loader from loading.io

One woman's story of getting better - a conversation with Julie Gregory

Evolving Past Alzheimer's

Release Date: 11/15/2017

Why I'm excited about Aducanumab (Aduhelm)! show art Why I'm excited about Aducanumab (Aduhelm)!

Evolving Past Alzheimer's

Dr. Nate Bergman quickly summarizes the story up the FDA's recent "accelerated approval" of Biogen's - Aducanumab (brand named, Aduhelm). He ends off with surprise about why he is excited about the approval...and it's probably not what you think! A quick, but useful listen.

info_outline
Living well with Alzheimer's - Lisa's story of getting back to herself. show art Living well with Alzheimer's - Lisa's story of getting back to herself.

Evolving Past Alzheimer's

This episode is an important listen for anyone with doubts, reservations, or skepticism around a precision, functional medicine approach to the treatment of Alzheimer's disease.

info_outline
Does the new Alzheimer's drug Aducanumab mean the end of Alzheimer's? with Marwan Sabbagh, MD. show art Does the new Alzheimer's drug Aducanumab mean the end of Alzheimer's? with Marwan Sabbagh, MD.

Evolving Past Alzheimer's

In this episode, we hear the argument in favor of the new Alzheimer's drug, Aducanumab (Aduhelm).  Dr. Marwan Sabbagh is a clinical and research leader at the Cleveland Clinic's Lou Ruvo Center for Brain Health. He was a doctor that saw patients in one of the trials that led to the FDA's Accelerated (provisional) Approval. 

info_outline
People Getting Better- More Trial Results with Drs Ann Hathaway & Deborah Gordon show art People Getting Better- More Trial Results with Drs Ann Hathaway & Deborah Gordon

Evolving Past Alzheimer's

This week we will do almost a Part 2 from the last episode with Drs Dale Bredesen and Kat Toups.  In that episode, we featured recently released results data on MedArchive from a clinical trial in which 84% of 25 patients with early Alzheimer's Disease and Mild Cognitive Impairment improved with a Precision Medicine approach.  

info_outline
New Study Results with Drs Kat Toups & Dale Bredesen show art New Study Results with Drs Kat Toups & Dale Bredesen

Evolving Past Alzheimer's

Our guests today are Drs Kat Toups & Dale Bredesen.

info_outline
Being Patient - The Evolution of Data in Alzheimer's & Dementia with Deborah Kan show art Being Patient - The Evolution of Data in Alzheimer's & Dementia with Deborah Kan

Evolving Past Alzheimer's

Deborah Kan is a former executive producer with the Wall Street Journal. In 2017 she founded the website BeingPatient.com, a comprehensive website dedicated to Alzheimer's news, stories, and support.

info_outline
Pushing Back Against Dementia - Chrissy's Journey show art Pushing Back Against Dementia - Chrissy's Journey

Evolving Past Alzheimer's

We are witnessing a sea change in dementia. More people are being diagnosed, earlier and younger. And people are figuring out how to actually fight back against the disease and taking ownership of their condition.

info_outline
A Patient Story: The Heart-Brain Connection & Energy  show art A Patient Story: The Heart-Brain Connection & Energy

Evolving Past Alzheimer's

George suffered a major brain injury as a result of his heart stopping about 4 years ago.  Fortunately, he has successfully recovered from the brain injury and this is the story of how the Mullers did it!

info_outline
Taking Hormones After Menopause - New Data with Felice Gersh MD show art Taking Hormones After Menopause - New Data with Felice Gersh MD

Evolving Past Alzheimer's

We get many questions from listeners and people seeking Alzheimer’s prevention and early intervention about the risks and benefits of hormone therapies, such as estrogen and progesterone.

info_outline
Live Well With Dementia  show art Live Well With Dementia 

Evolving Past Alzheimer's

In this episode, you'll meet the co-founders of Kemper House and Kemper Cognitive Wellness.

info_outline
 
More Episodes

On the cusp of her 50th birthday Julie Gregory started to experience symptoms of cognitive decline.  Feeling alone and terrified, and given her family history of Alzheimer's, Julie sought to do something. Julie learned that she was an ApoE-4 homozygote -  in other words she has both genetic copies of the ApoE4 gene which increased her chance of developing Alzheimer's by 50% - 90%. This episode discusses Julie's health journey and what she done to improve her cognitive and general health.

Along with a few other people, Julie founded ApoE4.Info Inc. - a crowdsourced website that brings people info in science and self-experimentation for those with one or two copies of the high risk gene for developing Alzheimer's (ie the ApoE4 gene).

Important NOTE: not everyone that is diagnosed with Alzheimer's has copies of the ApoE4 gene.

Julie's Most Effective Strategies for Brain Health

  1. Exercise 60 minutes per day - low and moderate intensities.
  2. "Super clean diet" - no grains, high numbers of natural colors, high vegetables, healthy fats (she focuses on plant fats and less so on the saturated animal fats).  
  3. Reduced cerebral glucose utilization - ketones can create alternate fuel (mild ketosis) you can do this by reducing sugar intake and ingesting MCT oil
  4. Optimizing sleep - blue blocker glasses 3 hours before bed (to ramp up melatonin production)
  5. Meditation - any kind for any amount of time
  6. Impeccable tooth care- coconut oil pulling  (10 minutes per day). Julie uses non-fluoride toothpaste
  7. "Skin Deep Database" by the Environmental Working Group- to find safe skin care products

Minute 22:30 - Discussion about Babesia Duncani, Lyme related infections, chronic microbial infections (ie potential infectious micro-organisms) and how the research seems to suggest that these may lead to some of the proteins (beta amyloid in specific) that we know our causally related to Alzheimer's. Also, Julie tells her story about getting tested and treated for some of these infections.

Minute 32:01 On why talking about Alzheimer's or Pre-Alzheimer's is such a touchy subject and the goal of APOE4.INFO - the crowd-sourced website that Julie and others founded to help those looking for accurate information. They have an active forum and facebook page that you can interact with.  We also discuss the ethical controversy of genetic testing to understand your Alzheimer's risk (spoiler alert: Julie and I are both fans of checking) and the controversy around talking about the view that Alzheimer's is potentially reversible and preventable.

Find out more about Julie's organization to help you understand your risk: apoE4.info