Low SHBG: The Hidden Hormone Gatekeeper Sabotaging Your Weight & Energy
Rejuvenate Your Hormones and Wellness
Release Date: 07/01/2025
Does Testosterone Help with Parkinson's?
Rejuvenate Your Hormones and Wellness
What if the fatigue, brain fog, and low drive you or a loved one are experiencing with Parkinson’s isn’t just Parkinson’s? What if hormones, specifically testosterone, are playing a bigger role than most providers realize? I’m Colleen Kupka, owner of in Scottsdale, AZ. In this episode, I dive into a critical but often overlooked question: Can testosterone therapy improve the quality of life for men with Parkinson’s? Here’s what you’ll learn in this episode: Why most providers miss the hormone connection in Parkinson’s care The overlap between low testosterone...
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Is Low SHBG Sabotaging Your Hormones?
Rejuvenate Your Hormones and Wellness
Are you doing everything “right” — eating clean, working out, trying every skincare trick — yet still struggling with stubborn belly fat, unexplained fatigue, or adult acne that just won’t clear? The real problem could be an overlooked protein: Sex Hormone-Binding Globulin (SHBG). Hi, I’m Colleen Kupka, Nurse Practitioner and leading hormone specialist in Scottsdale, AZ, and founder of Rejuvenate Hormone and Weight Loss Center. Come along with me as I dive into SHBG — what I call your body’s “hormone gatekeeper.” Inside this episode, you’ll learn: What SHBG really...
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Low SHBG: The Hidden Hormone Gatekeeper Sabotaging Your Weight & Energy
Rejuvenate Your Hormones and Wellness
Are you doing everything “right” — eating clean, working out, trying every skincare trick — yet still struggling with stubborn belly fat, unexplained fatigue, or adult acne that just won’t clear? The real problem could be an overlooked protein: Sex Hormone-Binding Globulin (SHBG). Hi, I’m Colleen Kupka, Nurse Practitioner and leading hormone specialist in Scottsdale, AZ, and founder of Rejuvenate Hormone and Weight Loss Center. Come along with me as I demystify SHBG — what I call your body’s “hormone gatekeeper.” Inside this episode, you’ll learn: What SHBG really...
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Why Estradiol Isn’t Always the Answer in Perimenopause
Rejuvenate Your Hormones and Wellness
Hi, I’m Colleen Kupka, hormone specialist and founder of Rejuvenate Hormone and Weightloss Center in Scottsdale, Arizona. In this episode, I’m sharing a story I hear far too often: a woman in perimenopause, feeling overwhelmed, confused by her lab results, and convinced that estradiol is the fix. But when we’re in this phase, our hormones—especially estradiol—fluctuate dramatically, sometimes even doubling from one day to the next. Relying on lab numbers alone can actually lead to bigger problems, not solutions. Dive in with me as I explain: Why estradiol can be risky in...
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Does Estradiol Increase Stroke Risk? The Truth About Hormone Therapy Every Woman Needs to Know
Rejuvenate Your Hormones and Wellness
today or call me directly at 480-589-3999. Whether you’re local to Scottsdale or prefer a , I’m here to meet you wherever you are.
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The Empowered Woman’s Guide to Hormones & Wellness
Rejuvenate Your Hormones and Wellness
Perimenopause is one of the most misunderstood—and under-discussed—phases in a woman’s life. Many women come to me feeling confused, exhausted, and frustrated, unsure of what’s happening to their bodies or where to turn for answers. A recent clinical study confirms what I see every day: most physicians aren’t adequately preparing women for perimenopause or menopause, leaving them to navigate this major life shift alone. In this episode, I break down: What perimenopause actually is Common symptoms like brain fog, insomnia, mood swings, and low libido Why this phase can last up to 10...
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Insulin Resistance the BIG Miss about the Importance of Hormones Part 2
Rejuvenate Your Hormones and Wellness
Hormones and they Role they Play with Insulin Resistance Host: Colleen Power Kupka -FNP-C Location: Scottsdale, AZ Podcast: Rejuvenate Your Hormones and Wellness In this episode I discuss 1. Insulin Resistance 2. Let's talk about Hormones (Estradiol, Tesosterone, Thyroid, SHBG, Progesterone) 3. Common Supplements that may help with Insulin Resistance 4. Hyperthyroid or Hypothryoid may contribute to Insulin Resitance 5. Continour Glucose Monitor 6. Weight Loss Medications ...
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Insulin Resistance-The BIG Miss Part 1
Rejuvenate Your Hormones and Wellness
Insulin Resistance – The Big Miss (Part 1) In this episode, we explore the often-overlooked topic of insulin resistance, breaking down its causes, risks, and the lifestyle changes that can help manage or even reverse it. Here’s what you’ll learn: What is Insulin Resistance? An easy-to-understand explanation of how your body processes glucose and what happens when it doesn’t work as it should. Key Risk Factors: From belly fat to genetic predispositions, learn the signs and causes of insulin resistance. Diet Discussions: Keto Diet: Benefits and why it may not be a long-term solution....
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How Hormones May Impact Your Cholesterol and Cardiovascular Risks
Rejuvenate Your Hormones and Wellness
How Hormones May Impact Your Cholesterol and Cardiovascular Risks Host: Colleen Power Kupka -FNP-C Location: Scottsdale, AZ Podcast: Rejuvenate Your Hormones and Wellness In this episode, we discuss: 1) Heart Disease Stats 2) Total Cholesterol, LDL, HDL 3) Measuring APO B may make a difference 4) Hormones how they may decrease your cholesterol levels 5) Lifestyle Change About Colleen Colleen has advanced certification in the area of bioidentical hormone replacement therapy. She received her training at Worldlink Medical from a pioneer in the BHRT field, Dr. Neal Rouzier....
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Testosterone and Estradiol Defiency in Men
Rejuvenate Your Hormones and Wellness
Testosterone and Estradiol Defiency in Men Host: Colleen Power Kupka -FNP-C Location: Rejuvenate Hormone and Weight Loss Center, Scottsdale, AZ Podcast: Rejuvenate Your Hormones and Wellness In this episode, we discuss 1. Hypogandism 2. Symptoms of Low Testosterone 3. Labs 4. What should my testosterone levels be? 5. The difference forms of Testosterone 6. Why Estradiol is important 7. Symptoms of Low Estradiol 8. What should my Estradiol...
info_outlineAre you doing everything “right” — eating clean, working out, trying every skincare trick — yet still struggling with stubborn belly fat, unexplained fatigue, or adult acne that just won’t clear?
The real problem could be an overlooked protein: Sex Hormone-Binding Globulin (SHBG).
Hi, I’m Colleen Kupka, Nurse Practitioner and leading hormone specialist in Scottsdale, AZ, and founder of Rejuvenate Hormone and Weight Loss Center. Come along with me as I demystify SHBG — what I call your body’s “hormone gatekeeper.”
Inside this episode, you’ll learn:
- What SHBG really does and why it’s so crucial for your sex hormones, energy, and mood
- How insulin resistance, metabolic syndrome, and even poor sleep can tank your SHBG levels — and what that means for your long-term health
- The subtle signs your SHBG may be too low, including skin tags, midsection weight gain that won’t budge, unwanted facial hair, or thinning scalp hair
- The exact labs I run for my patients — because a basic thyroid panel just isn’t enough
- My step-by-step plan to naturally support healthy SHBG levels through a nutrient-dense diet, effective stress management, aerobic & strength training, and advanced options like tirzepatide, which research shows can outperform Ozempic for weight loss and metabolic health
If you’ve ever felt dismissed by “normal” labs or generic advice, you deserve answers, and I am here to help you find them. Call me at (480) 589-3999 or book your complimentary hormone consultation with me today. Let’s make sure your SHBG — and your entire hormone system — is working for you, not against you.
Serving Scottsdale, Phoenix, and patients nationwide seeking evidence-based hormone therapy, weight loss, and metabolic optimization.
Why I know you'll love this episode:
You’ll leave feeling informed, empowered, and ready to take action — so you can finally stop guessing and start feeling like you again.
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