Sperm Health: A New Test from PS Fertility with guest Jeff Lysiak (PS Detect)
Release Date: 03/11/2026
The Fertility Formula: Hormones, Inflammation, and the Truth About Optimizing Fertility with Dr. Natalie Crawford
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In this episode, I'm joined by one of my favorite fellow fertility doctors - Dr. Natalie Crawford, a board-certified reproductive endocrinologist and infertility specialist, co-founder of Fora Fertility in Austin, Texas, host of the As a Woman podcast, and author of the brand-new book The Fertility Formula. Dr. Crawford's journey into reproductive medicine is deeply personal: after experiencing four pregnancy losses and feeling dismissed by the medical system, she channeled that pain into a career dedicated to making sure no patient ever feels unheard or uninformed. Her...
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How to Approach IVF Challenges with guest Dr John Norian
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In this episode of The Egg Whisperer Show, I sit down with the incredible Dr. John Norian, a board-certified OB-GYN and Reproductive Endocrinologist with HRC Fertility in Pasadena and Rancho Cucamonga, California. Dr. Norian completed his residency at Albert Einstein College of Medicine, his fellowship at the NIH, and has served as a Lieutenant Commander in the U.S. Public Health Service, providing care to military families. He is a passionate advocate for anyone on a fertility journey, regardless of relationship status or anatomy. We dive deep into some of the most frustrating and complex...
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How to Create Your Own Personalized IVF Plan
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Today on the podcast, I'm talking all about how you can create your own personalized IVF Plan. Have you ever used Google Maps and been redirected midway via a better route? Alternatively, maybe you’re proactive in managing traffic and go directly to Waze to get you from point A to point B in the most time effective way? These apps are well-loved and widely used because they remove obstacles out of an otherwise potentially painful process, and they do so with data. I bring the beauty of Google Maps into my fertility care by serving as a personal navigator for every one of my patient’s IVF...
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Secondary Infertility
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Secondary infertility affects so many of my patients. In today’s podcast episode, I’m talking about what happens when someone has no trouble getting pregnant for baby number one and then struggles to conceive another child. People in this situation often don’t know what to do because this is so new to them. I’m sharing everything you need to know about secondary infertility: the causes, treatments, and some of my tips. The truth is, secondary infertility is overwhelming and upsetting. You want to make sure that you have people around that support you, so I also encourage you to share...
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New Technology in Egg and Embryo Freezing with guest Dr. Angie Beltsos
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Today on The Egg Whisperer Show, I’m excited to have Dr. Angie Beltsos joining me to talk about new technology in egg and embryo freezing. She is now with Brown Fertility, and formerly the CEO of Vios Fertility Institute. This year, her practice announced that they would be the first to use new technology to freeze and store both eggs and embryos. TMRW Life Sciences offers new advancements for freezing, monitoring, and storing our most precious cells. We also talk about their upcoming app, and her background in fertility medicine. I am really honored to have her on to talk to her about...
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Tracking Your Cycle: What is The Fertility Awareness Method? with author Toni Weschler and Sabrina Nowicki
The Egg Whisperer Show
I'm joined by extraordinary women who are changing the way women understand our fertility cycles: Toni Weschler, internationally respected women's health educator and author of the landmark book Taking Charge of Your Fertility (translated into 12 languages), and Sabrina Nowicki, engineer, product designer, fertility awareness method practitioner, and CEO of Cyclisity - the new app built as the perfect companion to Toni's book. What makes this collaboration even more special? Toni is Sabrina's aunt, and their bond has been at the heart of this project from the very beginning. We...
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Everything You Need to Know About Fibroids and Fertility with Dr. Banafsheh Kashani
The Egg Whisperer Show
Today on The Egg Whisperer Podcast, I'm joined by Dr. Banafsheh Kashani, a fertility doctor from Eden Centers for Advanced Fertility. If you're looking for answers to your fibroid questions, this is the podcast episode for you. As a fibroid and fertility expert, Dr. Bana is sharing all of her knowledge with us about the impact of fibroids on fertility and pregnancy. Tune in and share widely as you will be extremely impressed by her wealth of knowledge on this topic. Would you like to learn about IVF? The next live class call is on Monday, April 20, 2025 at 4pm PST, where Dr. Aimee will...
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Preparing for your Embryo Transfer
The Egg Whisperer Show
On today’s podcast episode, I’m talking about preparing for embryo transfer. I find that it’s helpful to think about embryo transfer the same way you might think about having a very special guest over for dinner. What are you going to do if you have a very special person over? You’re going to make sure everything is absolutely perfect. When it comes to preparing for an embryo transfer, you want to take the same approach. Your metaphorical home in the house analogy is your uterus. The devastation of doing more tests and finding out that something might be wrong that you have to fix is...
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Becoming a Parent Through Embryo Donation with guests EM•POWER with Moxi
The Egg Whisperer Show
I’m so excited to have Maya, Jen, and Gina of Em•power with Moxi back for part two of our discussion about embryo donation! Today, we’re talking all about becoming a parent through embryo donation. Maya became a mother through embryo donation, and she is sharing about the emotional shift that comes with choosing to become a parent to a baby that doesn’t share your DNA. She also talks about some things to consider when you’re deciding if embryo donation is the right choice for you to grow your family. We also talk about genetic counseling, Empower with Moxi’s “Moxi Matching”...
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Everything You Need to Know About Donating Embryos with guests EM•POWER with Moxi
The Egg Whisperer Show
In early 2019, Gina, Jen, and Maya came together as mamas on a mission to transform the landscape of embryo donation. Each of them had a different fertility journey that had a connection to embryo donation, and wanted to make embryo donation better understood, more inclusive, and more accessible. And, they wanted to bridge the gap between reproductive medicine and child well being. I'm so excited to have them on the show. In this episode (which is Part 1 of 2), we're covering donating embryos. Gina and Jen will be talking about options for people who want to donate their embryos, including...
info_outlineI'm thrilled to bring you this conversation about a breakthrough in male fertility diagnostics that's been literally hiding in plain site. In this episode, I'm joined by Dr. Jeff Lysiak, PhD, co-founder and Chief Science Officer at PS Fertility, to discuss phosphatidylserine (PS) and how this critical molecule on sperm is revolutionizing how we diagnose male infertility. Jeff shares the fascinating story of how his research at the University of Virginia led to discovering that PS on the surface of sperm is essential for fertilization and how traditional semen analysis completely misses this vital piece of the puzzle.
Read the full show notes on my website.
This episode addresses a frustration I've experienced for years in my practice: couples with "normal" semen analysis results who still have trouble when it comes to trying to conceive. Research shows that 20-30% of men with normal basic semen analysis could still be infertile, and we've had no way to identify them, until now.
In this episode, we cover:
- What phosphatidylserine (PS) is and why it's critical for sperm to fuse with and fertilize an egg
- The major limitations of standard semen analysis (count, motility, morphology) and why 20-30% of men with "normal" results may still be infertile
- How the PS Detect test works using flow cytometry to assess over 10,000 sperm per sample
- The connection between varicocele and low PS scores—and how varicocelectomy surgery can restore PS levels to normal ranges
- When the PS test should be ordered in a fertility workup and what to do if scores are low
- Early data showing over 30% of men seeking fertility treatment have low PS scores, including those with normal semen analysis
- How this test can prevent women from undergoing unnecessary treatments when the male factor is undiagnosed
Resources:
- PS Fertility website: psfertility.com
- PS Detect at-home test kit
- Nature Communications publication on phosphatidylserine and fertilization
- Dr. Aimee's Supplement Stack
- The TUSHY Method
- OVANAD+ by Theralogix. Use code EGG.
Click here to join Dr. Aimee for The IVF Class.
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Keywords:
male infertility, phosphatidylserine, PS score, PS Detect, male fertility testing, semen analysis limitations, sperm function, fertilization competence, varicocele, unexplained infertility, IUI success rates, male factor infertility, reproductive urology, Jeff Lysiak, PS Fertility, sperm egg fusion, fertility diagnostics, at-home sperm test, idiopathic male infertility, fertility workup, egg whisperer show, Dr. Aimee