Episode 65: Regional differences in primary graft dysfunction
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Joan Guzmán-Bofarull, and senior author, Marta Farrero, both of the Hospital Clinic de Barcelona in Spain. They join to discuss their paper, “.” The discussion explores: The international consortium on PGD, the composition of the study, and the practices of the included countries in the United States, Canada, and Europe Hypotheses on why the study shows better 30-day and 1-year outcomes in the United States Considerations transplant centers can take regarding recipient management and donor heart selection...
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Episode 65: Refining the grading of mild CAV
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Nikil Prasad, MD, a cardiology fellow in the Columbia University Medical Center in New York, to discuss the paper, “.” The discussion explores: The study's subdivisions of CAV grade 1 into CAV 1a and CAV 1b, based on the degree of coronary stenosis Differing clinical information provided by different methods of CAV screening: reduced myocardial blood flow reserve vs angiographic grading Limitations in implementing PET-based CAV assessments at various centers, and how transplant programs can use combined...
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Episode 64: A look back at ISHLT2025
JHLT: The Podcast
On this special episode of JHLT: The Podcast, the Digital Media Editors take a look back at the exciting science that was on display at ISHLT2025, the ISHLT 45th Annual Meeting & Scientific Sessions. Topics include: Telomere biology disorders and lung transplantation The meeting's special focus on cardiogenic shock The apixiVAD trial exploring low dose apixaban in HeartMate 3 LVADs Myocardial recovery on durable LVADs For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . of the meeting can also be found at the JHLT website....
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Episode 63: Severe PGD Using DCD Hearts
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Peter Cho and senior author Abbas Ardehali, MD, to discuss the paper, “.” Peter is a third year medical student at Drexel University, and Dr. Ardehali is professor of surgery and medicine and the Director of the Heart, Lung, and Heart-Lung Transplant programs at UCLA. The episode explores: The study's findings regarding an increased incidence of severe PGD at 24 hours post-transplant in DCD over DBD recipients What risks weren't changed in DCD recipients—suggesting that DCD PGD is likely to be transient,...
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Episode 62: Apixaban Plasma Levels in Patients with HeartMate 3
JHLT: The Podcast
Returning for a second study this month, the JHLT Digital Media Editors invite first author Charlotte Van Edom to discuss the paper, “.” As a cardiologist in training and a PhD candidate at the University Hospitals Leuven in Belgium, Van Edom’s work focuses on hemocompatibility and mechanical circulatory support, covering both short-term and long-term support. The episode explores: The evolution of the use and understanding of direct oral anticoagulants (DOACs) during LVAD support, including the increased focus on Factor Xa inhibitors Encouraging findings from the study and what...
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Episode 61: Is Sotatercept safe in patients with PAH?
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite author Ioana Preston, MD, to discuss the paper, “.” Dr. Preston is the director of the pulmonary hypertension center at Lahey Hospital and Medical Center in Burlington, Massachusetts, and has over 20 years of experience in caring for patients with PH, as well as multiple clinical trials in PH. The episode explores: What makes sotatercept unique as the first “biologic” in the treatment of PAH Hypotheses about the mechanism of action in sotatercept Sotatercept’s interaction with mPAP and what it...
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Episode 60: Riociguat in patients with PAH and Cardiometabolic Comorbidities
JHLT: The Podcast
Returning for a second study this month, the JHLT Digital Media Editors conduct an internal discussion on the paper, “.” The episode explores: The aging PAH population and the new comorbidities that must be considered in research How the study augments and expands on recent standards, like the 2022 ESC/ERS guidelines for pulmonary hypertension Limitations on the study and opportunities for future research For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Those on lung transplant teams should check the previous...
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Episode 59: Rewarming Ischemia Time in Lung Transplantation
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite lead author Jan Van Slambrouck, MD, to discuss the paper, “.” Dr. Van Slambrouck is a general surgeon who’s just finished his PhD training at the KU Leuven lab of respiratory disease and thoracic surgery in Belgium. The episode explores: How rewarming ischemia time (RIT) affects donor lungs, especially on the molecular level The pace of rewarming and how prior literature prepared the team to track and evaluate it Clinical strategies to reduce RIT and directly address molecular changes For...
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Episode 58: Sympathetic Reinnervation
JHLT: The Podcast
Returning for a second study this month, the JHLT Digital Media Editors invite lead author Oliver J.F. Weiner, to discuss the paper, “.” Dr. Weiner is currently an out of training registrar at Monash Health in Melbourne, Australia, but will soon return to his home of the UK to begin internal medicine training with the intention becoming a cardiologist. He is especially interested in advanced heart failure and electrophysiology. The episode explores: The uncertainty around clinical influences on reinnervation The importance of this single-center study in expanding the literature Potential...
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Episode 57: Trends and Outcomes in EVLP
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite lead author Jonathan E. Williams, MD, to discuss the paper, “.” Dr. Williams is a general surgery resident at the University of Michigan in Ann Arbor, with work focusing on contemporary lung preservation strategies, perfusion techniques, and particularly, EVLP. The episode explores: How the study explores the theory that EVLP use may increase transplant volumes Preserving data quality and other study limitations How to work in fields of study that sometimes yield as many questions as answers For the latest studies...
info_outlineOn the second August episode of JHLT: The Podcast, the Digital Media Editors discuss a paper from the August issue of JHLT, entitled “A modular simulation framework for organ allocation.”The episode is hosted by Digital Media Editor Erika Lease, MD, FCCP, a transplant pulmonologist from the University of Washington.
The guests for this episode are first author Johnie Rose, MD, PhD, of the Center for Community Health Integration at Case Western Reserve University School of Medicine, and lead author Maryam Valapour, MD, MPP, of the Department of Pulmonary Medicine at the Cleveland Clinic.
In the episode, Drs. Rose and Valapour share the findings from their study, and tackle questions about the limitations of simulation models, what makes their COMET model different from past Simulation Allocation Models (SAMs), and why they made the project open-source.
Follow along at www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.