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If You Start Testosterone, Are You Stuck for Life? (Harvard Urologist Explains)

The Sex Doctors

Release Date: 02/05/2026

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The Sex Doctors

In this episode Dr. Brandon and Dr. Morgentaler talk about whether testosterone therapy is a lifelong commitment and explain why modern research shows testosterone does not drive prostate cancer and can be safely used in many men. 00:38 Debunking Testosterone Myths They start by clearing up the myth that starting testosterone therapy locks men into treatment for life and explain why people can safely stop and restart it. 03:13 Testosterone and Prostate Cancer Research They break down decades of research to show how early misconceptions shaped fear around testosterone and why modern data does...

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In this episode Dr. Brandon and Dr. Morgentaler talk about how stress lowers testosterone and how modern sexual trends like rough sex reflect deeper changes in hormones, mental health, and human connection. 00:33 Impact of Stress on Testosterone and Estrogen They start by explaining how physical and emotional stress interferes with brain signaling, lowers testosterone, and can also reduce estrogen in both men and women. 04:48 Exploring Trends in Rough Sex They discuss why people are having less sex overall while the sex they do have is becoming rougher and more aggressive. 14:05 Brain...

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In this episode, Dr. Morgentaler & Dr. Brandon talk about whether testosterone can be improved naturally, why supplements and diet fall short, and how outdated FDA policies and misconceptions continue to shape testosterone treatment today. 00:38 Testosterone Myths and Realities – Why supplements, diet, and exercise rarely raise testosterone in a meaningful way, and what actually matters instead. 09:33 FDA Panel on Testosterone – Dr. Morgentaler shares key takeaways from presenting expert evidence to the FDA on modern testosterone science. 20:11 Age-Related Health Issues – Why...

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In this episode, Dr. Brandon talks about how early porn exposure, sexual shame, and misunderstood desire shape adult intimacy, and why healthier conversations about sex are critical for real human connection. 02:59 Creating Sexual Tension in Relationships Dr. Marianne Brandon talks about how sexual tension is created through polarity, with openness and vulnerability generating desire rather than weakness. 14:52 Understanding and Addressing Compulsive Sexual Behavior She discusses compulsive sexual behavior as a complex, individualized issue driven by underlying emotional and psychological...

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In this FDA discussion Dr. Abraham Morgentaler talks about how decades of fear and misinformation wrongly linked testosterone therapy to prostate cancer, while modern evidence shows it is safe and may even reduce prostate cancer risk. 00:27 Challenges in Testosterone Therapy – In this FDA discussion Dr. Abraham Morgentaler talks about the stigma, misinformation, and medical resistance that have limited acceptance of testosterone therapy despite patient benefits. 01:11 Prostate Cancer Myths – He talks about the long-standing but false belief that testosterone “fuels” prostate cancer,...

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In this episode, Dr. Brandon and Dr. Morgentaler talk about why many headline-making medical studies are misleading, how media and journals amplify flawed science, and how to think critically about health news without panic. 00:44 Dr. Brandon and Dr. Morgentaler talk about how to tell the difference between asexuality, low sexual desire, stress, and medication effects, and why personal sexual history matters. 05:43 They also talk about why many big, scary medical headlines are misleading, using hormone therapy as a prime example of media-driven misinformation. 18:29 They talk about the...

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In this episode, Dr. Brandon and Dr. Morgentaler talk about how sexual changes with age affect both men and women, what’s normal biologically, and the practical, compassionate ways therapy, mindset shifts, and hormone support can help people stay connected and fulfilled. 00:24 Dr. Brandon and Dr. Morgentaler talk about why sexual changes with age are common, multifaceted, and often misunderstood, and why it’s important to openly discuss the biology behind them. 02:22 They also talk about how women experience changes like decreased lubrication, vaginal atrophy, and reduced sensitivity...

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In this episode, Dr. Brandon and Dr. Morgenthaler talk about the concept of “quiet quitting” in marriages, why long-term relationships can lose intimacy, and practical ways couples can reconnect, communicate, and restore closeness in their relationship. 00:26 Understanding 'Quiet Quitting' in Marriage – Dr. Brandon & Dr. Morgentaler define “quiet quitting” in marriage and why it’s becoming common. 01:48 Listener Question: Erection Issues and Solutions – They offer practical tips for condom-related erectile challenges and anxiety. 15:24 Rising Trends in Sexual Inactivity...

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In this episode, Dr. Brandon and Dr. Morgentaler talk about how emerging research suggests testosterone therapy may not only be safe but could actually help protect against aggressive prostate cancer, while also touching on practical approaches to maintaining sexual connection at midlife. 00:34 Addressing Listener Questions on Sexual Connection – Dr. Brandon and Dr. Morgentaler discuss practical, therapist-friendly strategies for couples looking to gently reboot intimacy and improve sexual connection at midlife. 04:17 Introduction to Testosterone and Prostate Cancer – The hosts introduce...

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More Episodes

In this episode Dr. Brandon and Dr. Morgentaler talk about whether testosterone therapy is a lifelong commitment and explain why modern research shows testosterone does not drive prostate cancer and can be safely used in many men.

00:38 Debunking Testosterone Myths
They start by clearing up the myth that starting testosterone therapy locks men into treatment for life and explain why people can safely stop and restart it.

03:13 Testosterone and Prostate Cancer Research
They break down decades of research to show how early misconceptions shaped fear around testosterone and why modern data does not support those claims.

18:09 Testosterone’s Role in Prostate Health
They explain how testosterone functions as a normal requirement for prostate tissue and why adequate levels do not cause cancer growth.

21:04 Reevaluating Testosterone in Prostate Cancer Treatment
They discuss why testosterone is being reconsidered even in certain prostate cancer cases and how newer studies challenge long-held medical assumptions.

25:17 Emerging Treatments and Future Directions
The Dr's look ahead at evolving treatment approaches, ongoing research, and how updated evidence may change future care for men with low testosterone and prostate cancer.

Resources:
Morgentaler, A., & Traish, A. M. (2024). Testosterone does not drive prostate cancer: Introducing the framework of testosterone adequacy versus inadequacy. Journal of Urology.

Morgentaler, A., & Traish, A. M. (2009). The saturation model of testosterone and prostate cancer. European Urology.

Huggins, C., & Hodges, C. V. (1941). Early studies on testosterone and prostate cancer. Cancer Research.

TRAVERSE Trial Investigators. (2023). Testosterone replacement therapy and prostate cancer outcomes. New England Journal of Medicine.

Denmeade, S. R., et al. (2015). Bipolar androgen therapy (BAT) in advanced prostate cancer. Science Translational Medicine.

With Dr. Abraham Morgentaler and Dr. Marianne Brandon

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