanna Swan:

Dr. Shanna H. Swan, PhD, is an award-winning scientist based at Mt. Sinai (New York, NY). Shanna has published more than 200 scientific papers and has been featured in extensive media coverage around the world. She currently serves as the Director of the Action Science Initiative, a program that conducts rapid interventions and larger, longer-term studies that look at the impacts of environmental pollutants on fertility and related markers of reproductive health. Additionally, Shanna co-authored the 2021 book, Countdown: How Our Modern World Is Threatening Sperm Counts, Altering Male and Female Reproductive Development, and Imperiling the Future of the Human Race. 

Most recently, Shanna was featured in the documentary, The Plastic Detox, where she helped six couples dealing with unexplained fertility reduce their exposure to endocrine disrupting chemicals in their environment in hopes of getting pregnant. The movie was released on Netflix on March 16th, 2026. Shanna’s previous appearances include ABC News, NBC Nightly News, 60 Minutes, CBS News, PBS, BBC, PRI Radio, NPR, Andrew Huberman Lab, and The Joe Rogan Experience. 

 

About Sian Sutherland:

Sian Sutherland is Co-founder of A Plastic Planet, one of the most recognized and respected organizations tackling the plastic crisis. More recently, she also co-founded PlasticFree, the first materials and systems solutions platform, empowering the 160m global creatives to design waste out at the source. Sian was awarded the Female Marketer of the Year, Entrepreneur of the Year, and British Inventor of the Year. In 2023 at the UN Plastics Treaty negotiations (INC2), in partnership with Plastic Soup Foundation, A Plastic Planet launched the Plastic Health Council, bringing expert scientists to the negotiating process with the irrefutable proof of plastic chemicals’ impacts on human health. 

Most recently, in early 2024, Sian co-founded the Foundation for Visionary Science and Art with Alex Adams, working with the scientists to help fund their extraordinary research work on psychedelic therapies. Passionately pro-business and solutions focused, Sian believes the plastic crisis gives mankind a rare gateway to change both materials and systems to create a different future for next generations.

 

Show Notes and More

 

Watch this video episode on YouTube

 

Want to learn the broad overview of The Great Simplification in 30 minutes? Watch our Animated Movie.

 

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