Efficient Trial Design; ‘evidence’ in the era of ‘Big Data’ | Dingle 2022
Release Date: 11/21/2022
GLP-1 Receptor Agonists and Anaesthesia: Aspiration Risk in a UK Multicentre Study
TopMedTalk
Recorded in Prato, Italy at the 8th Collaborative Clinical Trials in Anesthesiology meeting. Desiree Chappell and guest co-host Mark Priestley interview Professor Karim El-Boghdadly, Consultant Anaesthetist and Clinical Lead for Theatres, Anaesthesia, and Peri-operative Medicine at Guy's and St Thomas' NHS Foundation Trust, as well as an Honorary Reader at King's College London about the perioperative implications of GLP-1 receptor agonists. El-Boghdadly explains expanding GLP-1 use, delayed gastric emptying, and why early “hold for a week” guidance may be impractical. He describes a UK...
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TopMedTalk Classic: Detecting and managing frailty
TopMedTalk
This month’s TopMedTalk Classic was originally aired in 2019 but remains very relevant today. Presented by Dr Jugdeep Dhesi, Clinical Lead, POPS and Consultant Geriatrician, Guys and St Thomas' NHS Trust, and an expert on frailty. This talk explores how our understanding and discussion has improved regarding a condition that is still yet to have a clear, universally accepted, definition. How do we build a patient's physical reserve? What is the best way to conceptualise frailty? Are there any universal treatments available? TopMedTalk’s back catalogue contains over 2000 episodes covering...
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EBPOM Ireland 2026: Pre-Hospital Care in Mountain Rescue and at Sporting Events
TopMedTalk
Recording from TopMedTalk at EBPOM in Dingle, Ireland, Kate Leslie and Imogen Fecher-Jones interview Oliver Pratt, Consultant Anaesthetist at Salford Royal Hospital, Chair of the Primary FRCA Structured Oral Examinations for the Royal College of Anaesthetists, and a Medical Officer for the Kinder Mountain Rescue Team and Joe Cosgrove, a Consultant in Anaesthesia and Intensive Care Medicine at the Newcastle upon Tyne Hospitals NHS Foundation Trust, a Primary FRCA Examiner for the Royal College of Anaesthetists, and the Critical Care Outreach Lead specializing in advance care planning. He is...
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Perioperative Profiles: Duminda Wijeysundera
TopMedTalk
This month’s Perioperative Profile features Duminda Wijeysundera, Professor in the Department of Anesthesiology and Pain Medicine and IHPME at the University of Toronto, and a Staff Physician at St. Michael's Hospital, who holds the Endowed Chair in Translational Anesthesiology Research, serves as Head of Science at SPHERE, acts as a Senior Adjunct Scientist at ICES, and is a Trustee for the International Anesthesia Research Society (IARS). He describes growing up across Sri Lanka, the US, Singapore, and Canada, and how adaptability and cultural sensitivity shaped him; he entered medicine...
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EBPOM London 2026: Enhanced Postoperative Care Units (EPOCs)
TopMedTalk
Recorded at the Evidence Based Perioperative Medicine (EPBOM) World Congress in London, this TopMedTalk episode, presented by Andy Cumpstey, features Guy Ludbrook, Professor of Anaesthesia and Head of Acute Care Medicine at the University of Adelaide and resident Georgia Cadzow, discussing the Perioperative Quality Initiative (POQI) POQI is a not-for-profit that uses a formal Delphi process to distill evidence and expert consensus into publishable clinical recommendations on topics such as perioperative hypotension, acute kidney injury, delirium, health economics, and fluid therapy. Georgia...
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Regulating AI in Perioperative Medicine: Data, Trust, and Evidence
TopMedTalk
Today’s TopMedTalk AI podcast was recorded at the Association of Anaesthetists of Great Britain and Ireland in London. It features Andy Cumpstey and Desiree Chappell and their guests, John Whittle, honorary associate professor of Perioperative medicine at University College London and Duncan McPherson, Head of the clinical team at QMD Services and Anesthesiologist and Honorary Professor at University College London. We discuss how early AI research shares core requirements with other research—especially data safety and governance—while medical device regulation applies the same legal...
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SOAP: Caesarean Pain, Patient Voice and System Change
TopMedTalk
At the 58th Society for Obstetric Anesthesia and Perinatology (SOAP) meeting in Montreal, TopMedTalk hosts Mike Grocott and Desiree Chappell interview Heather Nixon, SOAP immediate past president and Section Chief for Obstetric Anesthesiology; Section Chief for Simulation, Education, and Training Department of Anesthesiology University of Illinois, about SOAP’s educational mission, governance, outreach, and special interest groups. Nixon describes her focus on intraoperative pain during caesarean delivery after a sentinel event and how listening to patient narratives, including The...
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ANZCA ASM: Neuroscience, neuroimaging and practice in pain medicine
TopMedTalk
Recorded at ANZCA and the Faculty of Pain Medicine’s Annual Scientific Meeting in Auckland, TopMedTalk hosts Andy Cumstey and Kate Leslie interview visiting pain research leaders, Professor Irene Tracey, the Vice-Chancellor of the University of Oxford and Professor Lesley Colvin, the Chair of Pain Medicine at the University of Dundee and an Honorary Consultant in Anaesthesia and Pain Medicine at NHS Tayside. They discuss how thinking has shifted from chronic pain as a simple transition from acute pain, to a distinct disease with separate mechanisms and early “pre-vulnerability” factors...
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EBPOM London: The National Clinical Audit for Major Elective Surgery
TopMedTalk
At EBPOM 2026 live from the British Library in London, Joff Lacy and Imogen Fecher-Jones speak with Malcolm West and Tim Baker, clinical co-leads for the National Clinical Audit of Perioperative Care (NCAPC), an NHS England mandated and HQIP-funded initiative managed by the Royal College of Anaesthetists to audit major elective surgery in England and publicly funded Jersey. They outline the audit’s denominator (major surgery with anaesthetist involvement and >24-hour stay), year-one focus cohorts (thoracic, major gynaecology, major hip/knee orthopaedics, and lower GI/colorectal surgery),...
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TopMedTalk Classic: Managing Perioperative Risk in Frail Patients
TopMedTalk
This month’s TopMedTalk Classic has been digitally remastered for you and we’ve added the Q&A which wasn’t part of the original podcast. We’re featuring a talk first broadcast in 2018, featuring BobbieJean Sweitzer, Systems Director, Preoperative Medicine, Inova Health, Falls Church, Virginia, and Professor of Medical Education, University of Virginia. BobbieJean discusses whether perioperative risk in frail patients can be managed, emphasizing that current risk tools underweight frailty and functional outcomes. Using cases and data from U.S. nursing home residents, she highlights...
info_outlineThis fundamental conversation is given a fresh perspective during one of the stand out moments of the recent Evidence Based Perioperative Medicine (EBPOM) Dingle conference. How do we define evidence in the era of big data? Can we further improve the speed at which we do trials and yet still gather reliable data? In the wake of COVID-19 what new innovations can be made to how we trial and test vital medical help?
Chaired by Ramani Moonesinghe, OBE, Professor of Perioperative Medicine at University College London, Consultant in Anaesthetics and Critical Care Medicine at UCL Hospitals, this piece features; Mark Edwards, Consultant in Anaesthesia & Perioperative Medicine, University Hospital Southampton, Honorary Senior Clinical Lecturer, University of Southampton, Mike Grocott, Professor of Anaesthesia and Critical Care Medicine, University of Southampton and Matt Wilson, Anesthetist, UCL Hospitals and University College London and a PhD candidate.