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Quick Hits: The Power of Your Genes and What They Can Tell You About Your Health, Ability to Lose Weight, Detox and More!

The Hormone Solution Podcast with Karen Martel

Release Date: 05/20/2025

Progesterone HRT Sensitivity & PMDD – When “The Chill Pill” Isn’t So Chill

The Hormone Solution Podcast with Karen Martel

Are you or someone you know grappling with unexpected mood swings or unexplained anxiety? Could progesterone, often touted as "nature's chill pill," be the surprising culprit? This episode dives deep into the perplexing world of progesterone sensitivity and its profound impact on mental health. Why do some women experience the exact opposite of calm when exposed to this hormone? Join us as we challenge conventional hormone treatments and uncover the hidden effects of progesterone on the brain. How can trauma amplify hormone sensitivity, particularly during the luteal phase? What role do...

From Neck Skin to Miracle Molecules: The Anti-Aging Skin Care Secrets No One Talks About with Amitay Eschel

The Hormone Solution Podcast with Karen Martel

Curious about the truths behind anti-aging skincare? What if you could unlock the secrets to timeless skin without falling for industry hype? Join us as Amitay Eschel, CEO of Young Goose, exposes the insincere promises of the skincare world and shares genuine insights into cellular rejuvenation. Are you wondering how societal pressures shape our pursuit of youth? What are the real roles of nutrition, peptides, and physical health in maintaining a youthful appearance? Discover the importance of informed skincare decisions, and explore the fine line between reversing the appearance of aging...

Quick Hits: Menopause as a Brain Event: Rethinking the Change with Dr. Fiona Lovely

The Hormone Solution Podcast with Karen Martel

Dr. Fiona Lovely is a women's health expert with specialties in functional medicine, functional neurology and restorative endocrinology. She has lectured on the topics of women's health, hormone balance and brain function extensively. She is the creator and host of a popular long-running podcast on the passage of peri-menopause called Not Your Mother's Menopause. A million + people around the world have downloaded the podcast, listening in to learn about the physical, mental and spiritual journey of menopause. Her mission is to share info to empower women and pull back the curtain to reveal...

STOP Using Ozempic (GLP1's) the Wrong Way: Top Tips for Crushing It on Weight Loss Peptides with Karen Martel and Jessica Brennan

The Hormone Solution Podcast with Karen Martel

Jessica Brennan, started in the fitness industry 10 years ago as a fitness instructor and personal trainer, realized early on that achieving health goals went beyond physical activity. This realization led Jessica to pursue certifications in nutrition, hormone specialist, and gut health specialist, aiming to address health challenges holistically. Working closely with Karen at Hormone Solutions, Jessica is dedicated to sharing her expertise with women globally. Her areas of expertise include bodybuilding, women’s hormone health, personalized nutrition, peptide therapy, and chronic illness...

The Hidden Cause of Fatigue, Burnout, and Brain Fog (From Toxic Load to Breast Implant Illness) with Michele Scarlet

The Hormone Solution Podcast with Karen Martel

Have you ever wondered if your constant fatigue, burnout, or brain fog might be more than just a busy schedule? Could hidden environmental toxins be affecting your health? Join us as we dive deep into these questions with Michele Scarlet, a board-certified functional medicine practitioner. In this episode, Michele shares her personal journey with breast implant illness and how it led her to explore the impact of toxic beauty standards. What are the hidden dangers of breast implants, and how do they relate to chronic inflammation and other health issues? Michele’s story sheds light on the...

Starting HRT More Than 10 Years After Menopause: What the Science Really Says

The Hormone Solution Podcast with Karen Martel

Are you or someone you know experiencing menopause symptoms even a decade later? Could modern hormone replacement therapy be the solution you've been searching for? Discover how this podcast episode uncovers the transformative potential of HRT, debunking myths and misconceptions along the way. Have you ever wondered about the impact of estrogen loss on your bone health and overall well-being? Could transdermal estradiol and bioidentical progesterone offer safer alternatives? Dive into the critical role of timely hormone therapy in maintaining health and reducing risks, even for those well...

Quick Hits: Are You a Grey Area Drinker? Find Out!

The Hormone Solution Podcast with Karen Martel

In today's Quick Hits blast from the past: Sarah Rusbatch is a certified Women's Health and Wellbeing Coach, an accredited Grey Area Drinking Coach and a Key-Note speaker sharing her journey to Sobriety and the impact of alcohol on mental health to global audiences. After developing what she describes as 'a dysfunctional relationship with alcohol', Sarah made the decision to remove alcohol from her life in early 2019 and has never looked back. She now works with women across the globe, guiding them from feeling lost, stuck and out of control (something she fully understands herself), to a...

Women & Microdosing: The Mushroom That Rewires Your Brain

The Hormone Solution Podcast with Karen Martel

Curious about the potential of psilocybin for women's health? What if the secret to breaking free from harmful habits lies in a psychedelic compound? Join us as we delve into the intriguing world of psilocybin and its transformative possibilities. Can psilocybin offer a fresh perspective on mental health challenges and hormonal shifts? Is it time to rethink our relationship with alcohol? Discover why legal substances might not be as safe as we believe. How can psilocybin help in overcoming emotional and physical challenges? Our guest, Jennifer Chesak, shares her personal journey and insights...

Progesterone, Patches & Night Sweats: Your Top HRT Questions Answered with The Meno Besties

The Hormone Solution Podcast with Karen Martel

This episode is a juicy one, my friends! I joined my incredible meno bestie, Zora Benhamou, for a listener Q&A on her podcast Hack My Age—and we’re tackling all things hormone replacement therapy (HRT). Are you ready to unlock the secrets of hormone health? Have you ever wondered about the real impact of progesterone or the mysteries of DHEA? We're exploring controversial claims and surprising findings about progesterone production in women. What role does HRT play in managing menopause symptoms like night sweats? Could bioidentical hormone therapy be the answer you've been seeking...

Quick Hits: Frustration to Fulfillment: Overcoming Female Sexual Dysfunction with HRT with Deb Mathews

The Hormone Solution Podcast with Karen Martel

In today's Quick Hits blast from the past: Dr. Deb Matthews also known as, The Happy Hormones Doctor, is a best-selling author, international speaker, educator, wife and mom of four boys. After suffering for years from fatigue and irritability due to hormone imbalances, her quest to resolve her personal health led her to change everything about her practice of medicine. She has been featured on national podcasts, radio, and broadcast shows, including NBC, ABC, CBS, and FOX.Dr. Matthews and Karen take a deep dive into women's sexual dysfunction. In this episode Why is this an important topic...

More Episodes

Welcome to Quick Hits: Blasts from The Past. Join Karen as she explores her podcast archives, offering you short, impactful excerpts from standout episodes. In just 15 minutes, you'll experience the essence of past conversations, packed with valuable insights and memorable moments from our guests. If you want to dive deeper, you'll find links to the full episodes in the show notes below.

Listen to the full episode.

What if your weight loss struggles aren’t about discipline or calories—but about how your genes process inflammation, carbs, and toxins?

In this episode, I’m joined by functional health expert and former malpractice attorney Sam, who breaks down how your genetic pathways affect everything from weight loss resistance to detox capacity, hormone metabolism, and food sensitivities.

Forget obsessing over one red MTHFR gene—this episode will teach you how to see the whole genetic picture, so you can personalize your diet, detox, and supplement strategy for real results.

What We Cover:

Why some women gain more fat the more they exercise (yep, it’s genetic!)
The Muffin Test: A surprising clue that your inflammation genes are out of balance
Inflammation, water retention, and the hidden reason for overnight weight gain
The concept of hormonal toxic fat and how poor detoxification can trap weight
The myth of “willpower” and why toxic load may be sabotaging your best efforts
How mineral deficiencies + heavy metals mess with your enzyme function
What your copy number genes say about your carb tolerance and ideal diet
Why your fat cells are like toxic closets—and how to open them safely

Why It Matters:

Your genes are not a death sentence—they're a user manual. Whether you struggle with weight loss, detox overload, mood swings, or midlife mystery symptoms, understanding your genetic code is the first step to healing.

This episode will empower you to stop blaming your body—and start working with it instead.

Visit Dr. Sam Shay's website here.

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