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What Most Gut Protocols Get Wrong | SNH Podcast #148

Health Optimization Medicine Podcast

Release Date: 11/05/2025

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Health Optimization Medicine Podcast

In this episode of the HOMe Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz explore a foundational principle of Health Optimization Medicine: What’s toxic to the cell is toxic to every organ. Through real clinical cases — including mercury toxicity, arsenic exposure, and environmental toxin accumulation — the team reveals how modern medicine often misses the root cause of disease by focusing on isolated organ systems instead of cellular function. From chronic low-level toxin exposure to acute breakdown events, this episode highlights how toxins disrupt...

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In this episode of the Health Optimization Medicine Podcast, Boomer Anderson, Dr. Ted Achacoso, Dr. Scott Sherr, and Jodi Duval explore mental health through the lens of health optimization medicine. Rather than viewing mental health as a set of diagnoses, the conversation reframes it as a function of cellular health — where brain function is driven by mitochondrial performance, inflammation, nutrient status, and environmental inputs. From neurotransmitter imbalances to brain inflammation and the gut-brain-microbiome axis, this episode breaks down how modern stressors, lifestyle, and...

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In this episode of the Health Optimization Medicine Podcast, join Boomer Anderson, Dr. Ted Achacoso, and Jodi Duval as they break down one of the most important frameworks in Health Optimization Medicine — the Cell Danger Response (CDR). Originally developed by Dr. Robert Naviaux, the Cell Danger Response explains how cells respond to threat, adapt for survival, and either resolve or become “stuck” — leading to chronic disease. This episode walks through the three stages of the CDR, how mitochondria act as both sensors and signaling hubs, and why many modern conditions — from...

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In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr is joined by renowned neurologist and bestselling author Dr. David Perlmutter to explore one of the most important breakthroughs in brain health — the role of microglia. Often overlooked, microglial cells are the brain’s immune system and play a central role in determining whether the brain thrives or degenerates over time. Dr. Perlmutter explains how these cells can shift between protective (M2) and destructive (M1) states — and how this shift underlies neurodegenerative diseases like Alzheimer’s,...

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In this episode of the Health Optimization Medicine Podcast, join Boomer Anderson, Dr. Ted Achacoso, Dr. Allen Bookatz, and Jodi Duval as they explore chronobiology — and how modern life is disrupting the body’s natural rhythms. From jet lag and shift work to late-night scrolling and irregular meals, the conversation dives into what Dr. Ted calls “circadian pollution” — the mismatch between our biology and the environments we’ve created. More importantly, the team breaks down simple, powerful tools to re-entrain your body clock using light, food timing, and movement — all...

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In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe Faculty comes together for a roundtable conversation exploring the core philosophical framework behind Health Optimization Medicine. Dr. Scott Sherr, Boomer Anderson, and Dr. Allen Bookatz break down the three fundamental perspective shifts that redefine how we think about health, disease, aging, and the human body itself. Rather than focusing on disease management, this episode introduces the foundational principles behind building health from the cellular level up. Join us as we delve into: • The shift from...

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More Episodes

In this episode of the Smarter Not Harder Podcast, Boomer Anderson, Dr. Scott Sherr, Dr. Ted Achacoso, Jodi Duval, and Dr. Allen Bookatz come together for a powerful HOMeHOPe Faculty roundtable exploring the gut — not just as a digestive organ, but as the root of mood, metabolism, immunity, and long-term vitality. This conversation blends systems biology, ancient medicine, and cutting-edge diagnostics to give you a radically holistic view of gut health and what it really takes to heal from within.

Join us as we delve into:
• How gut health influences brain function, mood, and clarity
• The role of trauma and stress in gut dysfunction
• Stool testing, diagnostics, and when “more data” isn’t better
• Probiotics, fiber, and the personalized approach to microbiome support

This episode is for you if:
• You’re chasing mental clarity or performance through your gut
• You’ve tried “gut protocols” but still feel off
• You want a clinical, systems-based approach to GI health
• You’re ready to go beyond buzzwords and into the real science of the microbiome

You can also find this episode on…
YouTube: https://youtu.be/G4BHp6d9T00

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