3366: Harvard Medical School: The Promise and Peril of CRISPR With Neal Baer
Release Date: 07/31/2025
3369: Precisely Explains Why AI Fails Without Data Integrity
Tech Talks Daily
In today’s episode of Tech Talks Daily, I sat down with Andy Bell, Head of Data Product Management at Precisely, to explore a challenge that many organizations continue to underestimate: the role of data integrity in AI strategies. With only 12 percent of businesses expressing confidence in the quality of their AI data, it's clear that the rush to implement AI is often outpacing the readiness of the data that supports it. Andy and I unpack what happens when enterprises leap into generative or agentic AI without addressing foundational data issues. From hallucinations to bias to unreliable...
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3368: Nerdio Builds a Remote-First Unicorn Focused on Azure Optimization
Tech Talks Daily
In this episode of Tech Talks Daily, I sat down with Joseph Landes, co-founder and Chief Revenue Officer at Nerdio, to explore how one conversation at a Microsoft conference led to a billion-dollar cloud automation company. From his 23-year career at Microsoft to building a fully remote team now supporting over five million users, Joseph’s story blends strategic risk-taking with deep industry insight. We unpacked how Nerdio grew from a startup idea in 2018 to a company that just secured 500 million dollars in Series C funding. Joseph walked me through the early days of building the business...
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3367: CGS Reinvents Workplace Training With AI-Powered Role Play
Tech Talks Daily
The training room is changing, and it's not going back. In this episode, I sat down with Phil Friedman, the founder and CEO of CGS Inc., to explore how AI, avatars, and immersive simulations are rewriting the playbook on workplace training. With over four decades at the helm of CGS—a company he built from scratch after immigrating to the US—Phil brings a perspective shaped by both technological evolution and global business experience. The heart of our conversation centered on Cicero, CGS’s AI-driven platform that blends artificial intelligence with extended reality to create dynamic,...
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3366: Harvard Medical School: The Promise and Peril of CRISPR With Neal Baer
Tech Talks Daily
When we think about gene editing, the conversation often feels trapped between scientific journals and ethical debates too complex for public forums. In this episode, I spoke with Neal Baer, a rare voice who bridges both worlds. Known to many as an award-winning television showrunner for series like ER, Law & Order SVU, and Designated Survivor, Neal is also a Harvard-trained physician and co-director of the Media, Medicine, and Health program at Harvard Medical School. His latest project brings all of that experience together in a new collection of essays that explores the promise and...
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3365: BlackLine on Why AI Is Changing the Nature of Tech Leadership
Tech Talks Daily
In this episode of Tech Talks Daily, I welcomed back Sumit Johar, CIO at BlackLine, for a timely conversation about how AI is transforming finance operations from the inside out. When we last spoke earlier this year, AI was still in the early stages of enterprise experimentation. Just a few months later, everything has shifted. Sumit shared how AI has moved well beyond pilot programs and into a space where business leaders themselves are actively requesting implementations. What stood out in our conversation was how this change has reshaped the relationship between CIOs and CFOs. The...
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3364: MongoDB Simplifies AI Development With Integrated Vector Search
Tech Talks Daily
In this episode of Tech Talks Daily, I sat down with Boris Bialek, VP and Field CTO at MongoDB, for a conversation that moved well beyond databases. As AI continues to accelerate across sectors, MongoDB is positioning itself at the intersection of modern data architecture and intelligent application development. Boris shared how his team is simplifying AI adoption for enterprises, with a clear focus on real-world outcomes, developer productivity, and global inclusion. We began by exploring MongoDB’s recent acquisition of Voyage AI. This move extends MongoDB's native capabilities into vector...
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3363: ABB on Building a Smarter and More Resilient Power Grid
Tech Talks Daily
When we think about innovation in technology, power grids rarely enter the spotlight. Yet, they are the foundation for everything from artificial intelligence to electric vehicles and data centers. In this episode, I spoke with Adrian Guggisberg, President of the Smart Power Division at ABB, to unpack the evolving role of electrical power distribution in a world shifting rapidly toward digital infrastructure and clean energy. Adrian joined me from Zurich to share how ABB is helping grid operators navigate an increasingly complex landscape. With rising pressure from extreme weather, surging...
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3362: Inside LVT’s Mission to Deter Crime Before It Happens With Tech
Tech Talks Daily
In a digital-first world where cybersecurity often dominates headlines, the conversation around physical security can sometimes feel like an afterthought. But what if technology could bring a new level of intelligence, proactivity, and efficiency to protecting real-world environments? In this episode, I sat down with Ryan Porter, co-founder and CEO of LVT, to learn how his team is reshaping physical security through innovation rooted in both technology and field experience. What began in Ryan’s garage as a way to monitor construction projects through live video has evolved into a powerful...
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3361: Why AidKit Built a Tech Platform for Equitable Aid Distribution
Tech Talks Daily
In today’s episode of Tech Talks Daily, I connected with Brittany Christenson, CEO of AidKit, to explore how cutting-edge technology is being used not to disrupt markets or chase margins, but to deliver real, measurable social impact. AidKit is a public benefit corporation building infrastructure that helps vulnerable communities access aid quickly, securely, and with dignity. While many tech conversations orbit around scale and efficiency, Brittany brings a different kind of energy, one grounded in values, user empathy, and purpose-built innovation. She shared how AidKit’s journey began...
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3360: How Certinia Is Bringing AI Agents Into Professional Services at Scale
Tech Talks Daily
When we talk about the future of enterprise software, AI is front and center. But behind the buzzwords, real transformation is happening in how businesses plan, execute, and deliver professional services. In this episode, I sat down with Raju Malhotra, Chief Product and Technology Officer at Certinia, to explore how AI is shifting from theory to practice in high-scale environments. Certinia, a native ISV on Salesforce, is helping global tech and service firms like Cisco, Siemens, and PwC automate their services operations. With over two million users and six million active projects, the...
info_outlineWhen we think about gene editing, the conversation often feels trapped between scientific journals and ethical debates too complex for public forums. In this episode, I spoke with Neal Baer, a rare voice who bridges both worlds.
Known to many as an award-winning television showrunner for series like ER, Law & Order SVU, and Designated Survivor, Neal is also a Harvard-trained physician and co-director of the Media, Medicine, and Health program at Harvard Medical School. His latest project brings all of that experience together in a new collection of essays that explores the promise and peril of CRISPR gene-editing technology.
Neal takes us on a journey that begins with his time as a medical resident treating a young sickle cell patient, and leads to a much broader conversation about science, ethics, and storytelling. We discuss how CRISPR is already being used to cure diseases like sickle cell, and how companies are now exploring gene edits that promise permanent reductions in cholesterol. But the real power of this discussion is not just in what CRISPR can do, but in what we still don’t fully understand about its long-term impact.
The conversation moves into difficult territory—unintended mutations, germline editing, the risk of pathologizing human diversity, and the slippery slope of “enhancement” where only those with access can benefit. Neal raises critical questions about the social cost of deciding which conditions should be “fixed” and who gets to make that call. We also dive into the lack of political and regulatory oversight, and why a global framework, not just scientific advancement, is urgently needed.
This episode offers a powerful reminder that the future of CRISPR shouldn’t be left solely to researchers or startups. It demands wide engagement, from classrooms to policymaking, and inclusive voices that challenge how we define progress.
How should we decide what counts as improvement when the very definition of being human is at stake?