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E.194 The Peptide Playbook: A Conversation with Dr. Rob Frankel

Bathroom Diaries w. Dr Sofia Din

Release Date: 01/22/2026

E.198 The Pause: A Modern Guide to Longevity, Skin Health & Proactive Aging show art E.198 The Pause: A Modern Guide to Longevity, Skin Health & Proactive Aging

Bathroom Diaries w. Dr Sofia Din

Unlock the new science of aging gracefully — and powerfully. In this episode, Dr. Din dives deep into the Pause — menopause, andropause, the metabolic slowdown, and how modern medicine is transforming the way we navigate longevity. From GLP-1 agonists to glow peptides, IV nutrient infusions, anti-aging injectables, skin tightening, and proactive self-care at every decade of life… this conversation explains exactly why aging today is nothing like aging 20 years ago. Whether you're in your 20s exploring prevention, in your 40s navigating hormone transitions, or in your 60s reclaiming...

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In this clip from Bathroom Diaries, Dr. Sofia Din and Dr. Rob Frankel break down one of the most common mistakes people make with peptides: thinking one peptide can fix everything. Using a simple and hilarious analogy — “asking for one peptide is like going to a tire shop and buying just one tire” — they explain why peptides work best as a system, not a single quick fix. If you're curious about how peptides actually work, which combinations make sense, and why personalized protocols matter, this highlight is a must-watch. 📌 In this clip: • Why “one peptide” doesn’t work •...

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Join us in this inspiring episode as Dr. Sofia Din, physician and longevity expert, shares powerful insights about healthy aging, beauty from within, menopause, the gut-brain-skin connection, and what she believes were the most impactful longevity breakthroughs of 2025. We explore how genetics shape beauty, why preserving your best self is possible with the right tools, and how perimenopause and menopause affect the entire body—not just hormones. Dr. Sophia also reveals her annual gratitude list for innovations that truly help women thrive through every stage of life.  Whether you’re...

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The Future of Longevity, Conscious Aging & Medical-Grade Health Optimization In this episode, we dive deep into the evolving world of longevity medicine, proactive health management, and conscious aging. Our conversation explores how modern medicine is shifting away from sickness management and toward preventive, personalized, and data-driven health optimization. We discuss topics like: Why aging should be treated as a renewable system The difference between health management vs. sickness management Hormonal pauses, menopause, and andropause Medical-grade IV “oil changes” and nutrient...

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E.194 The Peptide Playbook: A Conversation with Dr. Rob Frankel show art E.194 The Peptide Playbook: A Conversation with Dr. Rob Frankel

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In this new episode of Bathroom Diaries, I sit down with Dr. Rob Frankel, emergency physician, anti-aging specialist, and host of the Modern Man Podcast, for an honest, science-forward conversation about one of the most talked-about tools in modern longevity: peptides. But this isn’t hype. This episode goes beyond TikTok trends and biohacking buzzwords. We unpack what peptides actually are, how they work inside the body, who should (and should not) be using them, and why precision and medical integrity matter more than ever in this space. Dr. Frankel explains peptides as “text messages”...

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Join Dr. Din from Juvanni for a powerful, unfiltered 1-hour deep dive into longevity, anti-aging, menopause, GLP-1 agonists, hair restoration, skin health, and the science behind beauty. This episode of Bathroom Diaries blends medical science, storytelling, humor, and real-world clinical insights—all designed to help you understand your body, your hormones, and your aging process with clarity and confidence.   00:00 Introduction and welcome from Dr. Din 01:15 Longevity talk and what’s coming in 2025 03:40 The year of GLP-1 agonists 06:52 Wegovy, Ozempic, Mounjaro, Zepbound explained...

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Because aging — and metabolic health — should be intentional, not accidental. © 2009–2023 by Sofia Din MD & Juvanni Med Spa.   00:00 The Shift: Geriatrics to Longevity 03:30 Chapter 1: Genetic Code & The "Pre-programmed Pause" 07:00 Chapter 2: The Body as a Test Tube: Intuition vs. Data 10:45 Chapter 3: AI Concierge & Smart Toilets 14:30 Chapter 4: The Medical-Grade "Oil Change" (IV Therapy) 18:15 Chapter 5: Stem Cells & Exosomes: Why Quality Matters 22:00 Chapter 6: Lifting Men and Women out of "The Pause" 25:30 Summary: The Future of Healthspan & Social...

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Welcome to Bathroom Diaries — a real and honest conversation between Dr. Sophia and Dr. Kerline, two physicians passionate about women’s health, longevity, and aesthetic medicine. In this episode, we explore how beauty, health, and wellness connect — from the gut-brain relationship to skin aging, hormonal balance, menopause and andropause, and the real meaning of medical-grade skincare. Discover how lifestyle, nutrition, and modern longevity medicine can help you age beautifully and stay vibrant at every stage of life. 💫

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More Episodes

In this new episode of Bathroom Diaries, I sit down with Dr. Rob Frankel, emergency physician, anti-aging specialist, and host of the Modern Man Podcast, for an honest, science-forward conversation about one of the most talked-about tools in modern longevity: peptides.

But this isn’t hype.

This episode goes beyond TikTok trends and biohacking buzzwords. We unpack what peptides actually are, how they work inside the body, who should (and should not) be using them, and why precision and medical integrity matter more than ever in this space.

Dr. Frankel explains peptides as “text messages” to your cells, signals that enhance your body’s own intelligence rather than override it. We explore where peptide therapy shows real promise, where caution is essential, and how innovation can coexist with responsibility.

In this episode, we talk about:

* What peptides really do at a cellular level
* The difference between enhancement vs. “sledgehammer” medicine
* GLP-1s, Tesamorelin, BPC-157, NAD, GHK Copper & more
* Peptides for metabolism, recovery, cognition, skin & longevity
* Why not every body is a candidate
* The danger of self-prescribing from the internet
* How peptides fit into a whole-body, intelligent aging strategy

This conversation is for anyone curious about longevity, aesthetics, metabolic health, and the future of personalized medicine, without the smoke and mirrors.

Because aging well isn’t about chasing trends.
It’s about understanding your biology and guiding it wisely.

 

00:00 Introduction: Peptides, Longevity & Medical Integrity

02:05 Meet Dr. Rob Frankel (ER Physician & Anti-Aging Specialist)

04:30 What Peptides Actually Are (Simple Biology Explained)

07:10 Peptides as “Text Messages” to Your Cells

10:15 Peptides vs Traditional Medicine (Signal vs Sledgehammer)

13:40 GLP-1 Peptides & Metabolic Health

17:30 FDA Approval, Safety & the Gray Areas of Peptides

21:10 Tesamorelin: Visceral Fat, Growth Hormone & Longevity

25:10 CJC & Growth Hormone Signaling

28:20 BPC-157 & TB-500 for Recovery and Inflammation

 32:00 Cognitive Peptides: BDNF, C-Max & Brain Performance

 36:20 Peptide Dosing, Monitoring & Blood Work

39:30 NAD Explained: Energy, Krebs Cycle & Cellular Aging

 44:00 NAD Safety, Cancer Risk & Proper Cycling

 47:10 GHK Copper Peptides for Skin, Hair & Aesthetics

51:20 Do Peptides Enhance Botox, Fillers & Laser Results?

 54:10 Cost of Peptide Therapy & Cycling Strategy

56:40 Who Should NOT Use Peptides

59:20 Peptides, Menopause, Andropause & Hormonal Health

01:03:10 The Future of Personalized & Systems Medicine

01:05:10 Rapid Fire: Most Overhyped & Underrated Peptides

01:07:30 Final Thoughts: Aging Intelligently