Histamine & Burnout: The Connection with Will Cole
The Girlfriend Doctor w/ Dr. Anna Cabeca
Release Date: 01/31/2025
The Girlfriend Doctor w/ Dr. Anna Cabeca
Hormones can be wild, especially in perimenopause and menopause, and sometimes it feels like no one talks about just how much they mess with your mind, mood, and energy. But there’s a real science behind why things feel off, and it’s not all in your head. I sat down with my friend and hormone expert, Dr. Betty Murray, to talk about the gut-brain-hormone connection and why it’s such a big deal for women in this season of life. She’s not only a Functional Medicine Pioneer with over 20 years of experience, she’s also the Founder of The Menrva Project, a game-changing platform rethinking...
info_outlineThe Girlfriend Doctor w/ Dr. Anna Cabeca
You might not think of light as a healing tool, but red and near-infrared light can do some pretty amazing things, especially when it comes to pelvic health. From easing perimenopause struggles to helping your body bounce back after birth, this kind of light therapy is opening up a whole new world for women dealing with pain, discomfort, or intimacy issues. I had such a good conversation with Dr. Genevieve Newton (Fringe’s Scientific Director) and Elizabeth Frey (Pelvic Health Physiotherapist) about how this all works, and why more women need to know about it. If you’ve been dealing with...
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Hormones are wild, especially when you realize they’re not just about how much you have, but how your body uses and processes them behind the scenes. That’s what hormone metabolite testing helps uncover, and honestly, it’s a game-changer. I’m sitting down with Dr. Liz Bartman, an incredible Naturopathic Doctor with a deep background in hormone science, to talk about how we can actually test our hormones in a meaningful way and what those results are really telling us. We chat about the different ways to test—blood, saliva, urine—and why each one tells a slightly different story....
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Bladder leaks, dryness, and low libido aren’t exactly dinner table topics… but maybe they should be. These issues are way more common than we think, especially during and after menopause, and they have a huge impact on how we feel day to day. That’s why I sit down with Dr. Rena Malik, a Board-Certified Urologist and Sexual Medicine Specialist who’s made it her mission to talk about the things most people won’t. We talk about everything from pelvic floor problems to how hormones like estrogen and testosterone affect our sexual health and bladder function. Dr. Rena shares why stress...
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Hormonal shifts in perimenopause and menopause can do more than throw off your cycle—they can actually stir up inflammation, spark strange symptoms, and even trigger immune responses that leave you wondering, what is going on with my body? If you've ever felt like your symptoms don’t quite “fit in a box,” this conversation is for you. I sit down with Dr. Tania Dempsey—a brilliant MD and expert in complex, multi-system diseases—to talk about Mast Cell Activation Syndrome (MCAS), why it’s often missed in women, and how hormones can play a huge role in triggering it. This episode...
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Growing up with a mom struggling with severe mental illness, Karena Dawn learned early what it meant to carry heavy things in silence. That experience shaped so much of her life—including the dark years she rarely talked about. In this episode, she shares her journey from that painful silence to healing, forgiveness, and ultimately, purpose. We talk about how fitness became her lifeline and how she found her voice by telling the truth in her powerful memoir, The Big Silence. You may know Karena as the co-founder of Tone It Up, a wellness community that’s inspired millions of women—but...
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We’re back for part two of an eye-opening, soul-stirring conversation with Seren Bertrand. We’re talking sacred sexuality, feminine energy, and that beautiful, mystical power that lives in your body, especially in your vulva. Seren shares her own story of reclaiming her sensual energy and reminds us why our bodies are not only wise, but sacred. If you’ve ever felt disconnected or just a little curious about what it means to feel truly alive and sensual in your skin again, you’re in the right place. Seren is the brilliant Author of Womb Awakening and a guiding voice in the feminine...
info_outlineThe Girlfriend Doctor w/ Dr. Anna Cabeca
Menopause can feel like everything’s shifting—your body, your emotions, even your sense of who you are. It’s not just a phase to get through, it’s an invitation to slow down, listen in, and reconnect with the deeper wisdom within. In this conversation with Seren Bertrand, the award-winning Author of Womb Awakening, we talk about what it really means to step into this next chapter as a woman. Seren has walked with thousands of women through their feminine awakening and brings such grounded, mystical wisdom to the table. We talk about the “Dark Goddess” showing up at age 28, the...
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Most women don’t realize just how much menopause messes with their pelvic floor—until they’re leaking when they laugh or feeling like their body just isn’t working the way it used to. These changes can feel confusing, isolating, and even a little embarrassing—but they’re more common (and more fixable) than you think. This week, I sat down with my friend Kim Vopni—aka The Vagina Coach—to talk about what’s really going on with your body during this phase of life. Kim’s a certified personal trainer, menopause support practitioner, CEO of a Global Pelvic Health company, and...
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Most of us don’t think much about our pelvic floor—until we start leaking when we laugh or feel pain we can’t explain. That’s why I had such a powerful conversation with my friend Jana Danielson, who knows this topic inside and out. She shared how her own journey through chronic pelvic pain led her to discover the healing power of breath, movement, and mindset. Jana’s not just a wellness expert—she’s a woman who turned her pain into purpose. From teaching Pilates to creating the world’s first pelvic floor fitness tool (yes, the Cooch Ball is a thing—and it works), she’s...
info_outlineWhat’s really behind your fatigue and brain fog? Ever feel like your body’s sending you an SOS, but you’re not sure what it’s trying to say? I sit down with Dr. Will Cole, a leading Functional Medicine Expert, to chat about two health issues that often fly under the radar: histamine intolerance and burnout. We talk about how these sneaky culprits can mess with your energy, focus, and even your digestion—especially during midlife or perimenopause. If you’ve been feeling “off” and can’t quite put your finger on why, this is a conversation you don’t want to miss.
Dr. Will doesn’t just share the science—he gives some seriously practical tips to help you feel better. We get into why gut health is such a big deal for managing histamine levels and what to do if you’re feeling stuck in a cycle of exhaustion. Burnout is also part of our conversation, and you’ll be surprised at how it’s not always tied to laziness—but it’s your body’s way of waving a red flag. Dr. Will shares simple, doable strategies like breathwork and mindfulness to help you reset and feel like yourself again.
And by the way, if you’re struggling with low energy, low libido, hormone imbalances, or menopausal symptoms, you’ve got to try my Mighty Maca Plus! My clients have called it a “godsend”. Head over to dranna.com/drinkmaca to give it a try—and experience the difference!
Key Timestamps:
[00:00:00] Introduction.
[00:01:44] Histamine intolerance in midlife.
[00:04:57] Histamine intolerance and hormones.
[00:07:29] Histamine intolerance symptoms and causes.
[00:11:28] Histamine intolerance management strategies.
[00:16:50] Burnout versus laziness.
[00:19:17] Nervous system dysregulation explained.
[00:21:56] Vagal tone stimulation practices.
[00:27:30] What breathwork is best to practice?
[00:29:58] Cold plunging for those with histamine intolerance.
Memorable Quotes:
"Not to say that perimenopause is causing histamine intolerance, but it can be certainly be gasoline on the fire for an already tempestuous immune system." [00:06:29] – Dr. Will Cole
"The right type of breathwork or the right type of medication for you is the one that you can stay consistent with that is conducive and congruent to your healing." [00:27:58] – Dr. Will Cole
Links Mentioned:
Keto Green Shake: https://dranna.com/drinkmaca
Connect with Dr. Will Cole:
Website: https://drwillcole.com/
Instagram: https://www.instagram.com/drwillcole
Podcast: https://drwillcole.com/podcast
Connect with Dr. Anna Cabeca:
Website: https://drannacabeca.com/pages/show
Instagram: https://www.instagram.com/thegirlfrienddoctor/
YouTube: https://www.youtube.com/@thegirlfrienddoctor
TikTok: https://www.tiktok.com/@drannacabeca
Produced by Evolved Podcasting: www.evolvedpodcasting.com