Ep 315 The Tox Talks (Chapter 10): Lessons Learned About Letibotulinum Toxin | Dr Konstantin Frank
Release Date: 09/25/2025
Inside Aesthetics
Episode 335 showcases our hosts Dr Jake Sloane & David Segal. In our ‘What’s trending in Aesthetics?’ episodes we discuss popular topics doing the rounds on social media, issues being debated in injector forums or items showcased on the news. We’ll cover controversies, big stories and themes that have got injectors and our industry talking. In Chapter 16 we delve into the key overall trends that we predict will influence the year ahead. We discuss: The shift towards 'slow ageing' (long term planning and smaller but more frequent treatments) The rise of bio-stimulators...
info_outlineInside Aesthetics
Episode 334 hosts Dr Kourosh Tavakoli (Plastic Surgeon from Sydney, Australia) In this episode we discuss the latest trends and innovations in plastic surgery. We cover the rising popularity of GLP-1 weight loss drugs and the significant impact they are having on surgical trends and procedures. We then do a deep dive into the current preferences in breast aesthetics and the continuing evolution in techniques including as implant technology, lipo filling and the use of mesh for 'internal bra' support. We also cover the rare complications of breast implants known colloquially as 'breast implant...
info_outlineInside Aesthetics
Episode 333 hosts Mike Clague (Nurse Injector from Melbourne, Australia) In 'The Tox Talks' episodes we feature expert injectors who have significant experience in using botulinum toxins. These episodes explore our guests experiences using particular brands, the evolution of their injecting techniques and we get special insights into the subtle nuances of getting the best out of toxins. In chapter 11 we talk about Relfydess, a new Botulinum Toxin A manufactured by Galderma. We first re-introduce Mike (previously on episode 276) and his clinical background. We then cover his...
info_outlineInside Aesthetics
Episode 332 hosts Dr Steven Sorr (Naturopathic Doctor from Arizona, USA) Steven joins us in the 31st chapter of our series called ‘The Injector Diaries’. These episodes feature in depth conversations, stories and experiences from injectors around the globe. Each injector brings their own unique take on things and we showcase every level of type of injector, from newbies to masters. We’ll explore how and why they chose to inject, why they favour using certain products, look under the hoods of their clinics and aim to inspire our injector listeners. 00:00 Introduction 01:08 Meet Dr....
info_outlineInside Aesthetics
Episode 331 hosts (Anaesthesiologist from California, USA) & (Dermatologist from Montreal, Canada) Back in September 2025 and were attendance as speakers at the . They took the opportunity to record with two other leading KOL speakers; Bita (previously on Episode 283) & Roni. We first get an understanding of our guests own patient demographics and their recent experiences of dealing with filler anxiety expressed by their patients. We explore the nuances of an effective patient consultations and cover the aspects of winning trust, education and the role of personalised...
info_outlineInside Aesthetics
Episode 330 hosts Dr Felix Bertram (Dermatologist from Zurich, Switzerland) Felix is a successful Dermatologist, serial entrepreneur and has been on the podcast several times to share his business insights. But in this episode we discuss something very different - a very real story about the serious challenges of trying to balance numerous multi-million dollar businesses and the consequences of impending burnout. We talk about Felix's health scare after taking a random biological age test and how he changed everything to overcome this. Our conversation highlights how to recognise when work and...
info_outlineInside Aesthetics
Episode 329 hosts Dr Ferial Fanian (Dermatologist from Paris, France) In our ‘Masterclass Series’ we host global experts to teach us about fillers, bio-stimulators, bio-remodellers, polynucleotides, exosomes and other products. (For toxin insights, check out our other mini-series, ‘The Tox Talks’) In Chapter 11 we go on a deep dive into the science of 'biostimulation' . With collagen stimulation now a seemingly generic term used for many new products launched, we aim to differentiate how these products can be classified and how they actually biostimulate. We also cover some basics of...
info_outlineInside Aesthetics
Episode 328 hosts Alex Thiersch (Attorney & CEO of ). In this extra mid-week podcast episode, Alex discusses the evolution of the med spa industry in the United States, the compliance and regulatory challenges practitioners face, and the importance of business acumen. The conversation also delves into the role of AMSPA in providing resources, education, and community support to med spa owners and practitioners. They touch on the issues of industry self-regulation, advocacy efforts, and the future prospects of the medical aesthetics field. Additionally, Alex highlights the annual Medical...
info_outlineInside Aesthetics
Episode 327 showcases our hosts Dr Jake Sloane & David Segal. In our ‘What’s trending in Aesthetics?’ episodes we discuss popular topics doing the rounds on social media, issues being debated in injector forums or items showcased on the news. We’ll cover controversies, big stories and themes that have got injectors and our industry talking. In Chapter 15 our hosts Dr Jake and David explore three key trends: 1) The controversial use of artificial intelligence in aesthetic advertising & clinical practice 2) Laser Clinics hiring PwC to sell their United Kingdom and North...
info_outlineInside Aesthetics
Episode 326 hosts Sydney Slubik (Registered Nurse from Edmonton, Canada & the winner of our IA X ICCE Competition) Sydney joins us in the 30th chapter of our series called ‘The Injector Diaries’. These episodes feature in depth conversations, stories and experiences from injectors around the globe. Each injector brings their own unique take on things and we showcase every level of type of injector, from newbies to masters. We’ll explore how and why they chose to inject, why they favour using certain products, look under the hoods of their clinics and aim to inspire our injector...
info_outlineEpisode 315 hosts Dr Konstantin Frank (Aesthetic Doctor from Regensberg, Germany)
In 'The Tox Talks' episodes we feature expert injectors who have significant experience in using botulinum toxins. These episodes explore our guests experiences using particular brands, the evolution of their injecting techniques and we get special insights into the subtle nuances of getting the best out of toxins.
In Chapter 10 we talk about Letybo (made by Hugel, Korea) and how to get the best out of it. We discuss the unique properties of Letibotulinum toxin including its precision and reduced diffusion, which make it particularly effective for areas where precision can't be compromised.
Konstantin shares his expertise on optimal injection techniques, addressing common challenges and how practitioners can achieve the best results. The conversation also delves into the importance of combining treatments for comprehensive aesthetic outcomes and the business implications of using different toxins.
00:00 Introduction
00:52 Conference Vibes and Guest Introduction
02:17 Discussion on Toxins and Techniques
03:03 Konstantin's Background and Expertise
04:35 Exploring Toxins: Techniques and Challenges
08:40 The Science Behind Toxins
11:50 Regulatory Challenges and Innovations 1
7:21 Advanced Injection Techniques
27:37 Touch-ups and Dosage Adjustments
28:49 Setting Patient Expectations 2
29:39 Exploring Toxin Reversal Methods
31:27 Understanding Toxin Duration and Onset
36:44 Discussing Toxin Resistance
38:55 Communicating Changes to Patients
45:59 Combining Treatments for Better Results
49:30 Business Considerations in Aesthetics
52:08 Conclusion