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E.194 The Peptide Playbook: A Conversation with Dr. Rob Frankel
01/22/2026
E.194 The Peptide Playbook: A Conversation with Dr. Rob Frankel
In this new episode of Bathroom Diaries, I sit down with Dr. Rob Frankel, emergency physician, anti-aging specialist, and host of the Modern Man Podcast, for an honest, science-forward conversation about one of the most talked-about tools in modern longevity: peptides. But this isn’t hype. This episode goes beyond TikTok trends and biohacking buzzwords. We unpack what peptides actually are, how they work inside the body, who should (and should not) be using them, and why precision and medical integrity matter more than ever in this space. Dr. Frankel explains peptides as “text messages” to your cells, signals that enhance your body’s own intelligence rather than override it. We explore where peptide therapy shows real promise, where caution is essential, and how innovation can coexist with responsibility. In this episode, we talk about: * What peptides really do at a cellular level * The difference between enhancement vs. “sledgehammer” medicine * GLP-1s, Tesamorelin, BPC-157, NAD, GHK Copper & more * Peptides for metabolism, recovery, cognition, skin & longevity * Why not every body is a candidate * The danger of self-prescribing from the internet * How peptides fit into a whole-body, intelligent aging strategy This conversation is for anyone curious about longevity, aesthetics, metabolic health, and the future of personalized medicine, without the smoke and mirrors. Because aging well isn’t about chasing trends. It’s about understanding your biology and guiding it wisely. Introduction: Peptides, Longevity & Medical Integrity Meet Dr. Rob Frankel (ER Physician & Anti-Aging Specialist) What Peptides Actually Are (Simple Biology Explained) Peptides as “Text Messages” to Your Cells Peptides vs Traditional Medicine (Signal vs Sledgehammer) GLP-1 Peptides & Metabolic Health FDA Approval, Safety & the Gray Areas of Peptides Tesamorelin: Visceral Fat, Growth Hormone & Longevity CJC & Growth Hormone Signaling BPC-157 & TB-500 for Recovery and Inflammation Cognitive Peptides: BDNF, C-Max & Brain Performance Peptide Dosing, Monitoring & Blood Work NAD Explained: Energy, Krebs Cycle & Cellular Aging NAD Safety, Cancer Risk & Proper Cycling GHK Copper Peptides for Skin, Hair & Aesthetics Do Peptides Enhance Botox, Fillers & Laser Results? Cost of Peptide Therapy & Cycling Strategy Who Should NOT Use Peptides Peptides, Menopause, Andropause & Hormonal Health The Future of Personalized & Systems Medicine Rapid Fire: Most Overhyped & Underrated Peptides Final Thoughts: Aging Intelligently
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