110: Evaluating Aquablation Therapy to Treat Prostate Cancer – WATER IV Prostate Cancer Trial – Inderbir S. Gill, MD
Release Date: 12/23/2025
111: TULSA-PRO, the only AI-powered, MRI-guided Treatment for Men with Prostate Cancer – Y. Mark Hong, MD
The Prostate Health Podcast
(or find the link on our ) Join our Follow Dr. Pohlman on and Sign up for the You can access Dr. Pohlman’s free mini-webinar, where he discusses his top three tips to promote men’s prostate health, longevity, and quality of life . Podcast Partner: TULSA-PRO:
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110: Evaluating Aquablation Therapy to Treat Prostate Cancer – WATER IV Prostate Cancer Trial – Inderbir S. Gill, MD
The Prostate Health Podcast
There is now a significant opportunity to improve the safety and quality of life outcomes for men requiring treatment for prostate cancer. Today, we’re discussing the Water IV Prostate Cancer trial, an innovative and meaningful clinical trial that is actively enrolling patients to assess how the safety and efficacy of Aquablation therapy compares with radical prostatectomy in men with localized prostate cancer. I’m excited to share my experience as a current investigator for that study and to have Dr. Inderbir Gill, the co-principal investigator from the University of Southern...
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109: Using Electrical Pulses (The NanoKnife System) to Treat Prostate Tumors – L. Spencer Krane, MD
The Prostate Health Podcast
There is a new treatment option available now that can precisely target prostate lesions with electrical pulses, while helping preserve sexual function and urinary control. Whether you or a loved one has prostate disease, or you are a urologist considering this technology for your practice, you will not want to miss today’s discussion on this innovative new option. September is Prostate Cancer Awareness Month, so we have a special episode today to kick it off. We are excited to welcome the distinguished urologist, Dr. Spencer Krane, to the Prostate Health Podcast. Dr. Krane is the Chief...
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108: How a Prostate Health Coach Can Be an Essential Component to Your Journey with an Enlarged Prostate (BPH)
The Prostate Health Podcast
Today, our guest is Tom, a 67-year-old retired senior executive who found it challenging to get an accurate diagnosis and find effective treatment for his enlarged prostate. Frustrated by his limited options and with a growing sense of mistrust, he consulted with several providers before realizing he needed the guidance of a prostate health coach. Tom retired as a senior IT executive with over 40 years of experience leading transformative technology strategies to drive business growth for global organizations. He led global IT initiatives for Fortune 500 companies across various...
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107: The Expanding Role for Modern Low Dose Rate (LDR) Prostate Brachytherapy – Steven Kurtzman, MD and Ankit Agarwal, MD
The Prostate Health Podcast
We are delighted to partner with Western Radiation Oncology today, with two of their distinguished radiation oncologists joining us on the Prostate Health Podcast. LDR (Low Dose Rate) prostate brachytherapy has recently been an underutilized treatment for prostate cancer. However, advancements in modern techniques have demonstrated that LDR brachytherapy, a procedure that can be performed quite easily in an ambulatory surgery center, offers high cure rates with minimal long-term complications, making it a convenient, non-invasive option for men with prostate cancer. Today, we chat...
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106: The Elevated PSA Pathway and My Initial Experience with the EpiSwitch PSE Test - Garrett D. Pohlman, MD
The Prostate Health Podcast
Prostate cancer screening is an essential aspect of men’s health, and current advancements in testing are making early detection more precise than ever before. While the PSA (Prostate-Specific Antigen) test has long been the standard, it has limitations and may lead to unnecessary biopsies. The new EpiSwitch PSE test helps differentiate between high and low prostate cancer risks. With an impressive 94% accuracy rate, the EpiSwitch PSE test empowers patients and physicians to make informed decisions. In this episode, Dr. Garrett Pohlman explores the latest innovations in prostate cancer...
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105: How Optilume® BPH Allowed a Urologist to Help His Best Friend - Sijo Parekattil, MD, FACS
The Prostate Health Podcast
We are thrilled to partner with Laborie to bring you this episode of the Prostate Health Podcast. In Episode 91, we introduced the Optilume® procedure, a cutting-edge new solution for an enlarged prostate, or BPH, that requires no heating, cutting, or permanent implantation. Today, we bring you the story of how Dr. Sijo Parekattil, a leading urologist specializing in cutting-edge treatments for men with BPH, was approached by Vinit, his closest friend, who was struggling with the effects of an enlarged prostate. Dr. Sijo Parekattil is the Director of Avant Concierge Urology in...
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104: Improving Prostate Cancer Detection with Innovative OnQ Prostate MRI Software - Brittany Hunt
The Prostate Health Podcast
We are delighted to partner with Cortechs.ai to bring you this episode of the Prostate Health Podcast. Prostate MRI has become a valuable tool in enhancing the detection, localization, and staging of prostate cancer. However, current protocols come with various challenges, like inconsistent accuracy, a significant rate of missed clinically significant prostate cancers, and considerable variability in how different radiologists interpret the results. We are thrilled to have Brittany Hunt, the head of Prostate Business Development at Cortechs.ai, joining us on the show today to introduce...
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103: Using a Robotic Procedure to Remove Prostate Tissue with the Power of Water - Jennifer E. Lloyd-Harris, MD
The Prostate Health Podcast
We are delighted to partner with Procept BioRobotics to bring you this episode of the Prostate Health Podcast. The primary reason men consult urologists is due to an enlarged prostate. With June being Men's Health Month, we are thrilled to welcome urologist Dr. Jennifer Lloyd-Harris on the podcast today to discuss Benign Prostatic Hyperplasia (BPH). BPH is a significant health issue for men, and we are excited to inform listeners about a groundbreaking water-based technology to bring men relief from their symptoms. We also have Ken, a patient of Dr. Lloyd-Harris, joining us to...
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102: Penile Rehab: Erectile Dysfunction after Prostatectomy – Helen L. Bernie, DO, MPH
The Prostate Health Podcast
Men have many challenges to deal with when battling prostate cancer, including managing the side effects of their treatment. One common issue men face after a radical prostatectomy is erectile dysfunction. As June is Men's Health Month, we are fortunate to have men's health expert Dr. Helen Bernie joining us today to provide a modern perspective on restoring erectile function post-prostatectomy through penile rehabilitation. Dr. Bernie is a board-certified and fellowship-trained urologist. She is the Director of Sexual and Reproductive Medicine, the Andrology Fellowship Program...
info_outlineThere is now a significant opportunity to improve the safety and quality of life outcomes for men requiring treatment for prostate cancer.
Today, we’re discussing the Water IV Prostate Cancer trial, an innovative and meaningful clinical trial that is actively enrolling patients to assess how the safety and efficacy of Aquablation therapy compares with radical prostatectomy in men with localized prostate cancer. I’m excited to share my experience as a current investigator for that study and to have Dr. Inderbir Gill, the co-principal investigator from the University of Southern California, join us.
Dr. Gill is the current Chairman and Distinguished Professor of Urology of the University of Southern California Department of Urology. He is also the Founding Executive Director of the USC Institute of Urology.
Stay tuned to learn who qualifies as a candidate to participate in the trial, how the study works, and how you can get involved.
Disclaimer: The Prostate Health Podcast is for informational purposes only. Nothing in this podcast should be construed as medical advice. By listening to the podcast, no physician-patient relationship has been formed. For more information and counseling, you must contact your personal physician or urologist with questions about your unique situation.
Pertinent disclosure for today’s episode – Today’s episode is sponsored by PROCEPT BioRobotics Corporation, which manufactures and sells the Aquablation system. Dr. Pohlman is also a paid advisor for PROCEPT BioRobotics Corporation.
Show Highlights:
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How the Water IV Prostate Cancer trial compares Aquablation directly with radical prostatectomy
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How the Water IV Prostate Cancer trial is the first prospective, randomized U.S. trial comparing a novel prostate cancer treatment to radical prostatectomy.
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Who qualifies as an eligible participant for the Water IV Prostate Cancer trial?
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The requirements for those participating in the Water IV Prostate Cancer trial
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How the trial randomizes the participants in the trial
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What the study measures as its primary and secondary endpoints
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How recruitment for the trial has exceeded all expectations
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When the early trial results should come out
Links:
WATER IV Prostate Cancer Study webpage: water4pca.com
Contact the study team: wateriv@procept-biorobotics.com
Aquablation Therapy website: https://aquablation.com/
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Sign up for the Prostate Health Academy
You can access Dr. Pohlman’s free mini-webinar, where he discusses his top three tips to promote men’s prostate health, longevity, and quality of life here.