874 - What Is Berberine & Will It Actually Make You Lose Weight?
Dr. Ruscio Radio, DC: Health, Nutrition and Functional Healthcare
Release Date: 01/15/2024
Dr. Ruscio Radio, DC: Health, Nutrition and Functional Healthcare
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info_outlineYou might have heard the buzz around berberine, often referred to as “nature's Ozempic”.
Berberine is a powerhouse for many things, from reducing inflammation to regulating blood sugar levels.
Tune in to hear which benefits the science supports (and the surprising ones it doesn’t) and get a simple dosing guide.
And if you have any additional questions you would like answered in the future, let me know in the comments!
Watch/Read Next…
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Diets Debunked: Weight Watchers: https://drruscio.com/weight-watchers/
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Genetic Testing for Weight Loss Isn’t Worth it. Here’s what is: https://drruscio.com/genetic-testing-for-weight-loss/
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How to Heal Your Gut Naturally: https://drruscio.com/how-to-heal-your-gut-naturally/
Timestamps
00:00 Intro
01:00 What is berberine?
01:37 Weight loss
02:34 Cholesterol
05:52 Blood sugar
08:47 Gut health
11:15 SIBO
12:53 Berberine dosing guide
Featured Studies
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Biological properties and clinical applications of berberine: https://pubmed.ncbi.nlm.nih.gov/32335802/
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Berberine: Botanical Occurrence, Traditional Uses, Extraction Methods, and Relevance in Cardiovascular, Metabolic, Hepatic, and Renal Disorders: https://pubmed.ncbi.nlm.nih.gov/30186157/
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The Effect of Berberine on Reproduction and Metabolism in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Control Trials: https://pubmed.ncbi.nlm.nih.gov/31915452/
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The effect of berberine supplementation on obesity parameters, inflammation and liver function enzymes: A systematic review and meta-analysis of randomized controlled trials: https://pubmed.ncbi.nlm.nih.gov/32690176/
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The effect of berberine supplementation on lipid profile and obesity indices: An umbrella review of meta-analysis: https://www.sciencedirect.com/science/article/abs/pii/S2213434423000361
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Berberine decreases plasma triglyceride levels and upregulates hepatic TRIB1 in LDLR wild type mice and in LDLR deficient mice: https://pubmed.ncbi.nlm.nih.gov/31666640/
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Berberine decreases cholesterol levels in rats through multiple mechanisms, including inhibition of cholesterol absorption: https://pubmed.ncbi.nlm.nih.gov/25002181/
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Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials: https://pubmed.ncbi.nlm.nih.gov/36941490/
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Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials: https://pubmed.ncbi.nlm.nih.gov/31094214/
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The Effect of Berberine on Metabolic Profiles in Type 2 Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials: https://pubmed.ncbi.nlm.nih.gov/34956436/
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Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials: https://pubmed.ncbi.nlm.nih.gov/37598753/
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Effects of berberine and barberry on selected inflammatory biomarkers in adults: A systematic review and dose-response meta-analysis of randomized clinical trials: https://pubmed.ncbi.nlm.nih.gov/37675930/
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Berberine improves intestinal epithelial tight junctions by upregulating A20 expression in IBS-D mice: https://pubmed.ncbi.nlm.nih.gov/31306972/
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Berberine Enhances Intestinal Mucosal Barrier Function by Promoting Vitamin D Receptor Activity: https://pubmed.ncbi.nlm.nih.gov/37046128/
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Berberine influences multiple diseases by modifying gut microbiota: https://pubmed.ncbi.nlm.nih.gov/37599699/
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Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner: https://pubmed.ncbi.nlm.nih.gov/26700862/
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A Randomized Clinical Trial of Berberine Hydrochloride in Patients with Diarrhea-Predominant Irritable Bowel Syndrome: https://pubmed.ncbi.nlm.nih.gov/26400188/
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Efficacy and safety of berberine in preventing recurrence of colorectal adenomas: A systematic review and meta-analysis: https://pubmed.ncbi.nlm.nih.gov/34509605/
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Berberine and rifaximin effects on small intestinal bacterial overgrowth: Study protocol for an investigator-initiated, double-arm, open-label, randomized clinical trial (BRIEF-SIBO study): https://pubmed.ncbi.nlm.nih.gov/36873985/
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Berberine and health outcomes: An umbrella review: https://pubmed.ncbi.nlm.nih.gov/36999891/
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Bioavailability study of berberine and the enhancing effects of TPGS on intestinal absorption in rats: https://pubmed.ncbi.nlm.nih.gov/21637946/
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Efficacy of berberine in patients with type 2 diabetes mellitus: https://pubmed.ncbi.nlm.nih.gov/18442638/
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*Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.