Episode 210: Hashimoto’s Revisited - A Conversation with Dr. Izabella Wentz
Release Date: 11/11/2025
Thyroid Answers Podcast
Is Your Brain Keeping You Stuck in Thyroid Purgatory? | Thyroid Shorts #22 Most people assume persistent hypothyroid symptoms mean their thyroid is failing or their medication is wrong. But what if your thyroid isn’t broken at all, and your brain’s perception of safety or threat is controlling everything? In this episode, Dr. Eric Balcavage reveals why many people get trapped in Thyroid Purgatory. In this state, thyroid physiology is perfectly adapted to protection, not performance, which is why more T4 or adding T3 often makes symptoms worse, not better. You’ll learn how two...
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Many people start T3 medication hoping for more energy and mental clarity—only to end up feeling wired, anxious, or unable to sleep. In this episode of Thyroid Shorts, Dr. Eric Balcavage explains why too much or too little T3 can both amplify anxiety and insomnia, and how to restore calm by shifting from defense mode to recovery mode. You’ll learn how the brain’s fear center (the amygdala) interprets stress, how local T3 activity inside the brain differs from global thyroid output, and why “state before hormone” is the key to lasting recovery. Featuring insights from two pivotal...
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Rewiring the Brain for Thyroid Recovery with Dr. Patrick Porter What if you could train your brain to help your thyroid recover? In this episode, Dr. Eric Balcavage sits down with Dr. Patrick Porter, creator of BrainTap®, to explore how brainwave training, stress regulation, and nervous-system balance can unlock your body’s natural healing potential. In this conversation: How chronic stress keeps the brain stuck in “danger mode” and blocks thyroid recovery Why the amygdala, HPA axis, and thyroid are part of one continuous feedback loop The role of neuroplasticity and...
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Every winter, TSH rises—but that doesn’t mean thyroid failure. Dr Eric Balcavage explains how photoperiod, melatonin, and circannual rhythms alter TRH → TSH → T3 and why seasonal adaptation is often misdiagnosed as hypothyroidism. In this episode, you’ll learn: ✅ How shorter days and colder temperatures reset the hypothalamic–pituitary–thyroid axis ✅ Why macro-TSH raises lab TSH without true hypothyroidism ✅ How both conventional and functional models misread winter physiology ✅ Five ways to align with your seasonal thyroid rhythm (light, rest, minerals, movement,...
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Stress and Holiday Hypothyroidism | How Stress Lowers T3 and Raises rT3 | Dr. Eric Balcavage – Thyroid Shorts Ep. 19 The holidays are supposed to be joyful — but for many with hypothyroidism or Hashimoto’s, they trigger fatigue, weight gain, brain fog, and anxiety. In this episode, Dr. Eric Balcavage, creator of the Adaptive Thyroid Model™, explains how stress physiology, poor sleep, and inflammation can turn down your thyroid hormone activity — even when your blood tests look “normal.” Learn why holiday stress, late nights, sugar spikes, alcohol, and over-training push your...
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Most people are told: “If you have thyroid antibodies, you have Hashimoto’s. If you don’t, you don’t.” In this episode, Dr. Eric Balcavage, creator of the Adaptive Thyroid Model™, revisits that idea and shows why antibodies are only one piece of a much bigger picture. Discover how: ✅ Th1 and Th17 T-cells, CD8 T-cells, and low T-regs drive thyroid inflammation and tissue damage ✅ PAMPs (pathogen signals) and DAMPs (cell-danger signals) can bind to pattern-recognition receptors [PRRs] on thyroid cells, triggering cytokines and interferon activity ✅ Antibodies may confirm...
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In this episode of Thyroid Answers, Dr. Eric Balcavage sits down with pharmacist and bestselling author Dr. Izabella Wentz to revisit one of the most misunderstood conditions in modern medicine — Hashimoto’s thyroiditis. They explore how new research and clinical experience are reshaping what we know about autoimmune thyroid disease, why so many women still struggle with fatigue, weight gain, and brain fog despite “normal” thyroid labs, and what it really takes to recover thyroid function from the inside out. Dr. Wentz and Dr. Balcavage break down the differences between managing...
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Are you struggling with hypothyroid symptoms like fatigue, weight gain, hair loss, or brain fog? Have you been told the reason is that you have “low T3”? Many patients are told the solution is simple: add T3 thyroid hormone replacement. But is that the truth? Is that the correct strategy? In this Thyroid Answers Shorts episode, Dr. Eric Balcavage, functional medicine thyroid expert and host of the Thyroid Answers Podcast, explains: ✅ Why low T3 doesn’t always mean you need medication ✅ How stress, inflammation, and the Cell Danger Response affect T4-to-T3 conversion ✅ Why...
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Are you ready to challenge the myths of aging and discover how to stay strong, vital, and resilient for decades to come? In this episode of the Thyroid Answers Podcast, Dr. Eric Balcavage sits down with Dr. Mani Kukreja to explore the cutting-edge science of healthy aging. We dive into: Why aging is not just about years—but about cellular health and resilience The hidden role of thyroid physiology in longevity and vitality Nutrition, movement, and lifestyle strategies that slow the aging clock The difference between simply “managing” disease and truly recovering health Practical steps...
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Your thyroid doesn’t work in isolation. It relies on your liver, your bile, and even your gut bacteria to keep hormone conversion running smoothly. In this episode of Thyroid Shorts, Dr. Eric Balcavage explains how thyroid hormone T3 regulates bile acid production, shapes your microbiome, and keeps your gut lining strong in a state of homeostasis. But what happens when stress, inflammation, or the Cell Danger Response lower circulating T3? The liver shifts bile chemistry, gut bugs change, and your barrier can loosen. This isn’t necessarily dysfunction — it’s your body’s intelligent...
info_outlineIn this episode of Thyroid Answers, Dr. Eric Balcavage sits down with pharmacist and bestselling author Dr. Izabella Wentz to revisit one of the most misunderstood conditions in modern medicine — Hashimoto’s thyroiditis.
They explore how new research and clinical experience are reshaping what we know about autoimmune thyroid disease, why so many women still struggle with fatigue, weight gain, and brain fog despite “normal” thyroid labs, and what it really takes to recover thyroid function from the inside out.
Dr. Wentz and Dr. Balcavage break down the differences between managing Hashimoto’s with medication and restoring thyroid health through the Adaptive Thyroid Model™, focusing on root causes suc as gut health, inflammation, hormone balance, and stress physiology.
Key Topics:
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What most doctors miss about Hashimoto’s and autoimmune thyroiditis
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The connection between stress, sleep, gut health, and thyroid autoimmunity
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Why “normal labs” can hide ongoing thyroid dysfunction
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How estrogen, cortisol, and inflammation alter thyroid hormone conversion
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The role of diet, supplements, and lifestyle in reversing Hashimoto’s patterns
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How to know if your low T3 is adaptive — not failure
- And more ...
Dr. Izabella Wentz is a compassionate, innovative, solution-focused integrative pharmacist dedicated to finding the root causes of chronic health conditions. Her passion stems from her own diagnosis with Hashimoto’s thyroiditis in 2009, following a decade of debilitating symptoms.
As an accomplished author, Dr. Wentz has written several best-selling books, including the New York Times best seller Hashimoto’s Thyroiditis: Lifestyle Interventions for Finding and Treating the Root Cause, the protocol-based #1 New York Times best seller Hashimoto’s Protocol: A 90-Day Plan for Reversing Thyroid Symptoms and Getting Your Life Back, and the Wall Street Journal best seller Hashimoto’s Food Pharmacology: Nutrition Protocols and Healing Recipes to Take Charge of Your Thyroid Health.
Her latest book, Adrenal Transformation Protocol, was released on April 18th, 2023. The book focuses on resetting the body’s stress response through targeted safety signals and features a 4-week program that has already helped over 3,500 individuals. The program has an impressive success rate, with over 80% of participants improving their brain fog, fatigue, anxiety, irritability, sleep issues, and libido.
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