The Pain Beat

The Pain Beat brings together the world’s leading pain investigators in order to spark dialogue and debate around important ideas in pain research.

The Pain Beat (Episode 16) – A2CPS: Acute to Chronic Pain Signatures 09/01/2023

The Pain Beat (Episode 16) – A2CPS: Acute to Chronic Pain Signatures This 16th episode of The Pain Beat highlights the work of a vibrant consortium of pain researchers working on a project known as Acute to Chronic Pain Signatures (A2CPS). A2CPS is focused on the identification of biomarkers to predict which patients will transition from acute to chronic pain, and which patients living with chronic pain can improve their quality of life with management (). The Pain Beat invited several Primary Investigators from A2CPS to talk about the work of the consortium, and how listeners of The Pain Beat can get involved themselves! Podcast participants include: Kathleen Sluka, PT, PhD, FAPTA, A2CPS Principal Investigator; University of Iowa, USA John Burns, PhD, A2CPS Principal Investigator; Rush University Medical Center, Illinois, USA Chad Brummett, MD, A2CPS Principal Investigator; University of Michigan, USA Michael Olivier, PhD, A2CPS Principal Investigator; Wake Forest University, North Carolina, USA. Stephani Sutherland, PhD, A2CPS Communications Director; Johns Hopkins University, Maryland, USA (moderator) /episode/index/show/thepainbeat/id/27913464

The Pain Beat (Episode 15) – Nobel Prize: Somatosensation and Stories 11/10/2022

The Pain Beat (Episode 15) – Nobel Prize: Somatosensation and Stories This 15th episode of The Pain Beat is the third and final of a three-part series discussing the 2021 Nobel Prize in Physiology or Medicine – awarded to David Julius, University of California, San Francisco, USA and Ardem Patapoutian, Scripps Research, California, USA – for their work on molecules important for somatosensation (see PRF related interview , PRF related news story , part one of this series , and part two of this series ). In this episode, The Pain Beat spoke with a group of collaborators and former mentees to discuss what the discoveries mean for the somatosensory field, as well as stories and insights about what it was like working with Drs. Julius and Patapoutian during that time. Podcast participants include: Allan Basbaum, PhD, FRS, University of California, San Francisco, USA Diana Bautista, PhD, University of California, Berkeley, USA Alexander Chesler, PhD, National Institutes of Health, Maryland, USA Ellen Lumpkin, PhD, University of California, Berkeley, USA Tayler Sheahan, PhD, University of Pittsburgh, USA (Host) /episode/index/show/thepainbeat/id/24968352

The Pain Beat (Episode 14) – Nobel Prize: A Conversation with Ardem Patapoutian and Bertrand Coste 09/14/2022

The Pain Beat (Episode 14) – Nobel Prize: A Conversation with Ardem Patapoutian and Bertrand Coste This 14th episode of The Pain Beat is the second of a three-part series discussing the 2021 Nobel Prize in Physiology or Medicine – awarded to David Julius, University of California, San Francisco, USA and Ardem Patapoutian, Scripps Research, California, USA – for their work on molecules important for somatosensation (see PRF related interview , PRF related news story , and part one of this series ). In this episode, The Pain Beat spoke with Nobel Prize laureate Ardem Patapoutian and Bertrand Coste, Aix-Marseille University, France, to discuss their discovery of mechanically sensitive ion channels – Piezo1 and Piezo2. Podcast participants include: Ardem Patapoutian, PhD, Scripps Research, California, USA Bertrand Coste, PhD, Aix-Marseille University, France Tayler Sheahan, PhD, University of Pittsburgh, USA (Host) /episode/index/show/thepainbeat/id/24373371

The Pain Beat (Episode 13) – Nobel Prize: A Conversation with David Julius and Michael Caterina 08/19/2022

The Pain Beat (Episode 13) – Nobel Prize: A Conversation with David Julius and Michael Caterina This 13th episode of The Pain Beat is the first of a three-part series discussing the 2021 Nobel Prize in Physiology or Medicine – awarded to David Julius, University of California, San Francisco, USA and Ardem Patapoutian, Scripps Research, California, USA – for their work on molecules important for somatosensation (see PRF related interview , and PRF related news story ). In this episode, The Pain Beat spoke with Nobel Prize laureate David Julius and Michael Caterina, Johns Hopkins University School of Medicine, Maryland, USA, to discuss their discovery of TRPV1. The conversation provides insight regarding their thought processes and problem solving, the enduring challenges of scientific discoveries, and the fun they had along the way. Podcast participants include: David Julius, PhD, University of California, San Francisco, USA Michael Caterina, MD, PhD, Johns Hopkins School of Medicine, Maryland, USA Tayler Sheahan, PhD, University of Pittsburgh, USA (Host) /episode/index/show/thepainbeat/id/24104877

The Pain Beat (Episode 12) - A Tribute to Stephen McMahon 05/27/2022

The Pain Beat (Episode 12) - A Tribute to Stephen McMahon The twelfth episode of The Pain Beat is dedicated to Stephen McMahon, PhD, FMedSci (1954-2021). Stephen, affectionately known as “Mac,” was a world class pain researcher, lecturer, and inspiration to many. Our podcast guests pay homage to “Mac” with stories that illustrate his influence on the pain research field, and those in it. He will be remembered not only for his seminal contributions to our understanding of pain, but also for his generous and enthusiastic personal spirit which has left an indelible mark. Podcast participants include: David Bennett, MB, PhD, University of Oxford, UK Gary Lewin, PhD, Max-Delbrück Center for Molecular Medicine, Berlin, Germany Irene Tracey, DPhil, University of Oxford, UK Franziska Denk, DPhil, King’s College London, UK (Host) /episode/index/show/thepainbeat/id/23246312

The Pain Beat (Episode 11) - Evolution of Nociceptors 04/14/2022

The Pain Beat (Episode 11) - Evolution of Nociceptors For its eleventh episode, The Pain Beat brought together experts to discuss the biological evolution of nociceptors, their subtypes, and plasticity as part of the Gulf Coast Consortium’s #Pain2021 Webinar Series. These experts study nociceptors across a variety of animal models, including Drosophila, C. elegans, cephalopods, rodents, and humans. The discussion focused on how an evolutionary perspective brings novel insights into the role and function of nociceptors and if, why, and how organisms experience pain. Podcast participants include: Greg Neely, PhD, University of Sydney, Australia Edgar T. Walters, PhD, University of Texas Health Science Center at Houston, USA Robyn Crook, PhD, San Francisco State University, California, USA Ewan St. John Smith, PhD, University of Cambridge, UK Ted Price, PhD, University of Texas at Dallas, USA (Moderator) Peter Grace, PhD, University of Texas MD Anderson Cancer Center, USA (Host) /episode/index/show/thepainbeat/id/22794275

The Pain Beat (Episode 10) - Pain Research During the Pandemic and Beyond 03/10/2022

The Pain Beat (Episode 10) - Pain Research During the Pandemic and Beyond For its tenth episode, The Pain Beat brought together guests from a variety of career stages to share their experiences conducting pain and pain-related research during the COVID-19 pandemic. Their discussion highlighted unique and shared experiences, how research priorities and strategies shifted in response to the pandemic, as well as ways in which colleagues found and offered support. Podcast participants include: Theanne Griffith, PhD, University of California, Davis, US Kelly Smith, PhD, University of Pittsburgh, US Kara Marshall, PhD, Baylor University, Texas, US Lindsay Ejoh, PhD Candidate, University of Pennsylvania, US Tayler Sheahan, PhD, University of Pittsburgh, US (Moderator) /episode/index/show/thepainbeat/id/22404626

The Pain Beat (Episode 9) – How is Pain Measured if it is Subjective? 12/07/2021

The Pain Beat (Episode 9) – How is Pain Measured if it is Subjective? For its ninth episode, The Pain Beat brought together experts in how pain is measured clinically and experimentally. This group discussed what is the difference between pain and nociception, why organisms experience pain and whether pain can be objectively measured since it is a subjective experience. Additionally, the group explored why researchers have relied on the measurement of nociception for so long and offer paths forward for the research community including a discussion of new technologies. /episode/index/show/thepainbeat/id/21406034

The Pain Beat (Episode 8) – Studying and Understanding Sex Differences in Pain: The How and the Why 12/07/2021

The Pain Beat (Episode 8) – Studying and Understanding Sex Differences in Pain: The How and the Why For its eighth episode, The Pain Beat gathered together a group of pain researchers with expertise in the study of sex differences in pain. The group discussed their own discoveries of sex differences in pain in the course of their research, why pain investigators should pay attention to sex differences and how they should go about examining them, and much more. /episode/index/show/thepainbeat/id/21405944

The Pain Beat (Episode 7) – Brain Imaging of Pain in People: What Have We Learned? Where Are We Going? 05/26/2021

The Pain Beat (Episode 7) – Brain Imaging of Pain in People: What Have We Learned? Where Are We Going? This Pain Beat podcast discusses pain neuroimaging studies in people, with a focus on how studies of expectation and the placebo effect have advanced our understanding in this area. Podcast participants include: /episode/index/show/thepainbeat/id/19249037

The Pain Beat (Episode 6) - Communicating Science in an Empathic and Inclusive Way: Why – and How – Should Pain Researchers Do It? 02/21/2021

The Pain Beat (Episode 6) - Communicating Science in an Empathic and Inclusive Way: Why – and How – Should Pain Researchers Do It? For the sixth episode, The Pain Beat gathered together an international group of pain researchers, science communicators and civic science advocates to discuss what effective, empathic and inclusive science communication looks like. /episode/index/show/thepainbeat/id/18028751

The Pain Beat (Episode 5) – The Coding of Sensory Information: Population Coding or Labeled Lines? 01/11/2021

The Pain Beat (Episode 5) – The Coding of Sensory Information: Population Coding or Labeled Lines? In the fifth episode of The Pain Beat, researchers discuss how the mammalian nervous system encodes sensory modalities related to touch, pain and temperature. Are there labeled lines? Is there population coding? Do the mechanisms differ by location – the brain, spinal cord or periphery? /episode/index/show/thepainbeat/id/17506226

The Pain Beat (Episode 4) – The Use of Human Tissue in Pain Research: Where Are We Now, and Where Are We Going? 10/25/2020

The Pain Beat (Episode 4) – The Use of Human Tissue in Pain Research: Where Are We Now, and Where Are We Going? The Pain Beat gathered together a group of pain researchers via Zoom to discuss the use of human tissue in pain research and prospects for clinical translation of new knowledge emerging from this approach. /episode/index/show/thepainbeat/id/16536212

The Pain Beat (Episode 3) – The Transition from Acute to Chronic Pain 09/17/2020

The Pain Beat (Episode 3) – The Transition from Acute to Chronic Pain A group of pain researchers gather to discuss ideas and issues related to the transition from acute to chronic pain. /episode/index/show/thepainbeat/id/16051394

The Pain Beat (Episode 2) – Optogenetics and Chemogenetics for Pain Treatment: How Feasible Are They? How Effective Could They Be? 07/14/2020

The Pain Beat (Episode 2) – Optogenetics and Chemogenetics for Pain Treatment: How Feasible Are They? How Effective Could They Be? In the second episode of The Pain Beat, leading pain researchers discuss whether optogenetics and chemogenetics are feasible approaches to pain treatment, and if so, how effective they might be. /episode/index/show/thepainbeat/id/15206540

The Pain Beat (Episode 1) – Pain Targets: Molecules? Cells? Circuits? Systems? 06/14/2020

The Pain Beat (Episode 1) – Pain Targets: Molecules? Cells? Circuits? Systems? This podcast discusses the following question: What Biological Levels Should Be Targeted to Produce the Most Effective Pain Therapies: Molecules? Cells? Circuits? Or Systems? Hosted by the IASP Pain Research Forum (https://www.painresearchforum.org). /episode/index/show/thepainbeat/id/14814206

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