New Hope for Male Infertility: Can Isotretinoin (Accutane) Restore Sperm Production? with Dr. Paul Turek
Release Date: 12/17/2025
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In this episode, Dr. Paul Turek and I are talking about the latest research on isotretinoin aka Accutane (a medication traditionally used for acne) and its potential to restore sperm production in men who previously had no options. Our discussion explores the science behind this therapy, the real-world impact for patients, and what this means for the future of male fertility treatments. We also touch on the broader landscape of advances in male reproductive health, including the role of AI and the importance of early, expert evaluation. In this episode, we cover: The story behind the...
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info_outlineIn this episode, Dr. Paul Turek and I are talking about the latest research on isotretinoin aka Accutane (a medication traditionally used for acne) and its potential to restore sperm production in men who previously had no options. Our discussion explores the science behind this therapy, the real-world impact for patients, and what this means for the future of male fertility treatments. We also touch on the broader landscape of advances in male reproductive health, including the role of AI and the importance of early, expert evaluation.
Read the full show notes on Dr. Aimee's website.
In this episode, we cover:
- The story behind the recent study on isotretinoin and male infertility
- How vitamin A derivatives play a crucial role in sperm production
- The specifics of Dr. Turek’s clinical trial with isotretinoin and its promising results
- Safety considerations and misconceptions about isotretinoin use in men
- How this therapy fits into the broader landscape of male fertility treatments
- The future of male fertility, including AI-driven advances and at-home diagnostics
- Practical advice for men and couples navigating infertility
Resources:
- Turek Clinic
- Isotretinoin Study at NIH website
- Talk with Turek Podcast
- Contact Turek Clinic: San Francisco (415-392-3200), Los Angeles (310-499-9299)
- Egg Whisperer Show on YouTube
- Egg Whisperer Show on Spotify
The next live class call is on Monday, January 12, 2026, at 4 pm PST, where I’ll explain IVF and Egg Freezing, and answer your questions live on Zoom.
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