EP19 Personalized Medicine: Why Healthcare Needs a Check Engine Light - Dr. Ali Tinazli (lifespin)
Beyond the Blueprint - Health Series
Release Date: 05/19/2025
Beyond the Blueprint - Health Series
What happens beyond the digital front door? In this AMDIS collaboration, Dr. Yaa Kumah-Crystal, Dr. Natalie Pageler, and Dr. Sarah Rush unpack the complex realities of digital family engagement in pediatric care. From patient portals and teen privacy laws to ambient documentation and AI-enabled translation, this panel explores how hospitals can rebuild trust, reduce barriers, and design systems that truly work for families. Together, they examine cultural readiness, access equity, and why health systems must treat family engagement as both a design challenge and a clinical imperative. Key...
info_outlineBeyond the Blueprint - Health Series
In this episode we explore why so many AI initiatives in healthcare stall—and how nursing leaders can change that. Dr. Jing Wang (FSU Nursing), Athena Fernandez (Penn Medicine), and Troy Seagondollar (formerly Kaiser Permanente) reflect on the current AI landscape and what it takes to make tools truly work for nurses at the bedside. From sepsis prediction models to staffing automation, they share hard-won lessons in AI governance, change management, and clinical trust. Our panel dives into the growing gap between innovation and implementation—and how nurse-led strategies can help...
info_outlineBeyond the Blueprint - Health Series
Join us for a conversation with healthcare communications veteran John Elms as he breaks down what it really takes to design digital systems that frontline clinicians will actually use. Drawing on decades of leadership at TigerConnect, Critical Alert, and Spectralink, Elms shares hard-won lessons on user-centered design, project governance, and the hidden costs of fragmented communication tools. We explore a real-world case study that improved patient transport efficiency by 55%, and dive into strategies for aligning IT, operations, and clinical teams around change that sticks. Whether you're...
info_outlineBeyond the Blueprint - Health Series
Join hosts Keith Washington and Kris Baird for a conversation with Michelle Lingner, FNP-C, RN-BSN, RNFA—a trauma nurse practitioner at ECU Health who's redefining what it means to lead without formal authority. Michelle shares how intentional mindset shifts transformed her from burned out to energized, and how that shift rippled through her entire team. Drawing on her experience in a 1,000-bed Level 1 trauma center, she reveals practical strategies for peer-to-peer influence, closing communication gaps that delay patient care, and choosing positivity even in high-pressure environments. Kris...
info_outlineBeyond the Blueprint - Health Series
Join us for a conversation with nurse executive and healthtech innovator Patrick Baker shares the story behind Palarum’s smart sock—an advanced wearable that’s dramatically reducing patient falls without adding to clinical workload. With insights shaped by decades on the frontlines, Baker walks us through how alarm fatigue, design thinking, and data transparency inspired a smarter approach to patient safety. We explore how real-time mobility tracking, clinical workflow integration, and human-centered innovation are shifting the paradigm in hospital care. Whether you're in nursing...
info_outlineBeyond the Blueprint - Health Series
In this episode of Beyond the Blueprint, emergency physician and health IT strategist Dr. John Lee unpacks the systemic failures slowing down our emergency departments—and why AI alone won’t fix them. With firsthand insights from the front lines and the boardroom, Dr. Lee makes the case for building data governance and transparency before jumping into artificial intelligence. We explore why foundational analytics matter, what most organizations get wrong about innovation, and how strategic design can reduce ED chaos. Whether you’re a CMIO, a health system leader, or innovating in...
info_outlineBeyond the Blueprint - Health Series
In this episode of Beyond the Blueprint, executive coach and former Harvard Health Services CIO Dr. Michael Brown explores the leadership journey of physicians in today’s complex health systems. Drawing on decades of experience in medicine, informatics, and organizational change, Dr. Brown shares how executive coaching can unlock potential, align values with action, and improve outcomes at scale. We unpack the mindset shifts required for physicians stepping into leadership, how to tailor coaching for impact, and why the best athletes—and leaders—never stop evolving. Whether you're a...
info_outlineBeyond the Blueprint - Health Series
In this episode of Beyond the Blueprint, physician and health IT expert Dr. Harm Scherpbier returns to challenge the status quo of single-vendor EHR ecosystems. Drawing on decades of experience across clinical practice, informatics, and executive leadership, Harm lays out a bold case for a modular IT approach—one that accelerates innovation, enhances clinician experience, and reduces cost. We dive into ambient clinical documentation, API-driven interoperability, and why "roadmap" should be every CIO’s red flag. Whether you're a CMIO, a digital health entrepreneur, or a hospital leader...
info_outlineBeyond the Blueprint - Health Series
In this episode of Beyond the Blueprint, we sit down with healthtech veteran John Elms to unpack the complexities of clinical communication and workflow orchestration. Drawing from decades of experience and a front-row seat to digital transformation, John explores why care team collaboration remains so fragmented—and what’s required to fix it. From HIPAA-induced workarounds and alert fatigue to EHR lock-ins and the lack of federated communication systems, we examine the real-world barriers to connected care. Along the way, we discuss alarm management, platform interoperability, and why...
info_outlineBeyond the Blueprint - Health Series
Join us for a candid retrospective on the Epic EHR, recorded in collaboration with AMDIS. In this episode, Dr. Yaa Kumah-Crystal, Dr. Roy Esaki, and Dr. John Lee share lessons learned from the frontlines of digital transformation, from navigating complex governance to managing integration debt and cloud migration risks. They explore why Epic rollouts often go off track, how to balance innovation with standardization, and where leadership must focus to support sustainable success. Our panelists unpack the realities of patient engagement, third-party tools, and cultural readiness—while...
info_outlineJoin us as we explore personalized medicine with Dr. Ali Tinazli, CEO of lifespin. In this episode, Dr. Tinazli discusses how metabolomics technology can create a comprehensive snapshot of a patient's health status using blood samples and advanced analytics. He explains how lifespin's innovative approach uses nuclear magnetic resonance and AI to detect early signs of disease through metabolic profiles, presenting results in an intuitive traffic light system. Dr. Tinazli shares insights on making healthcare more accessible and affordable, comparing the technology to a car's check engine light for human health. He also addresses the challenges of market adoption, privacy concerns, and integration with existing healthcare systems. Tune in to learn how this emerging technology could transform preventive care, empower patients with actionable health data, and potentially reduce healthcare costs through earlier intervention.
Key Takeaways
- Personalized medicine aims to provide a comprehensive health snapshot from a blood sample.
- Lifespin's General Metabolomic Profiler uses a traffic light system to indicate health status.
- Early disease detection is hindered by unspecific symptoms and traditional testing methods.
- Innovative technologies like AI and nuclear magnetic resonance can improve diagnostics.
- Personalized medicine is essential for managing non-communicable diseases and healthcare costs.
- Adoption of personalized medicine is still in early stages, with more traction in specialty diagnostics.
- Building credibility in the healthcare market is crucial for new technologies.
- Preventive care is a key focus for Lifespin's future developments.
- Corporate health programs present a lucrative opportunity for personalized medicine.
- Effective communication and education are vital for patient engagement in health management.
Episode Highlights
00:00 Introduction to Personalized Medicine
01:35 Meet Dr. Ali Tinazli
06:13 Challenges in Current Healthcare Diagnostics
09:52 lifespin Methodology vs. Traditional Techniques
12:34 Real-world Examples
15:39 Is this Technology Ready for Primetime?
17:23 Population Health and Personalized Medicine
20:43 Is the Tech Clinically and Financially Effective
21:09 Adoption and Market Penetration of lifespin
21:37 Next Steps for lifespin
23:58 If Chemistry is King, Physics is Queen
25:05 Future Directions and Market Strategies
32:26 Conclusion and Call to Action
Guest: Dr. Ali Tinazli, lifespin
Host: Gregg Malkary - Spyglass Consulting Group
Cohost: Keith Washington - Companions in Courage Foundation
Sponsored by: Simplifi Medical & Storage Systems Unlimited
Audio/Video: Tim Jones - Health Nuts Media
Marketing: Josh Troop - Troop-Creative
Learn More at: www.beyond-blueprint.com