The link between epigenetics and disease | Fab Mancini
The Girlfriend Doctor w/ Dr. Anna Cabeca
Release Date: 03/12/2026
The Girlfriend Doctor w/ Dr. Anna Cabeca
You finally get the appointment. You tell your doctor you're not sleeping, the weight is climbing, and your moods feel like someone else's. You walk out with a prescription for an antidepressant, or with nothing at all. Dr. Deborah Kwolek, assistant professor of medicine at Harvard Medical School and director of Harvard's Women's Health and Menopause course, joins me to talk about why so many doctors were never taught menopause care and what she's doing to change it. We cover the exact questions to bring to your next appointment, your estrogen by the numbers, the labs to know, who may need to...
info_outlineThe Girlfriend Doctor w/ Dr. Anna Cabeca
Your brain has its own immune cells, and the way you live each day helps decide whether they protect you or turn on you. Two-thirds of Americans living with Alzheimer's are women. Living longer doesn't explain that gap, girlfriend. So what does? I'm so happy to welcome back my dear friend Dr. David Perlmutter, board-certified neurologist and author of the New York Times bestseller Brain Defenders. He explains microglia, the immune cells that make up about 10% of your brain. On a good day, they're like firefighters in the firehouse, quietly repairing the blood-brain barrier and helping your...
info_outlineThe Girlfriend Doctor w/ Dr. Anna Cabeca
A divorce. A layoff. A season where you held everything together for everyone. Your body flipped into fight or flight to protect you, exactly the way it was built to. But what happens when the stress passes and your nervous system never gets the message? Bioenergetic medicine expert Dr. Sue Morter, author of The Energy Codes and The Anatomy of Awakening, explains the hidden stress your body can keep carrying for years. She shows how that old emergency ripples through your adrenals, your thyroid, and your hormones in midlife. Then she walks me through her first two steps. The wise belly breath,...
info_outlineThe Girlfriend Doctor w/ Dr. Anna Cabeca
When a woman sits across from Dr. Anna after a breast cancer diagnosis, she asks one question. What did your oncologist say caused it? Almost every time, the answer is a blank stare. Dr. Nasha Winters has lived that silence from the inside. By 19, she had collected a decade of diagnoses, including PCOS, endometriosis, IBS, anxiety, and thyroid trouble. Then she landed in the ER with a grapefruit-sized tumor and was told she was too ill for treatment. In this conversation, she shares the three things she credits with changing her path. She also explains how childhood trauma can shape the immune...
info_outlineThe Girlfriend Doctor w/ Dr. Anna Cabeca
Tell me if you've heard this before. You're sleeping. You're eating the way you were told to eat. Your labs come back normal, and you still know something is off. That's the woman I had in mind for this conversation. After twenty years in hormone and longevity medicine, here's what I keep coming back to. Most of what supports your hormones comes down to the foundations, like light, darkness, and when you eat, and so many of them cost you nothing. My guest, Sarah Kleiner, is board-certified through the Quantum Biology Institute and the creator of My Circadian App. She came to this work the hard...
info_outlineThe Girlfriend Doctor w/ Dr. Anna Cabeca
Dr. Anna sits down with triple board-certified dermatologist, internist, and dermatopathologist Dr. Mamina Turegano for a deep dive into skin health from the inside out. They cover the real drivers of collagen breakdown, which anti-aging ingredients and procedures actually hold up to decades of evidence, and how to build a sunscreen routine you don't have to second-guess. The conversation then turns to two of the toughest conditions in women's health, rosacea and vulvar lichen sclerosus, with practical, root-cause-informed guidance for both. This is the episode to bookmark if you've ever...
info_outlineThe Girlfriend Doctor w/ Dr. Anna Cabeca
I was sitting in my studio in Dallas with four women who had just spent five months inside my Magic Menopause Certification, and every one of them got emotional before we even started recording. That tells you something about what this season of life actually does to a woman who thought she had it handled. As a triple board-certified OB/GYN and the creator of the Keto-Green method and the Magic Menopause Coach Certification, I sat down with graduating coaches Chelsea, Song, Tara, and Jamie for a live, unscripted panel on everything nobody warns you about before perimenopause hits. In...
info_outlineThe Girlfriend Doctor w/ Dr. Anna Cabeca
Grab your Mighty Maca and get cozy. In this episode of The Girlfriend Doctor Podcast, Dr. Anna Cabeca sits down with the very first graduates of her Magic Menopause Hormone Restoration Coaching Certification, Emily, Ann, Amy and Angela. Four women, four completely different paths into menopause, and one shared mission, making sure no woman has to go through this alone. We're talking surgical menopause, the myths that keep women suffering in silence, the postpartum "mini menopause" nobody warns you about, and what it actually takes to feel like yourself again. Key Timestamps 0:00 Welcome...
info_outlineThe Girlfriend Doctor w/ Dr. Anna Cabeca
You leave your doctor's office with "everything looks normal" ringing in your ears, but your body is telling you something else. This week Dr. Anna talks with nurse practitioner Dr. Efrat LaMandre, aka Dr. E, about medical gaslighting, why "you're fine" often means "I ran out of tools," and how to advocate for yourself without burning every bridge with your doctor. You'll learn: The difference between "normal" and "optimal," and why it matters What "pre-disease" is and why most providers aren't equipped for it How to describe your symptoms so your doctor actually listens Why one...
info_outlineThe Girlfriend Doctor w/ Dr. Anna Cabeca
Have you done everything right and still watched the scale refuse to move? I sat down with fitness industry veteran Chalene Johnson, who built her career telling women exactly how to lose weight, and then walked straight into that same wall herself in perimenopause. Her hormone panel came back "dialed in." She was still doing every workout, every macro track, every habit that used to work. The weight stayed anyway, until she found the piece nobody had pointed her toward, the link between cortisol, insulin resistance, and a metabolism that stops cooperating no matter how hard you push. We get...
info_outlineWhat if your diagnosis wasn’t your destiny? What if your genes weren’t your fate—but your choices were?
In this powerful and eye-opening episode, Dr. Anna Cabeca sits down with world-renowned holistic health expert Dr. Fab Mancini to explore the science and hope behind epigenetics, self-healing, and reversing chronic disease. After nearly four decades in natural health, Dr. Fab shares why less than 10% of disease is genetic—and how your daily habits, stress, environment, and mindset determine whether disease-promoting genes are activated or silenced.
Dr. Fab Mancini is an internationally recognized Doctor of Chiropractic, bestselling author of The Power of Self-Healing and Self Health, and former President of Parker University. He has appeared on Dr. Phil, CNN, FOX News, and Univision, and has inspired millions worldwide to reclaim their health and unlock their full potential.
In this conversation, you’ll discover:
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Why your body is designed to heal—and what blocks it
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The truth about epigenetics and activating or reversing disease
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How stress, toxins, and lifestyle choices influence your genes
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Why your diagnosis is not a life sentence
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The #1 mindset shift to reclaim your health and vitality
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How small daily choices can reverse chronic disease pathways
Dr. Fab reminds us that healing doesn’t begin with prescriptions—it begins with awareness, empowerment, and action.
This episode is a must-listen for anyone who wants to take ownership of their health and discover the profound power within their body to heal.
Share this episode with someone who needs hope—and take your next step toward self-healing.
Key Timestamps
00:01 – Why managing symptoms doesn’t create true healing
03:20 – The biggest myth in modern healthcare
04:47 – The body’s innate intelligence and ability to heal
08:11 – Hidden toxins affecting your health today
10:36 – Stress, mental health, and disease activation
12:55 – Dr. Fab’s near-death experience that shaped his mission
15:45 – Regenerating your body, mind, and vitality at any age
25:04 – Why health must become your top priority
29:13 – Epigenetics explained: why genes are not your destiny
31:39 – How simple choices can reverse chronic disease
33:14 – Why your diagnosis is not a life sentence
36:53 – Free tools and resources to support your healing
Memorable Quotes
Dr. Fab Mancini:
“Managing our symptoms has never truly helped the body heal. What really heals us is identifying and addressing the root cause.”
“Less than 10% of chronic disease is genetic. The rest is driven by epigenetics—our lifestyle choices activate or deactivate those genes.”
“Your diagnosis is not a life sentence. No one determines your destiny except you.”
“You can either live in survival, thinking only about your needs—or live in service, supporting others. That’s where the true magic happens.”
“One better choice today can begin moving you away from chronic disease and toward self-healing.”
Dr. Anna Cabeca:
“We are the CEO of our body. Our choices are ours to make.”
“One next right step at a time—every day we get to choose again.”
“We have within us our innate ability to heal and to thrive.”
Connect With Guest: Dr. Fab Mancini
Website: https://drfabmancini.com
Instagram: https://www.instagram.com/drfabmancini
Podcast: The Fab Life
Connect With Dr. Anna Cabeca:
Website: https://dranna.com
Instagram: https://www.instagram.com/thegirlfrienddoctor/
YouTube: https://www.youtube.com/@thegirlfrienddoctor