Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Saint Augustine of Hippo (354โ430 CE), a prominent theologian, philosopher, and bishop in Roman North Africa, profoundly influenced Western Christianity and philosophy. Known for works like Confessions, The City of God, and On Christian Doctrine, he developed doctrines on original sin, grace, just war, and ecclesiology. His thoughts shaped medieval theology, inspired Protestant Reformers, and continue to impact Christian teachings.
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๐จ Just out in JAMA! ๐ก PanEcho, a multitask AI model trained on over 1.2 million echo videos, can automate complete echocardiographic interpretation โ from LVEF to valvular disease โ with diagnostic AUCs up to 1.00 and MAE as low as 4.2%. ๐ Validated across international cohorts, including point-of-care settings, this tool could redefine access, accuracy, and efficiency in cardiac imaging. ๐ซ๐ค A major leap toward AI-assisted cardiovascular diagnostics. ๐ #AIinMedicine #Cardiology #EchoRevolution #PanEcho #DigitalHealth #JAMA #MachineLearning #CardioAI...
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๐จ New insights from cancer neuroscience! ๐ง ๐งฌ A groundbreaking Nature study reveals that cancer cells can steal mitochondria from nearby neurons via tunneling nanotubes โ supercharging their metabolism, stemness, and metastatic potential ๐ช๏ธ๐ฅ Using a clever tool called MitoTRACER, researchers traced this โmitochondrial hijackโ across cancers (breast, prostate, melanoma) and showed that recipient cells were more likely to seed distant metastases โ especially in the brain ๐งณ๐ง ๐งช Targeting this nerveโtumor energy axis may open new doors to stop...
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๐ง ๐ Cognitive decline and cardiovascular disease often go hand in hand โ but they donโt have to spiral together. In our latest breakdown, we explore how cardiologists can detect, manage, and even improve cognitive impairment through smart risk factor control, lifestyle changes, and a multidisciplinary approach. From MoCA to memantine, TAVR to team-based care โ itโs time to connect the mind and the heart. ๐ Evidence-based strategies ๐ฉบ Practical tools for clinicians ๐ก Insights from JACCโs state-of-the-art review ๐ Letโs build heart-smart,...
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐ง ๐ Can vaccines protect the mind? New research suggests that AS01-adjuvanted vaccines like Shingrix and Arexvy may reduce the risk of dementiaโpossibly by stimulating immune pathways like IFN-ฮณ and TLR4, not just by preventing infection. ๐ In a large US-based EHR study, those who received the RSV or shingles vaccine had a significantly lower 18-month dementia risk than flu-vaccinated peers. ๐ฌ The common thread? The AS01 adjuvant. ๐ก๏ธ Could this be a new frontier in neuroprotection? Letโs discuss. #Vaccines #Dementia #RSV #AS01 #Neuroimmunology...
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New Insights from the DanGer Shock Trial! ๐ซ๐ก Can early left ventricular unloading with a microaxial flow pump (mAFP) save lives in STEMI-related cardiogenic shock? This compelling substudy shows that mAFP not only boosts cardiac output and power, but also reduces pulmonary pressuresโall while using less pharmacologic support. ๐๐ ๐งช Native CO improved steadily over 48 hours, hinting at myocardial recovery. ๐ PAC data gives us a front-row seat to the physiology behind the survival curves. ๐ฌ The editorial dives deeper: timing, technique, and future questions....
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๐จ New Breakthrough in Type 2 Diabetes Care! ๐๐งฌ The ACHIEVE-1 trial shows that Orforglipron, a once-daily oral, nonpeptide GLP-1 receptor agonist, delivers significant reductions in HbA1c and body weightโwithout injections and with minimal restrictions! ๐๐ ๐จโโ๏ธ 559 patients across 5 countries โฑ๏ธ 40 weeks, 3 dosing arms (3, 12, 36 mg) ๐ HbA1c โ by up to 1.48%, weight โ up to 7.6% โ No severe hypoglycemia ๐ Mild GI side effects during dose titration This is a potential gamechanger for early T2DM careโsimple, effective, and...
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๐จ Frailty matters โ even in the cath lab! ๐ง๐ซ A new NCDR registry analysis of 1.3M+ older adults shows a clear gradient: as frailty increases, so do complications, mortality, and procedural risks during PCI. Severely frail patients faced a striking 20.3% in-hospital mortality and >50% mortality with cardiogenic shock. ๐ง Itโs time to treat frailty as a vital sign โ embedded in our workflow, guiding shared decisions, and shaping post-PCI care. ๐ Letโs bring team-based, geriatric-informed strategies to the forefront of interventional cardiology....
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๐จ Major breakthrough in obesity pharmacotherapy! The REDEFINE-1 & REDEFINE-2 trials show that once-weekly CagriSema (Cagrilintide + Semaglutide) delivers up to 20% weight loss in people with obesityโand significant glycemic improvements in those with type 2 diabetes. ๐๐ ๐ Global, double-blind RCTs โ๏ธ >90% lost โฅ5% body weight ๐ฉบ SBP โ, QoL โ, prediabetes reversed in 88% โ ๏ธ GI side effects common but mostly mild ๐ก CagriSema is redefining the weight loss frontierโwith dual satiety and metabolic action. #Obesity #GLP1 #Cagrilintide #Semaglutide...
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๐ฅ New Study Alert! ๐ฉบ Wildfire smoke isnโt just a respiratory threat โ itโs taking a toll on the heart, especially in older adults. ๐ A nationwide Medicare cohort (~22M) shows that long-term exposure to wildfire-specific PM2.5 is linked to significantly higher heart failure risk โ more so than urban pollution. ๐ Vulnerable groups โ women, Medicaid-eligible individuals, and low-income communities โ face the highest burden. ๐ซ๏ธ Tiny particles. Massive impact. ๐ Read the study: Hao et al, JACC July 2025 #Cardiology #AirPollution #WildfireSmoke...
info_outline๐ฅ New Study Alert! ๐ฉบ
Wildfire smoke isnโt just a respiratory threat โ itโs taking a toll on the heart, especially in older adults.
๐ A nationwide Medicare cohort (~22M) shows that long-term exposure to wildfire-specific PM2.5 is linked to significantly higher heart failure risk โ more so than urban pollution.
๐ Vulnerable groups โ women, Medicaid-eligible individuals, and low-income communities โ face the highest burden.
๐ซ๏ธ Tiny particles. Massive impact.
๐ Read the study: Hao et al, JACC July 2025
#Cardiology #AirPollution #WildfireSmoke #HeartFailure #EnvironmentalJustice #PM25 #PublicHealth #Epidemiology