The Pain Beat (Episode 2) – Optogenetics and Chemogenetics for Pain Treatment: How Feasible Are They? How Effective Could They Be?
Release Date: 07/14/2020
The Pain Beat (Episode 18) –The Immune System and Pain
The Pain Beat
On this episode of The Pain Beat, Adam Dourson moderates a discussion about the role of the immune system in pain – what we know currently and ideas about how the immune system can be a target for new strategies to treat chronic pain. Podcast participants include: Geffroy Laumet, PhD, Michigan State University, US Luda Diachenko, PhD, McGill University, CA Thiago Cunha, PhD, University of Sao Paolo, BR Temugin Berta, PhD, University of Cincinnati, US Adam Dourson, PhD, Washington University in Saint Louis, US PRF thanks Lite Yang and Adam Dourson for producing the...
info_outline
The Pain Beat (Episode 17) – Experience, Study and Treatment of Visceral Pain
The Pain Beat
On this episode of The Pain Beat, Ewan St John Smith hosted fellow scientists and clinicians with expertise in visceral pain, including Federica La Russa - a scientist who also brought the patient perspective. The participants belong to the ADVANTAGE Consortium led by Geoff Woods, University of Cambridge, UK. The discussion covered psychological and clinical perspectives on the experience of visceral pain and treatment as well as the in latest preclinical research and how visceral pain studies differ from other types of pain. Podcast participants include: Ewan St. John...
info_outline
The Pain Beat (Episode 16) – A2CPS: Acute to Chronic Pain Signatures
The Pain Beat
This 16th episode of The Pain Beat highlights the work of a vibrant consortium of pain researchers working on a project known as Acute to Chronic Pain Signatures (A2CPS). A2CPS is focused on the identification of biomarkers to predict which patients will transition from acute to chronic pain, and which patients living with chronic pain can improve their quality of life with management (). The Pain Beat invited several Primary Investigators from A2CPS to talk about the work of the consortium, and how listeners of The Pain Beat can get involved themselves! Podcast participants include: ...
info_outline
The Pain Beat (Episode 15) – Nobel Prize: Somatosensation and Stories
The Pain Beat
This 15th episode of The Pain Beat is the third and final of a three-part series discussing the 2021 Nobel Prize in Physiology or Medicine – awarded to David Julius, University of California, San Francisco, USA and Ardem Patapoutian, Scripps Research, California, USA – for their work on molecules important for somatosensation (see PRF related interview , PRF related news story , part one of this series , and part two of this series ). In this episode, The Pain Beat spoke with a group of collaborators and former mentees to discuss what the discoveries mean for the somatosensory field, as...
info_outline
The Pain Beat (Episode 14) – Nobel Prize: A Conversation with Ardem Patapoutian and Bertrand Coste
The Pain Beat
This 14th episode of The Pain Beat is the second of a three-part series discussing the 2021 Nobel Prize in Physiology or Medicine – awarded to David Julius, University of California, San Francisco, USA and Ardem Patapoutian, Scripps Research, California, USA – for their work on molecules important for somatosensation (see PRF related interview , PRF related news story , and part one of this series ). In this episode, The Pain Beat spoke with Nobel Prize laureate Ardem Patapoutian and Bertrand Coste, Aix-Marseille University, France, to discuss their discovery of mechanically sensitive ion...
info_outline
The Pain Beat (Episode 13) – Nobel Prize: A Conversation with David Julius and Michael Caterina
The Pain Beat
This 13th episode of The Pain Beat is the first of a three-part series discussing the 2021 Nobel Prize in Physiology or Medicine – awarded to David Julius, University of California, San Francisco, USA and Ardem Patapoutian, Scripps Research, California, USA – for their work on molecules important for somatosensation (see PRF related interview , and PRF related news story ). In this episode, The Pain Beat spoke with Nobel Prize laureate David Julius and Michael Caterina, Johns Hopkins University School of Medicine, Maryland, USA, to discuss their discovery of TRPV1. The conversation...
info_outline
The Pain Beat (Episode 12) - A Tribute to Stephen McMahon
The Pain Beat
The twelfth episode of The Pain Beat is dedicated to Stephen McMahon, PhD, FMedSci (1954-2021). Stephen, affectionately known as “Mac,” was a world class pain researcher, lecturer, and inspiration to many. Our podcast guests pay homage to “Mac” with stories that illustrate his influence on the pain research field, and those in it. He will be remembered not only for his seminal contributions to our understanding of pain, but also for his generous and enthusiastic personal spirit which has left an indelible mark. Podcast participants include: David Bennett, MB, PhD, University of...
info_outline
The Pain Beat (Episode 11) - Evolution of Nociceptors
The Pain Beat
For its eleventh episode, The Pain Beat brought together experts to discuss the biological evolution of nociceptors, their subtypes, and plasticity as part of the Gulf Coast Consortium’s #Pain2021 Webinar Series. These experts study nociceptors across a variety of animal models, including Drosophila, C. elegans, cephalopods, rodents, and humans. The discussion focused on how an evolutionary perspective brings novel insights into the role and function of nociceptors and if, why, and how organisms experience pain. Podcast participants include: Greg Neely, PhD, University of Sydney, Australia...
info_outline
The Pain Beat (Episode 10) - Pain Research During the Pandemic and Beyond
The Pain Beat
For its tenth episode, The Pain Beat brought together guests from a variety of career stages to share their experiences conducting pain and pain-related research during the COVID-19 pandemic. Their discussion highlighted unique and shared experiences, how research priorities and strategies shifted in response to the pandemic, as well as ways in which colleagues found and offered support. Podcast participants include: Theanne Griffith, PhD, University of California, Davis, US Kelly Smith, PhD, University of Pittsburgh, US Kara Marshall, PhD, Baylor University, Texas, US Lindsay...
info_outline
The Pain Beat (Episode 9) – How is Pain Measured if it is Subjective?
The Pain Beat
For its ninth episode, The Pain Beat brought together experts in how pain is measured clinically and experimentally. This group discussed what is the difference between pain and nociception, why organisms experience pain and whether pain can be objectively measured since it is a subjective experience. Additionally, the group explored why researchers have relied on the measurement of nociception for so long and offer paths forward for the research community including a discussion of new technologies.
info_outlineEditor’s Note: Welcome to the second episode of The Pain Beat, PRF’s new monthly podcast series! Supported by a generous grant from The MAYDAY Fund, The Pain Beat brings together the world’s leading pain investigators in order to spark dialogue and debate around important ideas in pain research. Guided by Rebecca Seal, Scientific Director of The Pain Beat, these podcasts feature open and spirited discussion about the hottest topics in pain and how the field moves forward from here.
For the second episode, The Pain Beat gathered together a group of pain researchers in Keystone, Colorado, US, where two joint Keystone Symposia, Somatosensation: From Detection to Perception and Pain: Aligning the Target, were being held from February 2-5, 2020. The podcast participants include:
- Allan Basbaum, University of California San Francisco, US
- Robert Gereau, Washington University School of Medicine, US
- Yarimar Carrasquillo, National Institutes of Health, US
- Stephani Sutherland, PRF freelancer (moderator)
The group found a quiet spot amidst the hubbub of the meeting to discuss whether optogenetics and chemogenetics are feasible approaches to pain treatment, and if so, how effective they might be. The podcast also includes brief introductions to these two approaches.