The Plastic Detox: Reducing Endocrine Disruptors for Better Fertility and Human Health with Shanna Swan & Sian Sutherland | RR 23
The Great Simplification with Nate Hagens
Release Date: 03/18/2026
Oil 301: The World After Cheap Energy | Frankly 137
The Great Simplification with Nate Hagens
Today’s Frankly is the final installment in a three-part series on the role oil plays in modern civilization, prompted by the recent flow disruptions and geopolitical conflict surrounding the Strait of Hormuz. Nate frames the entire arc of this series through the concept of the carbon pulse: a one-time inheritance of ancient stored sunlight that humanity is burning through in a few hundred years. He highlights how modern economies, now roughly a thousand times larger than five centuries ago, are built on the assumption that the energy abundance at the top of this curve is permanent, when in...
info_outline
Oil 201: What Happens When the Oil Stops Flowing | Frankly 136
The Great Simplification with Nate Hagens
This week’s Frankly is the second in a three-part series on the role oil plays in modern civilization, prompted by the recent flow disruptions and geopolitical conflict surrounding the Strait of Hormuz. This installment explores how modern society has been built on the assumption of cheap and abundant energy, and what happens when that assumption breaks down. Nate describes the ways our built systems, including food production, water treatment, manufacturing, and global trade, are calibrated to cheap energy inputs, and how processes that look economically efficient are often deeply...
info_outline
Oil 101: What You Actually Need to Know About Oil | Frankly 135
The Great Simplification with Nate Hagens
This week’s Frankly is the first in a three-part series on the role oil plays in modern civilization, prompted by the recent flow disruptions and geopolitical conflict surrounding the Strait of Hormuz. This initial installment covers some foundational concepts of The Great Simplification platform, including what oil actually is, what it does for us, and why most of us never see any of it. Nate begins by describing how oil formed from the compression of ancient marine phytoplankton over millions of years, framing it as a solar battery that took geological time to charge and that humans are...
info_outline
Navigating the Metacrisis: Finding Calm in the Storm through Awareness and Meditation with Sam Harris
The Great Simplification with Nate Hagens
Between global crises and personal problems, modern life is overflowing with things to worry about, including many issues that feel too big to even address. Yet, our ability to influence these problems and how much we worry about them are not equal to each other – and in fact, getting lost in thoughts of anxiety can reduce our ability to act. Given the direct line between individual inner states and civilizational dysfunction, what global change might be possible if we train ourselves to observe thought, rather than be unconsciously consumed and paralyzed by it? In this episode, Nate is...
info_outline
Uncomfortable Questions for Unsettled Times: A World at the Edge of Change | Frankly 134
The Great Simplification with Nate Hagens
This week's Frankly is another in a recurring series, Uncomfortable Questions in Unsettled Times, where Nate poses questions about our shared future. Today he focuses on the unfolding crisis in the Persian Gulf, unpacking hidden implications that aren’t covered by the headlines. Nate opens by examining how behind-the-scenes geopolitical decisions at the highest level create a widespread ripple effect – influencing everything from oil production to water desalination to fertilizer and food systems. He considers the risk of continued geopolitical conflict as global alliances shift, as well...
info_outline
Scrambling for Energy Security: Navigating Unstable Energy Supplies Amidst Global Conflict with Chris Keefer
The Great Simplification with Nate Hagens
As the war in Iran creates chaos in every domain of life, the already-fragile energy systems of many countries find themselves on the brink of crisis after spending decades investing in natural gas infrastructure, largely supplied by Middle Eastern countries. With projected natural gas prices now spiking across the world, a growing number of nations are re-prioritizing energy security over energy convenience – calling into question the types of electricity generation needed for their citizens as they look to the coming decades. Could this lead to calls for a nuclear power revival in the...
info_outline
Iran, U.S., and the Rest: The Unavoidable Pig in the Python | Frankly 133
The Great Simplification with Nate Hagens
In this episode, Nate offers a personal reflection on the unfolding geopolitical tensions surrounding the Strait of Hormuz, beginning with an examination of how disruptions to fossil fuel flows propagate through the global economy, but with a time lag. He points out how many of the world’s countries rely heavily on imported fossil fuels, as well as the potential impact on California’s already high gas prices. Nate also contrasts the relative insulation of those in the United States with the far greater exposure of those living in Asia, Europe, and Africa, outlining how second- and...
info_outline
Ending the AI Arms Race: Why Safer Futures Are Still Possible & What You Can Do to Help with Tristan Harris
The Great Simplification with Nate Hagens
The conversation around artificial intelligence has been captured by two competing narratives – techno-abundance or civilizational collapse – both of which sidestep the question of who this technology is actually being built for. But if we consider that we are setting the initial conditions for everything that follows, we might realize that we are in a pivotal moment for AI development which demands a deeper cultural conversation about the type of future we actually want. What would it look like to design AI for the benefit of the 99%, and what are the necessary steps to make that...
info_outline
What to Do as the World Falls Apart: A Framework for Action | Frankly 132
The Great Simplification with Nate Hagens
This week’s Frankly marks a turning point in the work of The Great Simplification. Having spent twenty years articulating the more-than-human predicament, Nate shifts from diagnosis to direction as current events – including conflict in the Strait of Hormuz – accelerate the timeline. Today Nate shares a first-pass framework for action and response that’s organized around what to do now, which could be applied to various places and at multiple scales. The framework begins with a personal foundation of inner work: stabilizing the nervous system, recapturing a sense of agency, doing...
info_outline
The Plastic Detox: Reducing Endocrine Disruptors for Better Fertility and Human Health with Shanna Swan & Sian Sutherland | RR 23
The Great Simplification with Nate Hagens
The number of couples struggling to become pregnant due to unexplained infertility is growing at an alarming rate across the globe. Alongside this concerning rise is the growing awareness of how endocrine disrupting chemicals (EDCs) – particularly those found in plastics and personal care products – are negatively affecting our hormonal health and overall well-being. If we removed or reduced EDCs from the environments of couples struggling to conceive – dramatically reducing their exposure – is it possible their fertility would be improved? In this episode, Nate is joined by Dr....
info_outlineThe number of couples struggling to become pregnant due to unexplained infertility is growing at an alarming rate across the globe. Alongside this concerning rise is the growing awareness of how endocrine disrupting chemicals (EDCs) – particularly those found in plastics and personal care products – are negatively affecting our hormonal health and overall well-being. If we removed or reduced EDCs from the environments of couples struggling to conceive – dramatically reducing their exposure – is it possible their fertility would be improved?
In this episode, Nate is joined by Dr. Shanna Swan, an award-winning scientist, and Sian Sutherland, a plastics expert, to discuss Shanna’s new Netflix documentary, titled The Plastic Detox, where she enacts a real-world ‘plastic intervention’ in the lives of six couples struggling with unexplained infertility – with the hope that they are able to get pregnant by the end of the study. Additionally, Sian shares the strategies her organization has been using to increase regulation of EDC-containing products and increase the availability of plastic-free options. Shanna and Sian also discuss how they’re bringing their work together for the Plastic Free Babies campaign, which emphasizes why avoiding toxic chemical exposure during the first one-thousand days of a baby’s life is so important to preventing generational effects on overall health and fertility.
How might reducing our exposure to EDCs such as phthalates, bisphenols, and parabens improve markers of hormonal health and create ripple effects on our overall quality of life? What is the reasonable responsibility of our governments to test and regulate the safety of products on the market – and are our current institutions fulfilling those expectations? Finally, could addressing the toxins and pollution related to declining fertility lead us down a path of broader systemic change for the entire web of life?
About Dr. Shanna Swan:
Dr. Shanna H. Swan, PhD, is an award-winning scientist based at Mt. Sinai (New York, NY). Shanna has published more than 200 scientific papers and has been featured in extensive media coverage around the world. She currently serves as the Director of the Action Science Initiative, a program that conducts rapid interventions and larger, longer-term studies that look at the impacts of environmental pollutants on fertility and related markers of reproductive health. Additionally, Shanna co-authored the 2021 book, Countdown: How Our Modern World Is Threatening Sperm Counts, Altering Male and Female Reproductive Development, and Imperiling the Future of the Human Race.
Most recently, Shanna was featured in the documentary, The Plastic Detox, where she helped six couples dealing with unexplained fertility reduce their exposure to endocrine disrupting chemicals in their environment in hopes of getting pregnant. The movie was released on Netflix on March 16th, 2026. Shanna’s previous appearances include ABC News, NBC Nightly News, 60 Minutes, CBS News, PBS, BBC, PRI Radio, NPR, Andrew Huberman Lab, and The Joe Rogan Experience.
About Sian Sutherland:
Sian Sutherland is Co-founder of A Plastic Planet, one of the most recognized and respected organizations tackling the plastic crisis. More recently, she also co-founded PlasticFree, the first materials and systems solutions platform, empowering the 160m global creatives to design waste out at the source. Sian was awarded the Female Marketer of the Year, Entrepreneur of the Year, and British Inventor of the Year. In 2023 at the UN Plastics Treaty negotiations (INC2), in partnership with Plastic Soup Foundation, A Plastic Planet launched the Plastic Health Council, bringing expert scientists to the negotiating process with the irrefutable proof of plastic chemicals’ impacts on human health.
Most recently, in early 2024, Sian co-founded the Foundation for Visionary Science and Art with Alex Adams, working with the scientists to help fund their extraordinary research work on psychedelic therapies. Passionately pro-business and solutions focused, Sian believes the plastic crisis gives mankind a rare gateway to change both materials and systems to create a different future for next generations.
Watch this video episode on YouTube
Want to learn the broad overview of The Great Simplification in 30 minutes? Watch our Animated Movie.
---
Support The Institute for the Study of Energy and Our Future
Join our Hylo channel and connect with other listeners