Episode 12: Deep Silicon Photon Counting CT for Liver Fat
Radiology Advances Podcast | RSNA
Release Date: 12/17/2025
Radiology Advances Podcast | RSNA
This episode explores a study from Radiology Advances tackling one of AI’s toughest challenges in medical imaging: consistent pancreas segmentation across CT scans. The authors benchmarked multiple models against multi-reader human consensus and introduced a new metric, Fractional Threshold (FT), to measure robustness. Their human-in-the-loop workflow flagged just 5% of cases for expert review, matching human reliability while cutting annotation time 23-fold.
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This episode explores a study from Radiology Advances challenging FDA's acoustic output limits for liver ultrasound elastography for obese patients. The authors tested the exam at a mechanical index of 2.5, well above the 1.9 regulatory ceiling, and found no liver injury using stringent biochemical criteria. The payoff: a 29.2% reduction in measurement variability and 40% fewer failed attempts in obese participants, potentially transforming metabolic dysfunction associated steatotic liver disease screening in the population that needs it most.
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This episode features a cutting-edge study from Radiology Advances exploring Deep Silicon Photon-Counting CT (DS-IPCCT) for liver fat quantification. Using in silico models, the investigational system demonstrated high spectral accuracy, robust material decomposition, and low error rates—potentially overcoming key limitations of conventional CT and MRI.
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This episode explores Radiology Advances research on RadGPT—a hybrid AI system combining image analysis with a language model to interpret knee radiographs. Built on 77,000 images, the system incorporates mandatory human review, dramatically improving diagnostic accuracy and report quality. Host commentary highlights its potential as a diagnostic assistant for trainees and an efficiency tool for experts.
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This episode covers a study from Radiology Advances evaluating deep learning–accelerated MRI across routine neuroradiology exams. Using Siemens’ Deep Resolve, scan times were cut by over 50% without sacrificing diagnostic image quality. Host commentary explores reader preferences, artifacts, and when DL-MRI may be best suited for clinical use.
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This episode discusses a study from Radiology Advances evaluating contrast-enhanced CT as a non-invasive alternative for lung shunt fraction (LSF) estimation in hepatic radioembolization to the current standard, 99mTc-MAA nuclear medicine imaging. The proposed CT-based method showed strong correlation with standard MAA-based LSF, offering a faster, safer, and potentially more accurate planning approach without compromising clinical decision-making.
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This episode covers a study in Radiology Advances evaluating deep learning–accelerated T1 MPRAGE MRI in patients with memory loss. The approach cut scan time by more than half while preserving image quality and measurement accuracy—offering faster, more comfortable imaging for dementia care and longitudinal follow-up.
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This episode spotlights a study from Radiology Advances introducing a fully automated deep learning pipeline for myocardial infarct segmentation on late gadolinium enhancement cardiac MRI. Developed at the Medical University of Innsbruck, the model showed near-perfect agreement with human experts and even outperformed manual segmentations in blinded qualitative review.
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A prospective study evaluates ultrasound-derived fat fraction (UDFF) as a tool to monitor hepatic steatosis after bariatric surgery. Host commentary unpacks how UDFF may offer a non-invasive, accessible, and quantitative alternative to MRI-PDFF and liver biopsy, and highlights UDFF’s clinical potential for routine liver fat surveillance.
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A multi-center study evaluating an AI model for automated CT segmentation of intracerebral hemorrhage, intraventricular hemorrhage, and perihematomal edema. Host commentary highlights how the deep learning tool delivers near-expert accuracy in under 20 seconds—dramatically reducing time and enhancing precision in acute stroke care.
info_outlineThis episode features a cutting-edge study from Radiology Advances exploring Deep Silicon Photon-Counting CT (DS-IPCCT) for liver fat quantification. Using in silico models, the investigational system demonstrated high spectral accuracy, robust material decomposition, and low error rates—potentially overcoming key limitations of conventional CT and MRI.