loader from loading.io

From the archive: Philosophers on psychedelics

Many Minds

Release Date: 07/17/2026

From the archive: Varieties of childhood show art From the archive: Varieties of childhood

Many Minds

Hi friends! We're taking a bit of a summer pause. We'll be back soon—in the meanwhile, enjoy this listener favorite from our archives! ----- [originally aired July 10, 2025] Childhood is a special time, a strange time. Children are adored and catered to—they're given their own menus and bedrooms. They're considered delicate and precious, and so we cushion them from every imaginable risk. Kids are encouraged to play, of course—but very often it's under the watchful eye of anxious adults. This, anyway, is how childhood looks in much of the United States today. But is this the way childhood...

info_outline
From the archive: Philosophers on psychedelics show art From the archive: Philosophers on psychedelics

Many Minds

Hi friends! We're taking a bit of a summer pause. We will be back soon—in the meanwhile, enjoy this listener favorite from our archives! ----- [originally aired May 14, 2025] Some call it the "psychedelic renaissance." In the last decade or so, interest in psychedelic drugs has surged—and not just among Silicon Valley types and psychiatrists and neuroscientists. It's also surged among a stereotypically soberer crowd: academic philosophers. The reasons are clear. With their varied and sometimes transformative effects, psychedelics raise ethical questions, epistemological questions,...

info_outline
The origins of Darwin's ideas show art The origins of Darwin's ideas

Many Minds

No discipline, no sphere of intellectual life, has been untouched by the work of Charles Darwin. He died in 1882 but his ideas are very much alive; they're now central to how we understand the natural world, the human mind, non-human minds, plants, biogeography, morality and emotion, culture, language, and more. But where did his ideas come from? How did they grow out of his travels, his social circle, his hobbies, his particular cast of mind?  My guest today is . Janet is Professor Emerita at Harvard University in the department of the History of Science. She is perhaps best known for...

info_outline
The sparkling deep show art The sparkling deep

Many Minds

It’s tempting to see bioluminescence as an oddity, one of those rare eccentricities of life on earth. And, on land, maybe that’s true. But our planet is mostly water, and out in the open ocean bioluminescence is utterly commonplace. Creatures of all shapes and sorts sparkle and glow, glitter and pulse. But what are these displays for? Why did they evolve? How did light become the currency of the deep?   My guest today is . Sönke is a Distinguished Professor of Biology at Duke University, where he and his research group study the visual ecology of the ocean. He’s the author of...

info_outline
Is Man the Hunter just a myth? show art Is Man the Hunter just a myth?

Many Minds

There's a story about of our past that you know well. It goes like this: At some point earlier in human evolution, we started to hunt. Men in particular—perhaps channeling some deep-seated aggressive impulses—began to seek out big game. This new food source, this bonanza of calories, was what allowed our brains to expand. It changed our bodies and our societies and sent our species off on a whole new track. In short, Man the Hunter made us human. This story—told in different versions, with different points of emphasis—has circulated for decades. It's been debunked and revived, rejected...

info_outline
Babies, dogs, and the riddles of word learning show art Babies, dogs, and the riddles of word learning

Many Minds

It's kind of astonishing, really, that kids ever learn words. Each one poses a little riddle. Does this sound string refer to a person? A category of things? Or maybe some other feature of the blooming, buzzing world? And yet word learning happens. In fact, we now know it begins earlier in infancy than we realized. And we now know, further, that dogs (or at least some dogs) understand words as well. So how does this happen? What do babies and dogs really know about words? And how might we go about figuring this all out? My guests today are and Dr. Claudia Fugazza. Elika is an Associate...

info_outline
The inner life of the hand show art The inner life of the hand

Many Minds

Newton saw in the human hand proof of the divine; Darwin saw a key to our species' success. Many others, too, have described the hand in hyperbolic terms, as a paragon of design, a cornerstone of human uniqueness, an engine of our achievements. But what makes the human hand so powerful? Is it the proportions of the fingers? Is it the opposability of the thumb? Or, could it be none of this? Could it be that the real power of our hands lies—not in the physical design—but elsewhere, out of sight?  My guest today is . Matt is Professor of Cognitive Neuroscience at Birkbeck, University of...

info_outline
From the archive: The cuttlefish and its coat of many colors show art From the archive: The cuttlefish and its coat of many colors

Many Minds

Hi friends! We're skipping a beat to take care of some spring housekeeping tasks. We will be back in May! In the meanwhile, enjoy this listener favorite from our archives! ----- [originally aired April 30, 2025] We humans have a hard time becoming invisible. For better or worse, we're basically stuck with the skin and body we have; we’re pretty fixed in our color, our shape, our overall appearance. And so we're fascinated by creatures that aren't—creatures that morph to meet the moment, that can functionally disappear, that can shape-shift on a dime. And no creatures are more skilled,...

info_outline
Illuminating cave art show art Illuminating cave art

Many Minds

Deep in our past, in the dark depths of caves, our ancestors did something strange and beautiful. Working by firelight, some doodled little designs. Others made hand stencils. Some saw a bulge of rock, or a crack in the wall, and thought to turn it into a horse or a bison. Why did they make this art? What did it mean to them? Who were these artists? These questions are old—very old—but thanks to new methods and new interpretive frameworks, archaeologists are beginning to see them in a new light.  My guest today is . Izzy is an archaeologist at Aarhus University in Denmark,...

info_outline
What can AI teach us about the mind? show art What can AI teach us about the mind?

Many Minds

Everyone is talking about AI these days. Often these conversations are about how AI might upend education, or work, or social life, or maybe civilization itself. But among cognitive scientists and psychologists the conversation inevitably drifts toward other questions. What does this latest generation of AI tell us about the human mind? Is it putting old ideas and theories to rest? Is it ushering in new ones? Will AI—in other words—also upend cognitive science? My guests today are and . Mike is a Professor of Psychology at Stanford University, where focuses on language learning and...

info_outline
 
More Episodes

Hi friends! We're taking a bit of a summer pause. We will be back soon—in the meanwhile, enjoy this listener favorite from our archives!

-----

[originally aired May 14, 2025]

Some call it the "psychedelic renaissance." In the last decade or so, interest in psychedelic drugs has surged—and not just among Silicon Valley types and psychiatrists and neuroscientists. It's also surged among a stereotypically soberer crowd: academic philosophers. The reasons are clear. With their varied and sometimes transformative effects, psychedelics raise ethical questions, epistemological questions, metaphysical questions, questions about the nature of experience and the nature of the mind.

My guest today is Dr. Chris Letheby. Chris is a philosopher of cognitive science at the University of Western Australia and the author of the 2021 book, Philosophy of Psychedelics.

Here, Chris and I talk about the so-called classic psychedelics—LSD, psilocybin, ayahuasca, and others—and how interest in them has gone through three distinct waves. We discuss the effects that these substances seem to have, in particular their capacity to treat certain psychiatric conditions and their tendency to induce "mystical-like" experiences. We consider the idea that psychedelics might serve as agents of moral enhancement. And we dig into the psychological and neural mechanisms by which psychedelics seem to have their diverse—and often salutary—effects. Along the way, we talk about ontological shock, comforting delusions, brain plasticity, unselfing, microdosing, placebo effects and adverse effects, physicalism and idealism, the REBUS model, environmental virtues, plant consciousness, meditation, and much more.

Maybe this is obvious but this episode is not just for the seasoned psychonauts out there. Whatever your personal experience with these substances, they offer a distinctive window into the mind—a new way of grappling with big questions. Perhaps this much is also obvious but we're not encouraging or endorsing the use of psychedelics here—just offering a little fuel for your intellectual fires!

Alright friends, on to my conversation w/ Dr. Chris Letheby. Enjoy!

 

A transcript of this episode is available here

 

Notes and links

4:00 – For a brief historical overview of research into psychedelics, see this paper.

8:30 – For work by an early trailblazer in the philosophy of psychedelics, see Thomas Metzinger’s Being No One.

12:30 – For our earlier episode on the psychology and philosophy of visual illusions, see here. 

18:00 – For a history of the concept of “set and setting,” see here.

19:00 – A 2024 review of “adverse events” in classic psychedelics.

26:00 – A blog post on the history of the term “psychedelic.”

27:00 – A recent review and meta-analysis of the use of psychedelic therapy for depressive symptoms.

31:00 – On mystical experience see Walter Stace’s classic work, Mysticism and Philosophy. On the measurement of mystical-type experiences, see, e.g., Walter Pahnke’s paper here.

36:00 – On the idea of “psychoplastogens,” see here.

39:00 – See our earlier audio essay on placebo effects.

41:00 – For the study using Ritalin as an active placebo, see here. 

44:00 – Michael Pollan’s book on psychedelics is here.

48:00 – On the idea of “idealism,” see here.

50:30 – For the 2021 study on psychedelics’ capacity to alter metaphysical beliefs, see here.

54:00 – For Dr. Letheby and collaborators’ paper about the “mysticism wars,” see here.

1:02:00 – For a popular article on the possibility that psychedelics reduce fear of death, see here.

1:03:00 – For Dr. Letheby’s paper on psychedelics and the fear of death, see here.

1:11:00 – The phrase “comforting delusion” comes from an article by Michael Pollan.

1:15:00 – For the “REBUS model,” see here.

1:20:00 – On the idea that psychedelics could serve as agents of moral enhancement, see the paper by Brian Earp here.

1:21:00 – For Dr. Letheby’s paper on psychedelics and environmental virtues, see here. For his paper on psychedelics and forgiveness, see here.

1:23:00 – On the subfield of “virtue ethics,” see here. On the virtue of “living in place,” see the paper by Nin Kirkham here.

1:28:00 – For the New Yorker article, by Matthew Hutson, on how psychedelics led him to see trees as smart, see here. For the study, led by Sandeep Nayak, on psychedelics leading people to expand their attributions of consciousness, see here.

1:32:00 – For a first paper by Dr. Letheby on the comparison between meditation and psychedelics, see here.

 

Recommendations

Psychedelic Experience, Aidan Lyon

Varieties of Psychedelic Experience, Robert Masters & Jean Houston

The Antipodes of the Mind, Benny Shanon

 

Many Minds is a project of the Diverse Intelligences Summer Institute, which is made possible by a generous grant from the John Templeton Foundation to Indiana University. The show is hosted and produced by Kensy Cooperrider, with help from Assistant Producer Urte Laukaityte and with creative support from DISI Directors Erica Cartmill and Jacob Foster. Our artwork is by Ben OldroydOur transcripts are created by Sarah Dopierala.

Subscribe to Many Minds on Apple, Stitcher, Spotify, Pocket Casts, Google Play, or wherever you listen to podcasts. You can also now subscribe to the Many Minds newsletter here!

We welcome your comments, questions, and suggestions. Feel free to email us at: manymindspodcast@gmail.com. 

For updates about the show, visit our website or follow us on Twitter (@ManyMindsPod) or Bluesky (@manymindspod.bsky.social).