TWiV 1273: Myocarditis and mimicry
This Week in Virology
TWiV explains studies which reveal that Inhibition of CXCL10 and IFN-γ mitgates myocarditis associated with SARS-CoV-2 mRNA vaccination, and identification of a bacteriophage T7 protein that antagonizes the DNA restriction system of the host by mimicking B form DNA. Hosts: and Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV Understanding mRNA (Sci Transl Med) T7 protein overcomes (J Mol Biol) Structure of T7 protein that (Mol Cell) on TWiV 1283 Timestamps by Ramsey. Thanks! ...
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TWiV 1282: Clinical update with Dr. Daniel Griffin
This Week in Virology
Calling out “Happy Christmas to all and to all a good-night, Dr. Griffin and Vincent Racaniello discuss high path influenza in dairy herds in Wisconsin and Marburg virus in Ethiopia before Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the slightly higher association of COVID-19 infection with death than following influenza infection, benefit of passive infant immunization with niresevimab, association of COVID-19 vaccine immunogenicity protection...
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TWiV 1281: Sex, herpes, and plankton
This Week in Virology
Vincent travels to Tegernsee, Germany for the Sixth Ringberg Symposium on Giant Viruses, where he talks with John Archibald, Susana Coelho, and Tom Delmont about their work on – you guessed it – giant viruses. Host: Guests: , , and Subscribe (free): , , Become a of TWiV! Links for this episode Transposable elements shaping (Genome Biol) link herpesviruses to giant viruses (Nature) Mirusviruses predicted to (Nat Micro) in the marine protist Aurantiochytrium (Nat Com) Timestamps by Ramsey....
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TWiV 1280: Clinical update with Dr. Daniel Griffin
This Week in Virology
In his weekly clinical update, Dr. Griffin and Vincent Racaniello protest Vinjay Prasad, head of CBER FDA Nov memo stating administration of the COVID-19 vaccine resulted in 10 children’s deaths, but are cautiously delighted by the December memo from those in CBER who dispute this data-less claim, how in 31 states pertussis vaccination rates have declined before Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, of clinical outcomes of oseltamivir versus baloxavir...
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TWiV 1279: Let hepatitis b
This Week in Virology
TWiV reviews considerations and perspectives on phage therapy, and the Nobel Prize-winning discovery of hepatitis b virus. Hosts: , , , and Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV Immune 100 WHO global expert committee: (News-Medical) Considerations on (Nat Comm) What is ? (CDC) History of phage therapy (, ) JAMA Viruses that (can) make you well () The InVinceable TWiV () Blumberg Particles associated with (Nature) HBV vaccination...
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TWiV 1278: Clinical update with Dr. Daniel Griffin
This Week in Virology
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the rise in norovirus infections, contamination of infant formula and botulism outbreak, confusion and response to the CDC’s ACIP decision to reverse the recommendation for a birth dose of the hepatis B virus vaccine and how states in the Northwest and Northeast are responding as well as some insurance companies, then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, South Carolina’s imposed quarantine of...
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TWiV 1277: Vaccine talk with Jake Scott
This Week in Virology
Infectious diseases physician Jake Scott returns to TWiV to discuss the dangerous anti-vaccine policies being established in the US and what RFK Jr. and his associates get wrong. Hosts: , , and Angela Mingarelli Guest: Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV Vaccine RCT (CIDRAP) What RFK Jr gets (Conversation) RFK Jr’s case (STAT) Too many kids’ vaccines? (STAT) Timestamps by Ramsey. Thanks! Weekly Picks Angela – Angela Palmer, science meets art...
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TWiV 1276: Clinical update with Dr. Daniel Griffin
This Week in Virology
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the positive side effect of the shingles vaccine on dementia outcomes and how one dose of the HPV vaccine is non-inferior to two doses, but are dismayed about the FDA’s secrecy around the inflammatory statement that the COVID-19 vaccine is linked to the death of 10 children. Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, effectiveness of maternal administration of the RVS vaccine or the...
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TWiV 1275: An amazing sequence and a gutsy therapy
This Week in Virology
TWiV explains the Nobel Prize-winning discovery of pre-mRNA splicing, and engineering bacteriophage to deliver proteins to the human intestine. Hosts: , , and Subscribe (free): , , Become a of TWiV! Links for this episode at MicrobeTV Immune 100 of adenovirus mRNA (PNAS) An in adenovirus mRNA (Cell) Nobel Prize for (Nobel) A in adenovirus late mRNAs (Cell) with Phillip A. Sharp (ASM) Protein production in the gut by (Nat Biotech) phage T4 (Curr Op Virol) Timestamps by Ramsey....
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TWiV 1274: Clinical update with Dr. Daniel Griffin
This Week in Virology
In his weekly clinical update, Dr. Griffin and Vincent Racaniello wish everyone a Happy Thanksgiving and then decry appointment of the Louisiana State surgeon general as deputy chief of the CDC, the 3 children’s deaths during this fall’s pertussis outbreak, the Marburg virus outbreak in Ethiopia, results of the phase 1 safety trial for the novel poliovirus vaccines nOPV1 and nOPV3, and the first human death from H5N5 influenza virus infection in the US this fall, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the...
info_outlineIn his weekly clinical update, Dr. Griffin and Vincent Racaniello wish everyone a Happy Thanksgiving and then decry appointment of the Louisiana State surgeon general as deputy chief of the CDC, the 3 children’s deaths during this fall’s pertussis outbreak, the Marburg virus outbreak in Ethiopia, results of the phase 1 safety trial for the novel poliovirus vaccines nOPV1 and nOPV3, and the first human death from H5N5 influenza virus infection in the US this fall, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, effectiveness of the cell or egg based flu or the mRNA vaccines, immunogenicity and efficacy of updated COVID-19 vaccines, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, immune and cognitive dysfunction during long COVID and contacting your federal government representative to stop the assault on science and biomedical research.
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Links for this episode
- Anti-science Movement: Deputy director of CDC (X:Louisiana Office of the Surgeon General)
- CDC’s new deputy director is vocal critic of vaccines, advocated for ivermectin (CIDRAP)
- Whooping cough cases on the rise in Texas (FOX4: KDFW)
- Third infant in Kentucky dies of whooping cough as national cases stay high for second year in a row (CIDRAP)
- More than 25,000 whooping cough cases reported this year as Kentucky records 3rd infant death (ABC News)
- Vaccination Coverage and Exemptions among Kindergartners (CDC: SchoolVaxView)
- Effects of human papillomavirus (HPV) vaccination programmes on community rates of HPV‐related disease and harms from vaccination (Cochrane Library)
- Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease)
- Safety and immunogenicity of novel live attenuated type 1 and type 3 oral poliomyelitis vaccines in healthy adults in the USA: a first-in-human, observer-masked, multicentre, phase 1 randomised controlled trial (LANCET: Infectious Diseases)
- Washington state resident believed to be the first to die from a rare strain of bird flu (AP News)
- Wastewater for measles (WasterWater Scan)
- Measles cases and outbreaks (CDC Rubeola)
- Tracking Measles Cases in the U.S. (Johns Hopkins)
- Measles vaccine recommendations from NYP (jpg)
- Weekly measles and rubella monitoring (Government of Canada)
- Measles (WHO)
- Get the FACTS about measles (NY State Department of Health)
- Measles (CDC Measles (Rubeola))
- Measles vaccine (CDC Measles (Rubeola))
- Presumptive evidence of measles immunity (CDC)
- Contraindications and precautions to measles vaccination (CDC)
- Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
- Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
- Deaths following vaccination: what does the evidence show (Vaccine)
- Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
- US respiratory virus activity (CDC Respiratory Illnesses)
- Respiratory virus activity levels (CDC Respiratory Illnesses)
- Weekly surveillance report: clift notes (CDC FluView)
- Superior Effectiveness and Estimated Public Health Impact of Cell- Versus Egg-Based Influenza Vaccines in Children and Adults During the US 2023–2024 Season (Infectious Diseases and Therapy)
- Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine(NEJM)
- ACIP Recommendations Summary (CDC: Influenza)
- Types of Influenza Viruses (CDC: Influenza (flu))
- Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA)
- RSV: Waste water scan for 11 pathogens (WastewaterSCan)
- Respiratory Diseases (Yale School of Public Health)
- US respiratory virus activity (CDC Respiratory Illnesses)
- RSV-Network (CDC Respiratory Syncytial virus Infection)
- Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
- Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
- Estimating Risk of Guillain-Barré Syndrome in US Medicare-Enrolled Older Adults Following Medically Attended Respiratory Syncytial Virus Disease (CID)
- FDA Requires Guillain-Barré Syndrome (GBS) Warning in the Prescribing Information for RSV Vaccines Abrysvo and Arexvy: FDA Safety Communication (FDA)
- Brag Sets Off a Chain Reaction — Dr. Oz Takes the Bait, But Fumbles the Math, and Starts Unraveling Mid-Interview (Atlanta BlackStar)
- Waste water scan for 11 pathogens (WastewaterSCan)
- COVID-19 deaths (CDC)
- Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
- COVID-19 national and regional trends (CDC)
- COVID-19 variant tracker (CDC)
- SARS-CoV-2 genomes galore (Nextstrain)
- Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
- Effectiveness of the BNT162b2 and mRNA-1273 JN.1-adapted vaccines against COVID-19-associated hospitalisation and death: a Danish, nationwide, register-based, cohort study (LANCET: Infectious Diseases)
- Immunogenicity of JN.1- and KP.2-Encoding mRNA COVID-19 Vaccines Against JN.1 Subvariants in Adult Participants (OFID)
- SARS-CoV-2 vaccination and myositis in Norway and Sweden (Rheumatology)
- Where to get pemgarda (Pemgarda)
- EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
- Infusion center (Prime Fusions)
- CDC Quarantine guidelines (CDC)
- NIH COVID-19 treatment guidelines (NIH)
- Drug interaction checker (University of Liverpool)
- Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
- Understanding Coverage Options (PAXCESS)
- Infectious Disease Society guidelines for treatment and management (ID Society)
- Molnupiravir safety and efficacy (JMV)
- Convalescent plasma recommendation for immunocompromised (ID Society)
- What to do when sick with a respiratory virus (CDC)
- Managing healthcare staffing shortages (CDC)
- Anticoagulation guidelines (hematology.org)
- Daniel Griffin’s evidence based medical practices for long COVID (OFID)
- Long COVID hotline (Columbia : Columbia University Irving Medical Center)
- The answers: Long COVID
- Digitally Assessed Long COVID Symptomatology Is Associated With Lymphocyte Mitochondrial Dysfunction and Altered Immune Potential (OFID)
- Evaluation of Interventions for Cognitive Symptoms in Long COVID (JAMA Neurology)
- Reaching out to US house representative
- Letters read on TWiV 1274
- Dr. Griffin’s COVID treatment summary (pdf)
- Timestamps by Jolene Ramsey. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv
Content in this podcast should not be construed as medical advice.