Longevity Doctors Are Fixing What Medicine Got Wrong (ft. Drs. Yurth & Husain) | SNH Podcast #133
Health Optimization Medicine Podcast
Release Date: 07/23/2025
Why You're Frozen in Survival Mode: Understanding CDR | HOMe Podcast #025
Health Optimization Medicine Podcast
In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, and Jodi Duval sit down to discuss what happens when the body's cellular defense systems remain activated after the original threat has passed. Fatigue and brain fog are often treated as problems that require more stimulation, more exercise, or more supplements. But what if low energy is sometimes an adaptive response? The HOMeHOPe faculty explores the Cell Danger Response, how mitochondria and purinergic signaling respond to threats, and why pushing harder can sometimes work...
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The Real Cause of Endotoxemia: Leaky Gut Explained | HOMe #023
Health Optimization Medicine Podcast
In this episode of the Health Optimization Medicine Podcast, Boomer Anderson, Dr. Allen Bookatz, Dr. Ted Achacoso, and Dr. Jup Kuipers explore a misunderstood cause of chronic fatigue and leaky gut: the bioenergetic failure of your colonocytes. While many practitioners throw random probiotic strains and anti-inflammatory herbs at gut issues, metabolomic research shows this approach fails to address the root problem. The team explains how a starved microbiome forces gut cells to switch energy systems, leaking oxygen into the colon, destroying strict anaerobes, and allowing endotoxins to flood...
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Can Creatine Protect the Brain from Sleep Deprivation? | HOMe Podcast #024
Health Optimization Medicine Podcast
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Allen Bookatz, and Dr. Jup Kuipers explore how acute sleep deprivation affects brain energy metabolism and whether creatine monohydrate can help preserve cognitive function when sleep loss is unavoidable. Rather than relying on stimulants like caffeine or modafinil to push through fatigue, the team examines whether directly supporting the brain's phosphocreatine and ATP systems can maintain cellular energy and cognitive performance during acute sleep deprivation. The discussion looks at recent...
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Is Your Cellular Membrane Leaking the Fuel That Keeps You Going? (Why NAD+ Isn't Enough) | HOMe #022
Health Optimization Medicine Podcast
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Allen Bookatz, and Jodi Duval explore one of the most overlooked causes of declining cellular energy: the structural breakdown of the mitochondrial membrane. While many people invest in premium longevity supplements like NAD+, NMN, and CoQ10 to improve energy production, emerging research suggests these compounds cannot overcome a damaged mitochondrial membrane. The team explains how age-related phosphatidylcholine depletion weakens the mitochondrial lipid bilayer, causing proton leakage,...
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Dr. Dominic D'Agostino Explains What Ketones Actually Do to Your Body | HOMe Podcast #021
Health Optimization Medicine Podcast
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr sits down with Dr. Dominic D'Agostino, the premier researcher in ketogenic metabolic therapies. Moving past the mainstream fads of keto ice cream and internet trends, they break down how exogenous ketones actually impact cellular energy, cardiovascular health, and environmental stress. From the liver toxicity associated with certain high-dose ketone esters to the hidden vasodilatory superpowers of L-BHB, this discussion separates the biohacking hype from the physiological reality of ketone supplementation. Join us as...
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Metformin is Poisoning Your Cells | HOMe Podcast #020
Health Optimization Medicine Podcast
In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, Jodi Duval, and Dr. Jup Kuipers take a deep dive into the shocking new 21-year pre-diabetes follow-up study (DPPOS) published in the Journal of the American Medical Association on June 15, 2026. Moving past the mainstream longevity hype surrounding Metformin as an anti-aging cure-all, the faculty breaks down why chemically poisoning your enzymes is a profound mismatch for healthy, active individuals. From the bioenergetics of exercise to the clinical application of precision...
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The Gut-Brain-Microbiome Axis: Understanding Depression, Serotonin, & Probiotics | HOMe Podcast #019
Health Optimization Medicine Podcast
In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, Dr. Jup Kuipers, and Jodi Duval take a deep dive into the gut-brain-microbiota axis. Moving past the simplistic, pathogenic "pill-for-an-ill" approach of conventional psychiatry and the mainstream hype around over-the-counter probiotics, the faculty breaks down why establishing enteric safety must always precede biochemical optimization. Join us as we delve into: The Tripartite Axis: How the enteric microbiota, gut barrier, and central nervous system communicate at a molecular...
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Why You Can’t Out-Supplement a Dysregulated Nervous System | HOMe Podcast #018
Health Optimization Medicine Podcast
In this episode of the Health Optimization Medicine Podcast, Dr. Allen Bookatz, Dr. Ted Achacoso, and Jodi Duval tackle the widespread trend of supplement fatigue. As biohacking becomes a mindset of treating symptoms with heavy stimulants and endless pills, the faculty breaks down why forcing adaptation on an exhausted system only drives the body deeper into a chronic state of inflammatory defense. From the biophysics of the Cell Danger Response (CDR1) to practical parasympathetic upregulation, this roundtable shifts the focus from treating disease to establishing true autonomic safety. Join...
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Cellular Safety and the Dangers of Mechanical Blood Microplastic Detox | HOMe Podcast #017
Health Optimization Medicine Podcast
In this episode of the Health Optimization Medicine Podcast, our faculty, Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, Dr. Allen Bookatz, and Jodi Duval, tackle the recent trend of therapeutic plasma exchange and "blood washing". Moving past the mainstream marketing of plasmapheresis as a longevity cure-all, the team breaks down why mechanical filtering is only a surface-level fix for microplastic toxicity. From the autonomic anxiety caused by biological lockdown to the clinical application of precision metabolomics, this roundtable shifts the conversation from invasive procedures to...
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The HRV Paradox: Why Tracking Your Sleep Makes It Worse | HOMe Podcast #016
Health Optimization Medicine Podcast
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe faculty (Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, and Jodi Duval) tackles one of the most paradoxical trends in modern biohacking: sleep tracking. Moving past the mainstream obsession with daily device scores, the team breaks down the biochemical realities of how tracking your HRV might actually be sabotaging your sleep architecture. From the autonomic anxiety caused by digital wearables to the clinical application of precision chronobiology, this roundtable shifts the conversation from algorithmic scores to...
info_outlineIn this episode of the Smarter Not Harder Podcast, Dr. Elizabeth Yurth and Dr. Abid Husain join Dr. Scott Sherr to discuss why conventional medicine often overlooks the critical links between joint integrity, cardiovascular screening, and long-term healthspan. Together, they explore collaborative clinical communities, data-driven diagnostic strategies, and rethinking what really causes degeneration—and how to stop it.
Join us as we delve into:
• How a growing group of longevity-minded clinicians is changing the standard of care
• The truth about the RICE protocol and why it's outdated
• What most doctors miss about early cardiovascular disease detection
• Why inflammation—not wear and tear—is the true root of joint degeneration
This episode is for you if:
• You're a health professional looking to integrate regenerative insights
• You’re curious about the science behind injury progression and prevention
• You want to understand how imaging and biomarkers predict cardiac risk
• You’re interested in real-world health optimization, not just theory
You can also find this episode on…
YouTube: https://youtu.be/XE55hdSjNeM
Find more from Dr. Elizabeth Yurth:
Website: https://boulderlongevity.com/about/dr-elizabeth-yurth
Instagram: https://www.instagram.com/dryurth/
Find more from Dr. Abid Husain:
LinkedIn: https://www.linkedin.com/in/abid-husain-md-facc-abaarm-00874419/
Instagram: https://www.instagram.com/dr_abidhusain/
Find more from Smarter Not Harder:
Website: https://www.troscriptions.com/pages/podcast
Instagram: https://www.instagram.com/troscriptions
HOMeHOPe Symposium: https://homehope.org/homehope-symposium
Get 10% Off your purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org
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