TWiN 35: Neuromodulation in treatment-resistant depression
Release Date: 12/06/2022
This Week in Neuroscience
TWiN explores how theta phase shifts mediate contextual perception of facial expressions during everyday social interactions. Hosts: , Vivianne Morrison, and Tim Cheung Subscribe (free): , , Links for this episode Neural computations underlying (Cell Rep) Previous experience (Front Human Neurosci) Timestamps by . Thanks! Music is by Send your neuroscience questions and comments to twin@microbe.tv
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TWiN reviews the underlying neurobiological mechanisms of overeating and obesity, the role of the hypothalamus and reward systems in controlling food intake and energy balance, and how dysregulation in these systems leads to overeating. Hosts: , Vivianne Morrison, and Tim Cheung Subscribe (free): , , Links for this episode Neurobiology of (Neuron) Timestamps by . Thanks! Music is by Send your neuroscience questions and comments to twin@microbe.tv
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TWiN explains epidemiological data showing that exposure to air pollution was associated with an increased risk of developing Lewy body dementia, and nasal administration of air pollution in mice led to brain atrophy and impaired cognition and motor function. Hosts: , Vivianne Morrison, and Tim Cheung Subscribe (free): , , Links for this episode Links between (Science) Letter from Susan Schneider Williams (Lewy Body Dementia UK) (Wikipedia) Timestamps by . Thanks! Music is by Send your neuroscience questions and comments to...
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TWiN explains how visual neurons show functional flexibility by selectively responding to subsets of inputs representing attended objects while ignoring those conveying information about irrelevant objects. Hosts: , Vivianne Morrison, and Tim Cheung Subscribe (free): , , Links for this episode Gamma-band synchronization in (Nat Comm) Timestamps by . Thanks! Music is by Send your neuroscience questions and comments to twin@microbe.tv
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TWiN discusses research showing that Lactobacillus acidophilus promotes cognitive function recovery after cerebral ischemia, by regulating microglial peroxisomal function. Hosts: , Vivianne Morrison, and Tim Cheung Subscribe (free): , , Links for this episode Arc is pdb (PDB) Probiotics (Cell Host Microbe) Timestamps by . Thanks! Music is by Send your neuroscience questions and comments to twin@microbe.tv
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TWiN explains research which identifies the regions of the brain that register a long-lasting aversion to potentially poisonous food even with meal to illness delays of several days. Hosts: , and Tim Cheung Subscribe (free): , , Links for this episode A neural mechanism for (Nature) Timestamps by . Thanks! Music is by Send your neuroscience questions and comments to twin@microbe.tv
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TWiN reveals that proteins travel from the blood to the brain where they are taken up by microglia, revealing a new mode of communication between the brain and the periphery. Hosts: , Tim Cheung, and Vivianne Morrison Subscribe (free): , , Links for this episode Circulatory proteins taken up by (bioRxiv) Timestamps by . Thanks! Music is by Send your neuroscience questions and comments to twin@microbe.tv
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TWiN discusses experiments which show that high-fidelity memories that lose their precision with time depends on reorganization of hippocampal circuitry. Hosts: , , and Tim Cheung Subscribe (free): , , Links for this episode and the hippocampus (Nature) Changes in hippocampi of (PNAS) Timestamps by . Thanks! Music is by Send your neuroscience questions and comments to twin@microbe.tv
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Tim explains AI co-scientist, a tool released by Google, which it hopes to help scientists generate hypotheses and research proposals, and to accelerate the speed of scientific and biomedical discoveries. Hosts: , Tim Cheung, and Vivianne Morrison Subscribe (free): , , Links for this episode AI cracks (BBC) scientific breakthroughs (Google Research) Towards an (arXiv) Timestamps by . Thanks! Music is by Send your neuroscience questions and comments to twin@microbe.tv
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TWiN explains a study showing that when a mouse is confronted with an unconscious conspecific, it engages in behavior including tongue-dragging to resuscitate the animal via a tongue-brain connection. Hosts: , Tim Cheung, and Vivianne Morrison Subscribe (free): , , Links for this episode in mice (Sci Adv) Timestamps by . Thanks! Music is by Send your neuroscience questions and comments to twin@microbe.tv
info_outlineJason and Tim review the use of an implanted chronic deep brain sensing and stimulation device to carry out biomarker-driven closed-loop therapy that resulted in a rapid and sustained improvement in depression.
Hosts: Jason Shepherd and Timothy Cheung
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Links for this episode
- Closed-loop neuromodulation for depression (Nat Med)
- Timestamps by Jolene. Thanks!
Music is by Ronald Jenkees
Send your neuroscience questions and comments to twin@microbe.tv