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One woman's story of getting better - a conversation with Julie Gregory

Evolving Past Alzheimer's

Release Date: 11/15/2017

Our Sense of Smell - Brainwaves of COVID and Alzheimer's with Thom Cleland PhD show art Our Sense of Smell - Brainwaves of COVID and Alzheimer's with Thom Cleland PhD

Evolving Past Alzheimer's

This is a more theoretical episode that gives us some idea about what might be happening with the rhythms of an Alzheimer's or POST-COVID brain.

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Evolving Past Alzheimer's

In this episode, we go deep into the potential benefits of specialized meditation for our immune systems, brain-related proteins, Alzheimer's, cellular energy, and much more. Our guest, Dr Hemal Patel - is a full professor and serves as the Vice-Chair for Research in the Department of Anesthesiology at the University of California, San Diego.

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Lisa's Story - Chap. 2 - Living Well with Alzheimer's  show art Lisa's Story - Chap. 2 - Living Well with Alzheimer's

Evolving Past Alzheimer's

Earlier this year, podcast episode #65 - we spoke to Lisa and her daughters Stacy and Natalie. They told us about how they were Living Well with Alzheimer's and improving using lifestyle and personalized approach. Her cognitive decline had stabilized and seen small, but significant improvements in brain function.  This episode we review some of the elements  that have led to their success

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Evolving Past Alzheimer's

“We’re actually able to change the brain, even in the face of things like Alzheimer’s disease.” This was the statement made by our guest for this show, Dr. Ben Hampstead. Dr. Hampstead is a professor at the Univ of Michigan and leads a lab that is doing several studies using transcranial direct current stimulation for mild cognitive impairment, Alzheimer's, and other forms of cognitive impairment. 

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Your Brain On Sugar  show art Your Brain On Sugar

Evolving Past Alzheimer's

Nikki Gould, a registered dietician at Kemper Cognitive Wellness is also joining us today to talk about what sugar can do to your brain and your overall health and how we can navigate the holidays with this information in mind.

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Working with Trauma in Alzheimer's & Dementia show art Working with Trauma in Alzheimer's & Dementia

Evolving Past Alzheimer's

Trauma can be defined as any event that alters how we process, react to, and recall memories, by overwhelming the individual’s central nervous system. Additionally, trauma is defined as any event in which a person feels helpless and unsafe. It is not only an occurrence that happened in the past; instead, trauma is an event that leaves an imprint upon the body and the brain which persists to the present day.

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Why I'm excited about Aducanumab (Aduhelm)! show art Why I'm excited about Aducanumab (Aduhelm)!

Evolving Past Alzheimer's

Dr. Nate Bergman quickly summarizes the story up the FDA's recent "accelerated approval" of Biogen's - Aducanumab (brand named, Aduhelm). He ends off with surprise about why he is excited about the approval...and it's probably not what you think! A quick, but useful listen.

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Living well with Alzheimer's - Lisa's story of getting back to herself. show art Living well with Alzheimer's - Lisa's story of getting back to herself.

Evolving Past Alzheimer's

This episode is an important listen for anyone with doubts, reservations, or skepticism around a precision, functional medicine approach to the treatment of Alzheimer's disease.

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Does the new Alzheimer's drug Aducanumab mean the end of Alzheimer's? with Marwan Sabbagh, MD. show art Does the new Alzheimer's drug Aducanumab mean the end of Alzheimer's? with Marwan Sabbagh, MD.

Evolving Past Alzheimer's

In this episode, we hear the argument in favor of the new Alzheimer's drug, Aducanumab (Aduhelm).  Dr. Marwan Sabbagh is a clinical and research leader at the Cleveland Clinic's Lou Ruvo Center for Brain Health. He was a doctor that saw patients in one of the trials that led to the FDA's Accelerated (provisional) Approval. 

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People Getting Better- More Trial Results with Drs Ann Hathaway & Deborah Gordon show art People Getting Better- More Trial Results with Drs Ann Hathaway & Deborah Gordon

Evolving Past Alzheimer's

This week we will do almost a Part 2 from the last episode with Drs Dale Bredesen and Kat Toups.  In that episode, we featured recently released results data on MedArchive from a clinical trial in which 84% of 25 patients with early Alzheimer's Disease and Mild Cognitive Impairment improved with a Precision Medicine approach.  

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On the cusp of her 50th birthday Julie Gregory started to experience symptoms of cognitive decline.  Feeling alone and terrified, and given her family history of Alzheimer's, Julie sought to do something. Julie learned that she was an ApoE-4 homozygote -  in other words she has both genetic copies of the ApoE4 gene which increased her chance of developing Alzheimer's by 50% - 90%. This episode discusses Julie's health journey and what she done to improve her cognitive and general health.

Along with a few other people, Julie founded ApoE4.Info Inc. - a crowdsourced website that brings people info in science and self-experimentation for those with one or two copies of the high risk gene for developing Alzheimer's (ie the ApoE4 gene).

Important NOTE: not everyone that is diagnosed with Alzheimer's has copies of the ApoE4 gene.

Julie's Most Effective Strategies for Brain Health

  1. Exercise 60 minutes per day - low and moderate intensities.
  2. "Super clean diet" - no grains, high numbers of natural colors, high vegetables, healthy fats (she focuses on plant fats and less so on the saturated animal fats).  
  3. Reduced cerebral glucose utilization - ketones can create alternate fuel (mild ketosis) you can do this by reducing sugar intake and ingesting MCT oil
  4. Optimizing sleep - blue blocker glasses 3 hours before bed (to ramp up melatonin production)
  5. Meditation - any kind for any amount of time
  6. Impeccable tooth care- coconut oil pulling  (10 minutes per day). Julie uses non-fluoride toothpaste
  7. "Skin Deep Database" by the Environmental Working Group- to find safe skin care products

Minute 22:30 - Discussion about Babesia Duncani, Lyme related infections, chronic microbial infections (ie potential infectious micro-organisms) and how the research seems to suggest that these may lead to some of the proteins (beta amyloid in specific) that we know our causally related to Alzheimer's. Also, Julie tells her story about getting tested and treated for some of these infections.

Minute 32:01 On why talking about Alzheimer's or Pre-Alzheimer's is such a touchy subject and the goal of APOE4.INFO - the crowd-sourced website that Julie and others founded to help those looking for accurate information. They have an active forum and facebook page that you can interact with.  We also discuss the ethical controversy of genetic testing to understand your Alzheimer's risk (spoiler alert: Julie and I are both fans of checking) and the controversy around talking about the view that Alzheimer's is potentially reversible and preventable.

Find out more about Julie's organization to help you understand your risk: apoE4.info