JHLT: The Podcast
The Journal of Heart and Lung Transplantation podcast airs each month and features the JHLT Digital Media Editors in round table talks with the Journal's contributors.
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Episode 88: Looking Back: Is Sotatercept Safe in Patients with PAH?
07/15/2026
Episode 88: Looking Back: Is Sotatercept Safe in Patients with PAH?
In case you missed it, JHLT: The Podcast is re-releasing a past audience favorite for your listening pleasure. This month, we revisit a conversation regarding a study from the April 2025 issue of JHLT about the . This conversation with Ioana Preston, MD, of the Tufts University School of Medicine in Boston, explores: What makes sotatercept unique as the first “biologic” in the treatment of PAH Hypotheses about the mechanism of action in sotatercept Sotatercept’s interaction with mPAP and what it indicates about the drug’s action on the pulmonary vasculature For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 87: The Trifecta Heart Study: Assessing Donor Specific Antibodies in AMR
07/01/2026
Episode 87: The Trifecta Heart Study: Assessing Donor Specific Antibodies in AMR
JHLT: The Podcast returns for July with a paper entitled “,” available online now and in the July print issue of JHLT. Today’s guests are first author Katelynn S. Madill-Thomsen, PhD and senior author Philip F. Halloran, MD, PhD, both from the Alberta Transplant Applied Genomics Center in Canada. In the episode, the authors and editors discuss: Striking similarities—and key differences—in the DSA-negative and DSA-positive groups Changes to clinical practice based on the findings, including innovations from the kidney transplant community Future studies, including tools and therapies that could be explored for improved clinical outcomes For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 86: A Patient Perspective on Ghost Coverage and Access to Immunosuppressants
06/17/2026
Episode 86: A Patient Perspective on Ghost Coverage and Access to Immunosuppressants
For the first time, JHLT: The Podcast welcomes a patient onto the podcast. The Digital Media Editors are pleased to welcome heart transplant recipient and patient advocate Payton Herres for a discussion about her in JHLT. In this compelling, moving discussion, Payton shares: Her treatment story—from her congenital diagnoses to her life-changing transplant—and her donor's story The difference between coverage and access—and how FDA labeling affected her access to an important component of her care What she wishes clinicians understood about long-term care of transplant patients For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 85: Assessing SCAI Shock Classification in Post-Cardiotomy Patients
06/03/2026
Episode 85: Assessing SCAI Shock Classification in Post-Cardiotomy Patients
On JHLT: The Podcast, we kick off June with a paper entitled “,” which is available online now and in the June issue of JHLT. Today’s guests are first author Ufuk Baldan, MD and senior author Patrick Klein, MD, PhD, both of the Amsterdam University Medical Center in the Netherlands. We discuss: The heterogeneous nature of post-cardiotomy shock and challenges to treat Should serial assessments become standardized post-cardiac surgery? Does SCAI staging overestimate risk—and how do we interpret the stages we observe immediately post-op? What's next for this line of research? For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 84: What Was Hot at ISHLT2026
05/20/2026
Episode 84: What Was Hot at ISHLT2026
On this special episode of JHLT: The Podcast, the Digital Media Editors take a look back at the exciting science that was on display at ISHLT2026, the ISHLT 46th Annual Meeting & Scientific Sessions. Topics include: Artificial intelligence and machine learning in transplantation, especially in assessing donor lungs and EVLP Cardiogenic Shock science at ISHLT2026, including a well-attended, all-new Academy The re-launch of the ISHLT International Thoracic Organ Transplant Registry, and the recent report in JHLT For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 83: Consensus on Graft Dysfunction within 72 Hours After Heart Transplant
05/06/2026
Episode 83: Consensus on Graft Dysfunction within 72 Hours After Heart Transplant
JHLT: The Podcast starts May with an important ten-year update to a keystone document—the “.” The consensus summary—and a —appears in the May issue of JHLT, and is . The podcast is happy to host conference leader and first author Jon Kobashigawa, MD, Cedars-Sinai in Los Angeles, to talk about the consensus document, the conference, and PGD. The conversation includes discussion of: Why the document needed updating and how consensus was achieved The revised severity scale for PGD and the omission of the vasoactive-inotropic score Changes from the old document, including: Newer predictors of PGD The latest donor preservation devices Updated treatment approaches For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 82: JHLT Special Issue: Device Therapies
04/30/2026
Episode 82: JHLT Special Issue: Device Therapies
In this episode, JHLT: The Podcast highlights a that’s just been released. The issue focuses on innovations in Device Therapies, and was edited by JHLT Deputy Editor Manreet Kanwar, MD, FACC, of the University of Chicago. Dr. Kanwar joins Digital Media Editor Van-Khue Ton, MD, PhD for a discussion about the special issue. The discussion explores: The importance of discussing device therapies in the advanced heart and lung failure communities The most anticipated device therapies in the pipeline for clinicians and patients to consider The impact of publishing in JHLT For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Read the special issue or . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 81: Lung Cancer after Lung Transplant
04/01/2026
Episode 81: Lung Cancer after Lung Transplant
JHLT: The Podcast kicks off April with a discussion of the paper, “,” which appears in the April issue of JHLT. Senior author Pauline Pradère, MD, of Hôpital Marie Lannelongue in Paris, joins the episode to talk about the paper. The conversation includes discussion of: The overall survival of patients who develop lung cancer after lung transplant—and the key differences between the cohort of patients who developed cancer versus the patients who did not Managing lung cancer in transplant recipients Immunosuppression in these patients, and other potential changes to clinical practice derived from the study For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 80: Solid Organ Transplantation and HIV Infection
03/18/2026
Episode 80: Solid Organ Transplantation and HIV Infection
JHLT: The Podcast continues a themed month on HIV infection in solid organ transplant, building on our last episode’s exploration from Dr. Saeed at Montefiore in New York. Our guest this episode is infectious diseases expert Cameron Wolfe, MD, Professor of Medicine at Duke University Medical Center. He joined us while on sabbatical with his family in Brisbane Australia for a conversation about how transplant centers now consider HIV infection, including transplant recipients who are HIV positive. The discussion explores: How the HOPE Act of 2013 changed practice in the United States, and how other countries have handled HIV transplantation regulations Immunosuppresion, antiviral therapy, and opportunistic infection in HIV+ transplant recipients Whether organ-specific surveillance changes in HIV+ patients The ethics of using organs from HIV+ donors and ensuring HIV+ patients are treated equitably For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at .
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Episode 79: Early Experience in Heart Transplantation Using Donors with HIV
03/04/2026
Episode 79: Early Experience in Heart Transplantation Using Donors with HIV
This month on JHLT: The Podcast, the Digital Media Editors host two themed discussions around HIV in solid organ transplantation. The conversation begins with a discussion of the paper, “,” which appears in the March issue of JHLT. First author Omar Saeed, MD, MSc, of the Division of Cardiology at Montefiore Medical Center in New York, NY USA, joins the episode. The conversation includes discussion of: The ethics and evolution of the Montefiore program's transplant eligibility and criteria The role of the HOPE Act in the changes to the program Superinfection, viral strain analysis, and informed consent of organ recipients Long-term patient follow upsa nd how other centers can begin this research For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Return later this month for a broader conversation with an infectious diseases expert about HIV in transplantation. Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 78: Barriers and Opportunities in DCD Heart Transplantation
02/18/2026
Episode 78: Barriers and Opportunities in DCD Heart Transplantation
JHLT: The Podcast returns with an episode for our heart transplant colleagues, discussing the paper, “,” from the February issue of JHLT. Featured on this episode is first author, Katherine G. Phillips, MD, of the Department of Cardiothoracic Surgery at NYU Langone, and co-author, Brian Wayda, MD, from the Division of Cardiology at NYU Langone. The discussion explores: Geographic variability on DCD heart utilization—why it happens and how to address Concerns around donor progression to circulatory arrest after life support withdrawal The volume of DCD hearts not utilized each year—and the gap between those successfully transplanted For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 77: ISHLT Consensus Statement: Short Telomere Syndrome and Lung Transplantation
02/04/2026
Episode 77: ISHLT Consensus Statement: Short Telomere Syndrome and Lung Transplantation
In this episode of JHLT: The Podcast, the Digital Media Editors host a discussion on a new consensus statement from ISHLT on . The document was first published last month. They’re joined by document leads Andrew Courtwright, MD, PhD, of the University of Pennsylvania in Philadelphia; Dr. John Mackintosh of Prince Charles Hospital in Brisbane; and John McDyer, MD, of the University of Pittsburgh Medical Center in Pittsburgh. The conversation includes discussion of: Recommendations for assessing patients for STS Which patients we should screen How the diagnosis influences transplant decision making and risk assessment How STS impacts immunosuppression Extrapulmonary comorbidities Future areas for research ISHLT are open to all at ISHLT.org. For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Return later this month for a conversation on barriers and opportunities in utilizing DCD hearts in transplantation. Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 76: Evolocumab’s Impact on Coronary Physiology and Microstructure in De Novo Heart Transplant Recipients
01/21/2026
Episode 76: Evolocumab’s Impact on Coronary Physiology and Microstructure in De Novo Heart Transplant Recipients
JHLT: The Podcast returns with an episode discussing the paper, “,” from the January issue of JHLT. Featured on this episode is early career guest host Bin Yang, MD, of Massachusetts General Hospital. Mentored by Digital Media Editor Van-Khue Ton, MD, PhD, Dr. Yang shares hosting duties this episode and brings great questions to the discussion. Drs. Yang and Ton are joined by the first author, Salma Karim, and senior author, Hans Eiskjaer, both from Aarhus University Hospital in Denmark. The discussion explores: What imaging and physical markers the researchers used to determine if evolocumab was influencing the development of cardiac allograft vasculopathy (CAV) The potential role of lipid-lowering therapies or statins in treating CAV The relationship between CAV and microvascular resistance (IMR) For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . In case you missed it, earlier this month the JHLT Digital Media Editors recapped their favorite papers from 2025. Take a listen! Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 75: A Look Back on 2025 in JHLT
01/07/2026
Episode 75: A Look Back on 2025 in JHLT
Happy new year and welcome to a new season of JHLT: The Podcast! In this year-end recap, the Digital Media Editors will each share one of their favorite studies from The Journal of Heart and Lung Transplantation in 2025. You’ll get a look at some of the best science in advanced heart and lung failure from the past year. Studies featured: Gomberg-Maitland M, et al. JHLT Apr 2025 44(4):609 – 624. Lefkowitz DS, et al. JHLT Apr 2025 44(4):487-502. Hollis P, et al. JHLT Dec 2025 44(12):1910-1917. Todurov B, et al. JHLT Nov 2025 44(11):1728-1734. For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 74: Outcomes for CTEPH patients with High Antiphospholipid Antibodies after Pulmonary Endarterectomy
12/17/2025
Episode 74: Outcomes for CTEPH patients with High Antiphospholipid Antibodies after Pulmonary Endarterectomy
JHLT: The Podcast returns with an episode discussing the paper, “,” from the December issue of JHLT. They are joined by the first author, Camille Miard, MD, and senior author, François Stéphan, MD, PhD, both from the cardiothoracic intensive care unit at Hôpital Marie Lannelongue in Paris. The discussion explores: Whether antiphospholipid antibody titers could predict postoperative outcomes for CTEPH patients undergoing pulmonary endarterectomy (PEA) How APS patients differed from non-APS patients in the PEA cohort The changes in clinical practice at Marie Lannelongue after the study's findings For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 73: Lung Transplant in Patients with Suspicious Lung Lesions
12/03/2025
Episode 73: Lung Transplant in Patients with Suspicious Lung Lesions
On this episode of JHLT: The Podcast, the Digital Media Editors host a discussion on the paper, “,” which appears in the December issue of JHLT. They are joined by the senior author, Stefan Schwarz, MD, PhD, of the Department of Thoracic Surgery at the Medical University of Vienna. The discussion explores: Methods used to assess the probability of malignancy in the patient cohort The limitations of common scanning methods in assessing this type of transplant patient What the study confirms or changes about standards in clinical practice For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 72: Impact of Donor-Specific Antibodies on Longitudinal Lung Function and BLAD
11/05/2025
Episode 72: Impact of Donor-Specific Antibodies on Longitudinal Lung Function and BLAD
On this episode of JHLT: The Podcast, the Digital Media Editors host a discussion on the paper, “.” They are joined by the first author, Muhtadi Alnababteh, MD, Assistant Professor at the University of Maryland and Staff Clinician at the National Institutes of Health, and senior author Michael Keller, MD, of the Pulmonary and Critical Care division at the University of Maryland. The discussion explores: Common characteristics of patients who developed donor-specific antibodies (DSA) Differences in outcomes depending on when DSA developed Associations between the development of DSA and antibody-mediated rejection, and related time frames For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 71: Cardiogenic Shock Working Group: Patients on Impella 5.5 for more than 14 days
10/15/2025
Episode 71: Cardiogenic Shock Working Group: Patients on Impella 5.5 for more than 14 days
On this episode of JHLT: The Podcast, the Digital Media Editors invite co-lead author Nir Uriel, MD, Director of Advanced Heart Failure and Cardiac Transplantation at New York Presbyterian Hospital and Professor of Medicine at Columbia University. Dr. Uriel joins to discuss the work of the Cardiogenic Shock Working Group (CSWG) and their recent paper, “.” The discussion explores: Why patients on longer duration of MCS had better survival but maintained similar rates of serious adverse events (SAEs) Why the study might show fewer SAEs than the literature historically shows How temporary MCS devices are selected in clinical settings in patients with cardiogenic shock The ongoing and upcoming activities of CSWG For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 70: Passive Leg Raise and Occult HFpEF in Pulmonary Hypertension
10/01/2025
Episode 70: Passive Leg Raise and Occult HFpEF in Pulmonary Hypertension
On this episode of JHLT: The Podcast, the Digital Media Editors invite author Dr. Ayumi Goda, from the Kyorin University Hospital in Tokyo, Japan, to discuss her team’s paper, “.” The discussion explores: How clinical observations led to the idea for a study on whether the passive leg raise could unmask occult HFpEF The potential diagnostic value of the passive leg raise in differing patient populations Age-specific cutoffs that may influence what kind of testing to use in clinical practice For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 69: Optimal Pre-Transplant Duration with HeartMate III LVADs
09/03/2025
Episode 69: Optimal Pre-Transplant Duration with HeartMate III LVADs
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Ahmet Bilgili, from the University of Florida’s Congenital Heart Center, and senior author Eric I. Jeng, MD, from the University of Florida’s MCS program. Bilgili and Dr. Jeng discuss their paper, “.” The discussion explores: Prior gaps in the literature regarding contemporary HM3 outcomes in relation to transplantation—and the study's potential influence on policy Which length of HM3 support influenced better post-transplant outcomes—and which ages were most influenced How these findings might change standard practice For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 68: DCD lung procurement in the UK
08/20/2025
Episode 68: DCD lung procurement in the UK
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Luke Williams, a cardiothoracic surgery trainee at Royal Papworth Hospital, NHS Blood and Transplant Clinical Research Fellow, and a PhD student at Cambridge University in the UK. Luke discusses his paper, “.” The discussion explores: Requirements, regulations, and practices in the UK around DCD procurement and A-NRP How survival rates differ and what they might imply about primary graft dysfunction in DCD versus DBD Further work planned in the area in the UK and throughout Europe For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 67: Metabolic and transcriptomic insights into temperature-controlled donor heart transportation
08/06/2025
Episode 67: Metabolic and transcriptomic insights into temperature-controlled donor heart transportation
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Gaurav Sharma, PhD, MBA, from the University of Texas Southwestern Medical Center in Dallas. Dr. Sharma discusses his paper, “.” The discussion explores: How donor hearts not offered or declined for transplantation responded in hypothermic preservation versus conventional static cold storage Potentially beneficial genetic signatures yielded by TCHP versus cold storage The surprising response of energy stores in the hearts to the different storage environments How multi-omic approaches could be applied to other organs For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 65: Regional differences in primary graft dysfunction
07/02/2025
Episode 65: Regional differences in primary graft dysfunction
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Joan Guzmán-Bofarull, and senior author, Marta Farrero, both of the Hospital Clinic de Barcelona in Spain. They join to discuss their paper, “.” The discussion explores: The international consortium on PGD, the composition of the study, and the practices of the included countries in the United States, Canada, and Europe Hypotheses on why the study shows better 30-day and 1-year outcomes in the United States Considerations transplant centers can take regarding recipient management and donor heart selection For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 65: Refining the grading of mild CAV
06/19/2025
Episode 65: Refining the grading of mild CAV
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Nikil Prasad, MD, a cardiology fellow in the Columbia University Medical Center in New York, to discuss the paper, “.” The discussion explores: The study's subdivisions of CAV grade 1 into CAV 1a and CAV 1b, based on the degree of coronary stenosis Differing clinical information provided by different methods of CAV screening: reduced myocardial blood flow reserve vs angiographic grading Limitations in implementing PET-based CAV assessments at various centers, and how transplant programs can use combined testing data For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 64: A look back at ISHLT2025
05/22/2025
Episode 64: A look back at ISHLT2025
On this special episode of JHLT: The Podcast, the Digital Media Editors take a look back at the exciting science that was on display at ISHLT2025, the ISHLT 45th Annual Meeting & Scientific Sessions. Topics include: Telomere biology disorders and lung transplantation The meeting's special focus on cardiogenic shock The apixiVAD trial exploring low dose apixaban in HeartMate 3 LVADs Myocardial recovery on durable LVADs For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . of the meeting can also be found at the JHLT website. Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 63: Severe PGD Using DCD Hearts
05/07/2025
Episode 63: Severe PGD Using DCD Hearts
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Peter Cho and senior author Abbas Ardehali, MD, to discuss the paper, “.” Peter is a third year medical student at Drexel University, and Dr. Ardehali is professor of surgery and medicine and the Director of the Heart, Lung, and Heart-Lung Transplant programs at UCLA. The episode explores: The study's findings regarding an increased incidence of severe PGD at 24 hours post-transplant in DCD over DBD recipients What risks weren't changed in DCD recipients—suggesting that DCD PGD is likely to be transient, and may have a different phenotype How NRP may impact the outcomes Mitigating the risk of PGD For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Tune in again later this month for the Digital Media Editors’ findings and observations from the ISHLT2025 Annual Meeting in Boston. Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 62: Apixaban Plasma Levels in Patients with HeartMate 3
04/10/2025
Episode 62: Apixaban Plasma Levels in Patients with HeartMate 3
Returning for a second study this month, the JHLT Digital Media Editors invite first author Charlotte Van Edom to discuss the paper, “.” As a cardiologist in training and a PhD candidate at the University Hospitals Leuven in Belgium, Van Edom’s work focuses on hemocompatibility and mechanical circulatory support, covering both short-term and long-term support. The episode explores: The evolution of the use and understanding of direct oral anticoagulants (DOACs) during LVAD support, including the increased focus on Factor Xa inhibitors Encouraging findings from the study and what clinical practices might need to change if introducing apixaban Additional studies exploring DOACs in LVAD patients For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Treat or research pulmonary vascular diseases? Check out the first April episode for a study on sotatercept in PAH patients. Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 61: Is Sotatercept safe in patients with PAH?
04/02/2025
Episode 61: Is Sotatercept safe in patients with PAH?
On this episode of JHLT: The Podcast, the Digital Media Editors invite author Ioana Preston, MD, to discuss the paper, “.” Dr. Preston is the director of the pulmonary hypertension center at Lahey Hospital and Medical Center in Burlington, Massachusetts, and has over 20 years of experience in caring for patients with PH, as well as multiple clinical trials in PH. The episode explores: What makes sotatercept unique as the first “biologic” in the treatment of PAH Hypotheses about the mechanism of action in sotatercept Sotatercept’s interaction with mPAP and what it indicates about the drug’s action on the pulmonary vasculature For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Those involved in the heart failure and mechanical circulatory support should tune in again later this month for a study on apixaban plasma levels in patients with HeartMate 3 support. Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 60: Riociguat in patients with PAH and Cardiometabolic Comorbidities
03/18/2025
Episode 60: Riociguat in patients with PAH and Cardiometabolic Comorbidities
Returning for a second study this month, the JHLT Digital Media Editors conduct an internal discussion on the paper, “.” The episode explores: The aging PAH population and the new comorbidities that must be considered in research How the study augments and expands on recent standards, like the 2022 ESC/ERS guidelines for pulmonary hypertension Limitations on the study and opportunities for future research For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Those on lung transplant teams should check the previous episode for a study on how rewarming ischemia time affects lung transplant outcomes. Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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Episode 59: Rewarming Ischemia Time in Lung Transplantation
03/05/2025
Episode 59: Rewarming Ischemia Time in Lung Transplantation
On this episode of JHLT: The Podcast, the Digital Media Editors invite lead author Jan Van Slambrouck, MD, to discuss the paper, “.” Dr. Van Slambrouck is a general surgeon who’s just finished his PhD training at the KU Leuven lab of respiratory disease and thoracic surgery in Belgium. The episode explores: How rewarming ischemia time (RIT) affects donor lungs, especially on the molecular level The pace of rewarming and how prior literature prepared the team to track and evaluate it Clinical strategies to reduce RIT and directly address molecular changes For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal membership at . Those involved in the pulmonary vascular disease space should tune in again later this month for a study on the safety and efficacy of riociguat in patients with PAH. Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at for a free subscription, or subscribe today at .
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