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Brain Ponderings podcast with Dr. Mark Mattson

Conversations with neuroscientists, neurologists, evolutionary biologists, anthropologists, computer scientists, and others that ponder the brain. Here are a few of the questions that BRAIN PONDERINGS will tackle: How have brains evolved to enable success in diverse environments? How does the brain develop in the womb and in early life? What are the mechanisms responsible for learning and memory, language, and emotions? How does the brain respond to life’s challenges? In what ways does the brain influence the body and vice-versa? What is known about the causes of psychiatric, neurodegenerative, and other brain disorders? What new technologies are being developed to treat neurological disorders? How do naturally occurring and man-made chemicals affect the brain? How can gene therapy, cell regeneration, and brain stimulation be used for brain disorders? What are the boundaries between ethical and unethical neuroscience research?

info_outline Alex Kwan: Cutting-Edge Technologies Reveal How Psilocybin Rewires the Brain’s Neural Networks 01/27/2026
info_outline Neurobiology of Aging Lecture #5 – Mechanisms by Which Lifestyle Choices Affect Brain Aging 01/13/2026
info_outline Andrew Pieper: Recent Evidence that Advanced Alzheimer’s Disease May be Reversible 01/06/2026
info_outline Neurobiology of Aging Lecture #4: Aging and Neurodegenerative Disorders; AD, PD, ALS, and FTD. 12/30/2025
info_outline Tomás Ryan: Competition Between Memory Engrams and The Importance of Forgetting 12/23/2025
info_outline Shuying Sun: RNA Dysregulation in Neurodegenerative Disorders – From Mechanisms to New Therapies 12/16/2025
info_outline Neurobiology of Aging Lecture #3: mTOR, Functional and Structural Alterations, and Biomarkers 12/10/2025
info_outline Neurobiology of Aging Lecture 2: Cellular and Molecular Hallmarks of Brain Aging 12/10/2025
info_outline Neurobiology of Aging Lecture Series: #1 – Theories, Comparative Biology, and Animal Models of Aging 12/10/2025
info_outline Norm Haughey: Membrane Sphingomyelin and Ceramides Abnormalities in Alzheimer’s and Other Diseases 12/02/2025
info_outline David Gutmann – Cancer Neuroscience and the Sociobiology of Brain Tumors 11/18/2025
info_outline Ray Dorsey: Environmental Toxins and Parkinson’s Disease – Evidence and What to Avoid 11/12/2025
info_outline Ai Yamamoto: “ALFY” Cleanses Neurons of Pathological Proteins to Counteract Degenerative Diseases 10/29/2025
info_outline Marco Capogrosso – Spinal Cord Stimulation for Recovery of Function After Stroke or Trauma 10/21/2025
info_outline Dayu Lin: Neural Circuits and Neurochemicals for Aggression, Sexual, and Parental Behaviors 10/13/2025
info_outline Scott Ayton: Iron, Brain Health, Parkinson’s and Alzheimer’s Diseases – A Delicate Balance 10/07/2025
info_outline Erik Musiek: Brain Cell Circadian Clock Proteins in Neuroplasticity, Aging, and Alzheimer’s Disease 09/24/2025
info_outline Georgia Hodes: Sex Differences in Responses to Stress and Vulnerability to Neurological Disorders 09/11/2025
info_outline Marian Joëls and Ron de Kloet: How the Brain Responds to Stress in Health and Mental Disorders 09/01/2025
info_outline Josh Helman: Multipronged Approaches for Preventing and Treating Alzheimer’s Dementia 08/19/2025
info_outline Grace (Beth) Stutzmann: Pivotal Role for Calcium in Brain Aging and Alzheimer’s Disease 08/14/2025
info_outline Andrew Dillin – Stress and Aging: Mitochondria are Hubs of Information Flow in and Between Cells 08/05/2025
info_outline Marc Freeman – How Astrocytes Control Neural Circuits in Brain Development, Plasticity, and Disease 07/29/2025
info_outline Polina Shichkova: Metabolic and Biophysical Modeling of Breakdown and Repair of the Aging Brain 07/22/2025
info_outline Corinde Wiers: The Potential of Ketone-Based Interventions for the Treatment of Addiction 07/15/2025
info_outline Henning Fenselau – Neural Circuits Controlling Appetite and Energy Metabolism and GLP-1 Actions 07/07/2025
info_outline Tessa Montague: Disappearing Act - How the Brain Controls Camouflage in Cuttlefish and Octopuses 07/01/2025
info_outline Jonathan Long: Lactate-Phe and Ketone-Phe: Exerkines and Fastokines for Brain Health and Plasticity? 06/24/2025
info_outline Carlos Matute: Brain White Matter in Health, Endurance Exercise, and Disease 06/17/2025
info_outline Michael Kreutz: Amazing Nanomachines in Synapses that Keep Brains Healthy and Wise 06/10/2025
 
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