Advances in Neuroregeneration: Biomimetic Scaffolds, Hydrogels, and Biomaterials for Optic, Facial, Spinal, and Peripheral Nerve Repair
Release Date: 11/14/2024
CNS Neurons That Actually Regenerate Throughout Life
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Dr. Reggie Edgerton - Neuromodulation for Spinal Cord Injury, Cerebral Palsy, Parkinsons, and more
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The Latest in Neural Regeneration Research and News
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In this heartfelt and inspiring inaugural episode, host Jarod Carter shares the deeply personal story behind the creation of The Neuron Regeneration Podcast and the Neuron Regeneration community. As the father of twins diagnosed with Spinal Muscular Atrophy (SMA), Jarod opens up about the challenges his family has faced and the ongoing fight to reverse the devastating effects of neurodegenerative diseases. He explains his mission to accelerate breakthroughs in neuron regeneration and the hope of finding treatments that can fully heal and repair damaged neurons—work that could impact millions...
info_outlineWelcome to another News and Abstract Reading episode of The Neuron Regeneration Podcast, aimed at providing listeners with a convenient way to stay up to date on the latest in neural regeneration research, innovations, and advancements.
Papers and Topics Discussed:
- Implantation of biomimetic polydopamine nanocomposite scaffold promotes optic nerve regeneration through modulating inhibitory microenvironment
Published in the Journal of Nanobiotechnology, this study presents a biomimetic GA@PDA scaffold designed to promote optic nerve regeneration by reducing oxidative stress and modulating inflammation. Tested in a rat model, the scaffold enhanced retinal ganglion cell survival and axonal regeneration, suggesting potential applications for optic nerve injuries and possibly other neuroinflammatory conditions like stroke. - The Effect of Rosuvastatin on Facial Nerve Regeneration After Facial Nerve Injury: An Experimental Animal Study
Published in the American Journal of Otolaryngology, this study examines rosuvastatin’s role in enhancing facial nerve recovery in rats with traumatic paralysis. Combined with methylprednisolone, rosuvastatin significantly improved nerve function and structure, suggesting its potential for treating facial nerve injuries.
- Clickable immune-microenvironment modulated hydrogels for spinal cord injury repair
Published in Journal of Colloid and Interface Science, this study presents MP-enriched injectable hydrogels that promote nerve regeneration and functional recovery in spinal cord injuries by modulating the immune-inflammatory environment. These findings highlight the hydrogels’ potential for SCI repair and other neuroinflammatory conditions.
- Olfactory receptors in neural regeneration in the central nervous system
Published in Neural Regeneration Research, this review explores olfactory receptors as potential targets for enhancing neural regeneration in the central nervous system. Insights from olfactory neuron regeneration suggest new therapeutic approaches for CNS injuries, including spinal cord injury and Alzheimer’s disease.
- Alginate Use in Orthopedics and Peripheral Nerve Repair: A Systematic Review
Published in Cureus, this review examines alginate's applications in orthopedics and peripheral nerve repair. The findings suggest that alginate supports Schwann cell migration and reduces scar tissue, potentially aiding nerve regeneration and offering promise for orthopedic and nerve repair therapies.
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