TWiV 1273: Myocarditis and mimicry
This Week in Virology
TWiV explains studies which reveal that Inhibition of CXCL10 and IFN-γ mitgates myocarditis associated with SARS-CoV-2 mRNA vaccination, and identification of a bacteriophage T7 protein that antagonizes the DNA restriction system of the host by mimicking B form DNA. Hosts: and Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV Understanding mRNA (Sci Transl Med) T7 protein overcomes (J Mol Biol) Structure of T7 protein that (Mol Cell) on TWiV 1283 Timestamps by Ramsey. Thanks! ...
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TWiV 1282: Clinical update with Dr. Daniel Griffin
This Week in Virology
Calling out “Happy Christmas to all and to all a good-night, Dr. Griffin and Vincent Racaniello discuss high path influenza in dairy herds in Wisconsin and Marburg virus in Ethiopia before Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the slightly higher association of COVID-19 infection with death than following influenza infection, benefit of passive infant immunization with niresevimab, association of COVID-19 vaccine immunogenicity protection...
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TWiV 1281: Sex, herpes, and plankton
This Week in Virology
Vincent travels to Tegernsee, Germany for the Sixth Ringberg Symposium on Giant Viruses, where he talks with John Archibald, Susana Coelho, and Tom Delmont about their work on – you guessed it – giant viruses. Host: Guests: , , and Subscribe (free): , , Become a of TWiV! Links for this episode Transposable elements shaping (Genome Biol) link herpesviruses to giant viruses (Nature) Mirusviruses predicted to (Nat Micro) in the marine protist Aurantiochytrium (Nat Com) Timestamps by Ramsey....
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TWiV 1280: Clinical update with Dr. Daniel Griffin
This Week in Virology
In his weekly clinical update, Dr. Griffin and Vincent Racaniello protest Vinjay Prasad, head of CBER FDA Nov memo stating administration of the COVID-19 vaccine resulted in 10 children’s deaths, but are cautiously delighted by the December memo from those in CBER who dispute this data-less claim, how in 31 states pertussis vaccination rates have declined before Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, of clinical outcomes of oseltamivir versus baloxavir...
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TWiV 1279: Let hepatitis b
This Week in Virology
TWiV reviews considerations and perspectives on phage therapy, and the Nobel Prize-winning discovery of hepatitis b virus. Hosts: , , , and Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV Immune 100 WHO global expert committee: (News-Medical) Considerations on (Nat Comm) What is ? (CDC) History of phage therapy (, ) JAMA Viruses that (can) make you well () The InVinceable TWiV () Blumberg Particles associated with (Nature) HBV vaccination...
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TWiV 1278: Clinical update with Dr. Daniel Griffin
This Week in Virology
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the rise in norovirus infections, contamination of infant formula and botulism outbreak, confusion and response to the CDC’s ACIP decision to reverse the recommendation for a birth dose of the hepatis B virus vaccine and how states in the Northwest and Northeast are responding as well as some insurance companies, then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, South Carolina’s imposed quarantine of...
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TWiV 1277: Vaccine talk with Jake Scott
This Week in Virology
Infectious diseases physician Jake Scott returns to TWiV to discuss the dangerous anti-vaccine policies being established in the US and what RFK Jr. and his associates get wrong. Hosts: , , and Angela Mingarelli Guest: Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV Vaccine RCT (CIDRAP) What RFK Jr gets (Conversation) RFK Jr’s case (STAT) Too many kids’ vaccines? (STAT) Timestamps by Ramsey. Thanks! Weekly Picks Angela – Angela Palmer, science meets art...
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TWiV 1276: Clinical update with Dr. Daniel Griffin
This Week in Virology
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the positive side effect of the shingles vaccine on dementia outcomes and how one dose of the HPV vaccine is non-inferior to two doses, but are dismayed about the FDA’s secrecy around the inflammatory statement that the COVID-19 vaccine is linked to the death of 10 children. Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, effectiveness of maternal administration of the RVS vaccine or the...
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TWiV 1275: An amazing sequence and a gutsy therapy
This Week in Virology
TWiV explains the Nobel Prize-winning discovery of pre-mRNA splicing, and engineering bacteriophage to deliver proteins to the human intestine. Hosts: , , and Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV Immune 100 of adenovirus mRNA (PNAS) An in adenovirus mRNA (Cell) Nobel Prize for (Nobel) A in adenovirus late mRNAs (Cell) with Phillip A. Sharp (ASM) Protein production in the gut by (Nat Biotech) phage T4 (Curr Op Virol) Timestamps by Ramsey....
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TWiV 1274: Clinical update with Dr. Daniel Griffin
This Week in Virology
In his weekly clinical update, Dr. Griffin and Vincent Racaniello wish everyone a Happy Thanksgiving and then decry appointment of the Louisiana State surgeon general as deputy chief of the CDC, the 3 children’s deaths during this fall’s pertussis outbreak, the Marburg virus outbreak in Ethiopia, results of the phase 1 safety trial for the novel poliovirus vaccines nOPV1 and nOPV3, and the first human death from H5N5 influenza virus infection in the US this fall, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the...
info_outlineTWiV reviews liver damage caused by over use of vitamin A in Texas, vitamin A does not change clinical course of measles in high income country, NIH cuts COVID-19 research, US ends vaccine funds for poor countries, anti-vaxxer hired to study vaccines and autism, new DURC policy, Jamaican fruit bat competence for filoviruses, and human outbreaks of Oropouche virus reassortant in Brazil.
Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker
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Links for this episode
- Support science education at MicrobeTV
- ASV 2025
- Vitamin A liver disease in Texas (NY Times)
- Vitamin A doesn’t help measles in high-income countries (Pediat Inf Dis)
- NIH cancels COVID grants (Science)
- US ends vaccine funds for poor countries (NY Times)
- Anti-vaxxer to study vaccines and autism (Sci Based Med)
- DURC rules revised (USG and NIH guidance)
- Filoviruses and Jamaican fruit bats (Nat Comm)
- Oropouche outbreaks in Brazil (Nat Med)
- Woolly mice (NPR)
- Letters read on TWiV 1205
- Timestamps by Jolene Ramsey. Thanks!
Weekly Picks
Brianne – Math of March Madness Brackets
Kathy – Wood frogsicles #1 and #2
Alan – Rare glimpse of baby polar bears emerging from dens
Vincent – Hikaru Utada Would Rather Play CERN Than Coachella
Intro music is by Ronald Jenkees
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Content in this podcast should not be construed as medical advice.