Ep 39: The Urine Test That Could Replace Invasive Cancer Biopsies
Release Date: 08/26/2025
Ep 42: MedTechs's 10X Advantage - How Real-World Data Expands Device Impact
Boombostic Health
Summary Pre-market clinical trials are essential — but they don’t reflect how devices truly perform once they’re in the real world. In this episode of Boombostic Health, host Bradley Bostic sits down with Dr. Amelia Hufford, Co-Founder and SVP of Clinical and Regulatory Science at 3Aware, to unpack why real-world data (RWD) is critical to the survival of medical devices — and why mindset, not science, may be the biggest barrier holding MedTech back. Amelia shares her 20+ year journey in scientific and clinical research, including a decade in MedTech leading regulatory and clinical...
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Ep 41: From 18% to 80%: The Pregnancy Risk America Ignores
Boombostic Health
Why is giving birth in the United States still so risky—especially for Black and Native American mothers? In this powerful episode of Boombostic Health, host Bradley Bostic sits down with Tiffany Hall, a nurse and maternal health expert who has spent decades on the frontlines of patient care and blood management. Tiffany exposes the hidden pregnancy risk no one is talking about: anemia. Drawing from both clinical experience and hc1’s MyBloodHealth technology, Tiffany explains how anemia silently drives up rates of hemorrhage, heart complications, postpartum depression, and even...
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Ep 40: How AI Is Quietly Building Healthcare’s Next Multi-Billion Companies
Boombostic Health
AI in healthcare isn’t about robot doctors — it’s about building billion-dollar businesses. In this episode of Boombostic Health, Bradley Bostic sits down with Nigel Ohrenstein, CEO of Diagnostic Robotics and veteran healthcare entrepreneur, to explore how agentic AI is quietly reshaping the $4T healthcare industry. Nigel has taken companies from napkin sketch to multi-billion-dollar scale — most notably co-founding Lumeris and now leading Diagnostic Robotics. He shares what it really takes to scale in healthcare, why execution matters more than ideas, and how AI is transforming the...
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Ep 39: The Urine Test That Could Replace Invasive Cancer Biopsies
Boombostic Health
96% Accurate Cancer Detection — Without an Invasive Biopsy? The Breakthrough Test That Could Save Millions What if detecting cancer was as simple as giving a urine sample? No needles. No surgery. No fear. In this episode of Boombostic Health, host Bradley Bostic sits down with Curtiss McNair Jr., VP of Operations at PanGIA Biotech, to unpack one of the most groundbreaking medical innovations in decades: a urine test powered by AI that can detect multiple cancers with jaw-dropping accuracy. But this conversation isn’t just about the science. It’s also about the leadership and vision...
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Ep 38: From Lawyer to $18 5B Healthcare Deal — How Lee Shapiro Made the Leap
Boombostic Health
What does it really take to build and scale a healthcare company? In this episode of Boombostic Health, Bradley Bostic sits down with Lee Shapiro—Managing Partner at 7wire Ventures, former President of Allscripts, and co-founder of Livongo—to talk about his journey from “recovering lawyer” to building one of the most successful companies in digital health. Lee shares how he and Glenn Tullman grew Livongo into a public company and ultimately merged with Teladoc in a landmark $18.5 billion deal. He breaks down why healthcare innovation is never an overnight success, how to spot “Uber...
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Ep 37: Predicting Menopause: How Life Ahead Is Transforming Women’s Health with Science & Data
Boombostic Health
Episode Description What if women could know — years in advance — when perimenopause and menopause will begin? In this episode of Boombostic Health, host Bradley Bostic talks with Nich Gentry and Dr. Lizellen La Follette of Life Ahead, a groundbreaking company combining ultrasound, personalized data, and validated science to give women a clear picture of their reproductive timeline. You’ll learn: Why ovarian aging is the “canary in the coal mine” for overall health. How early menopause prediction could transform bone health, cognitive health, and preventive care. The science...
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Ep 36: Why Hospitals Are Selling Profitable Labs to Survive
Boombostic Health
Summary Guest: Melissa Butterworth, CEO of Advanced Strategic Partners Overview: Hospitals are under extreme financial pressure—but what if the answer to their budget woes is sitting right inside their own labs? In this eye-opening episode, Melissa Butterworth—who’s led over $2.4 billion in lab transactions—joins Bradley to explore the growing trend of health systems divesting lab assets. Together, they unpack: Why hospitals are selling even profitable lab outreach operations How to accurately assess the real value of a lab business What happens post-sale—and how to unlock...
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Ep 35: The 53% Failure Rate in Medicine—and How AI Can Fix It
Boombostic Health
In this episode, host Bradley Bostic sits down with healthcare innovator and author Jim Wallace to discuss how AI, wearables, genomics, and big data are transforming the way care is delivered. Wallace shares insights from his new book, Precision Medicine, AI, and the Science of Personalized Health Care, revealing why traditional models of care are falling short—and what’s next. What you’ll learn: Why 53% of medications don’t work as intended How social support increases patient survival by up to 50% Where healthcare investment is missing the mark What the Alice Walton School of...
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Ep 34: From Fax to Fast: The Fight for Real Healthcare Interoperability
Boombostic Health
In this episode of Boombostic Health, host Bradley Bostic speaks with Greg Stein, CEO of Shadowbox, about the challenges and innovations surrounding electronic health records (EHRs) and lab test ordering. They discuss the limitations of traditional EHR systems, the innovative solutions Shadowbox provides to streamline lab test ordering, and the broader implications for diagnostics and patient care. The conversation also touches on community health initiatives, the importance of interoperability in healthcare, and the potential for partnerships to enhance healthcare delivery. Takeaways ...
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Ep 33: From Paralysis to Progress: 5 Stories Reshaping Healthcare
Boombostic Health
Episode Summary: In this special “Best Of” episode, we bring together the boldest, most unforgettable moments from our five most-watched interviews on Boombostic Health. These leaders aren’t just talking about change—they’re making it happen. In just 30 minutes, you'll hear from entrepreneurs, investors, clinicians, and health system leaders who are all challenging the business of healthcare in radically different—and deeply personal—ways. Featured Guests: Chris Leeuw – After surviving a paralyzing spinal cord injury, Chris defied the odds, relearned to walk, and launched...
info_outline96% Accurate Cancer Detection — Without an Invasive Biopsy? The Breakthrough Test That Could Save Millions
What if detecting cancer was as simple as giving a urine sample? No needles. No surgery. No fear.
In this episode of Boombostic Health, host Bradley Bostic sits down with Curtiss McNair Jr., VP of Operations at PanGIA Biotech, to unpack one of the most groundbreaking medical innovations in decades: a urine test powered by AI that can detect multiple cancers with jaw-dropping accuracy.
But this conversation isn’t just about the science. It’s also about the leadership and vision needed to take innovations like this from the lab to real-world patients.
🔑 Key Takeaways
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The Breakthrough: How PanGIA’s urine test achieves 96% sensitivity, 74% precision, and an 84% F1 score in early cancer detection.
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Why It Matters: 2 out of 3 biopsies for prostate and brain cancer come back benign. This test could eliminate unnecessary, invasive procedures.
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Global Impact: Why PanGIA launched first in India, and how cultural barriers to invasive exams are driving adoption.
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AI in Action: How artificial intelligence identifies subtle biomarker patterns invisible to the human eye.
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The Leadership Gap: Why building better healthcare depends not just on new technology, but on bold leaders willing to drive systemic change.
🌍 Why You Should Listen
Cancer has touched nearly every family, and early detection is the single most powerful tool we have to save lives. This episode blends cutting-edge science, practical healthcare realities, and leadership wisdom that every innovator, clinician, and patient advocate needs to hear.