Episode 76: Evolocumab’s Impact on Coronary Physiology and Microstructure in De Novo Heart Transplant Recipients
Release Date: 01/21/2026
Episode 89: Improved Outcomes and Utilization in Hearts With 10° Static Cold Storage
JHLT: The Podcast
Today, JHLT: The Podcast discusses “,” a manuscript available online now and in the August print issue of JHLT. Today’s guest is senior author John Trahanas, MD, of the Vanderbilt University School of Medicine in Nashville, TN USA. In the episode, Dr. Trahanas and the editors discuss: What was learned from the lung 10°C trials and how the team adapted the devices for hearts The improved outcomes in PGD and survivability observed in the 10°C group How to determine if switching from ice to 10°C actually changed donor selection practices—and how it enabled the team to use more hearts ...
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Episode 88: Looking Back: Is Sotatercept Safe in Patients with PAH?
JHLT: The Podcast
In case you missed it, JHLT: The Podcast is re-releasing a past audience favorite for your listening pleasure. This month, we revisit a conversation regarding a study from the April 2025 issue of JHLT about the . This conversation with Ioana Preston, MD, of the Tufts University School of Medicine in Boston, explores: What makes sotatercept unique as the first “biologic” in the treatment of PAH Hypotheses about the mechanism of action in sotatercept Sotatercept’s interaction with mPAP and what it indicates about the drug’s action on the pulmonary vasculature For the latest studies...
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Episode 87: The Trifecta Heart Study: Assessing Donor Specific Antibodies in AMR
JHLT: The Podcast
JHLT: The Podcast returns for July with a paper entitled “,” available online now and in the July print issue of JHLT. Today’s guests are first author Katelynn S. Madill-Thomsen, PhD and senior author Philip F. Halloran, MD, PhD, both from the Alberta Transplant Applied Genomics Center in Canada. In the episode, the authors and editors discuss: Striking similarities—and key differences—in the DSA-negative and DSA-positive groups Changes to clinical practice based on the findings, including innovations from the kidney transplant community Future studies, including tools and therapies...
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Episode 86: A Patient Perspective on Ghost Coverage and Access to Immunosuppressants
JHLT: The Podcast
For the first time, JHLT: The Podcast welcomes a patient onto the podcast. The Digital Media Editors are pleased to welcome heart transplant recipient and patient advocate Payton Herres for a discussion about her in JHLT. In this compelling, moving discussion, Payton shares: Her treatment story—from her congenital diagnoses to her life-changing transplant—and her donor's story The difference between coverage and access—and how FDA labeling affected her access to an important component of her care What she wishes clinicians understood about long-term care of transplant patients For the...
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Episode 85: Assessing SCAI Shock Classification in Post-Cardiotomy Patients
JHLT: The Podcast
On JHLT: The Podcast, we kick off June with a paper entitled “,” which is available online now and in the June issue of JHLT. Today’s guests are first author Ufuk Baldan, MD and senior author Patrick Klein, MD, PhD, both of the Amsterdam University Medical Center in the Netherlands. We discuss: The heterogeneous nature of post-cardiotomy shock and challenges to treat Should serial assessments become standardized post-cardiac surgery? Does SCAI staging overestimate risk—and how do we interpret the stages we observe immediately post-op? What's next for this line of research? For the...
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Episode 84: What Was Hot at ISHLT2026
JHLT: The Podcast
On this special episode of JHLT: The Podcast, the Digital Media Editors take a look back at the exciting science that was on display at ISHLT2026, the ISHLT 46th Annual Meeting & Scientific Sessions. Topics include: Artificial intelligence and machine learning in transplantation, especially in assessing donor lungs and EVLP Cardiogenic Shock science at ISHLT2026, including a well-attended, all-new Academy The re-launch of the ISHLT International Thoracic Organ Transplant Registry, and the recent report in JHLT For the latest studies from JHLT, visit , or, if you’re an ISHLT member,...
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Episode 83: Consensus on Graft Dysfunction within 72 Hours After Heart Transplant
JHLT: The Podcast
JHLT: The Podcast starts May with an important ten-year update to a keystone document—the “.” The consensus summary—and a —appears in the May issue of JHLT, and is . The podcast is happy to host conference leader and first author Jon Kobashigawa, MD, Cedars-Sinai in Los Angeles, to talk about the consensus document, the conference, and PGD. The conversation includes discussion of: Why the document needed updating and how consensus was achieved The revised severity scale for PGD and the omission of the vasoactive-inotropic score Changes from the old document, including: Newer...
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Episode 82: JHLT Special Issue: Device Therapies
JHLT: The Podcast
In this episode, JHLT: The Podcast highlights a that’s just been released. The issue focuses on innovations in Device Therapies, and was edited by JHLT Deputy Editor Manreet Kanwar, MD, FACC, of the University of Chicago. Dr. Kanwar joins Digital Media Editor Van-Khue Ton, MD, PhD for a discussion about the special issue. The discussion explores: The importance of discussing device therapies in the advanced heart and lung failure communities The most anticipated device therapies in the pipeline for clinicians and patients to consider The impact of publishing in JHLT For the latest studies...
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Episode 81: Lung Cancer after Lung Transplant
JHLT: The Podcast
JHLT: The Podcast kicks off April with a discussion of the paper, “,” which appears in the April issue of JHLT. Senior author Pauline Pradère, MD, of Hôpital Marie Lannelongue in Paris, joins the episode to talk about the paper. The conversation includes discussion of: The overall survival of patients who develop lung cancer after lung transplant—and the key differences between the cohort of patients who developed cancer versus the patients who did not Managing lung cancer in transplant recipients Immunosuppression in these patients, and other potential changes to clinical practice...
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Episode 80: Solid Organ Transplantation and HIV Infection
JHLT: The Podcast
JHLT: The Podcast continues a themed month on HIV infection in solid organ transplant, building on our last episode’s exploration from Dr. Saeed at Montefiore in New York. Our guest this episode is infectious diseases expert Cameron Wolfe, MD, Professor of Medicine at Duke University Medical Center. He joined us while on sabbatical with his family in Brisbane Australia for a conversation about how transplant centers now consider HIV infection, including transplant recipients who are HIV positive. The discussion explores: How the HOPE Act of 2013 changed practice in the United States,...
info_outlineJHLT: The Podcast returns with an episode discussing the paper, “Impact of evolocumab on coronary physiology and microstructure in de-novo heart transplant recipients,” from the January issue of JHLT.
Featured on this episode is early career guest host Bin Yang, MD, of Massachusetts General Hospital. Mentored by Digital Media Editor Van-Khue Ton, MD, PhD, Dr. Yang shares hosting duties this episode and brings great questions to the discussion.
Drs. Yang and Ton are joined by the first author, Salma Karim, and senior author, Hans Eiskjaer, both from Aarhus University Hospital in Denmark.
The discussion explores:
- What imaging and physical markers the researchers used to determine if evolocumab was influencing the development of cardiac allograft vasculopathy (CAV)
- The potential role of lipid-lowering therapies or statins in treating CAV
- The relationship between CAV and microvascular resistance (IMR)
For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
In case you missed it, earlier this month the JHLT Digital Media Editors recapped their favorite papers from 2025. Take a listen!
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.