316: Science is Just Catching Up to What Bodybuilders Have Known for Years Ft Jim Stoppani
Release Date: 10/13/2025
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Have you ever noticed the latest fitness research just confirms what old-school bodybuilders have been doing for decades?
I sat down with Dr. Jim Stoppani, a scientist who studies molecular physiology and bodybuilding applications. We talked about training methods that science is finally confirming, like how partial repetitions focused on the stretch are highly effective for muscle building. We discussed why full range of motion is not always necessary for hypertrophy and how top bodybuilders intuitively figured this out. We also cover periodization, the problem with oversimplification of training research, and the absolute minimal effective training dose to gain muscle. Plus, Dr. Jim shares his non-negotiable rule for daily movement, regardless of how often you work out.
Key Takeaways
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Things like progressive overload, super high protein diets, and creatine were once considered "bro science" but are now confirmed by research.
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Applicable advice requires understanding both the lab (molecular aspect) and the gym (surface level results).
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For hypertrophy (muscle growth), focusing on the stretch or initiation (first part) of the movement, often via "long length partials," may be more critical than achieving a full range of motion or peak contraction.
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Full extension during exercises like the bench press can shift tension away from the target muscle (pecs) to the shoulders and triceps, which is not ideal for the bodybuilder focused on hypertrophy.
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Both high reps and heavy weight/low reps are effective and should be used in a periodized program, as high reps may instigate different physiological benefits, like angiogenesis (capillary production).
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You can build muscle with as little as one set twice a week, but consistency and changing up the stress on the muscle (periodization) are key for continued progress.
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Creatine is recommended not only for muscle and strength but also for brain function and health. It is particularly recommended for young athletes in contact sports as it may help protect from and recover from concussions.
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Regardless of gym workouts, daily movement is critical. The rule suggests that for every 30 minutes of consecutive sitting, you should get up and move for 60 seconds.
Resources
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Jim Stoppani´s website: https://jymsupplementscience.com/
Jim Stoppani´s Instagram: @jimstoppani
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Host Nate Palmer The founder of The Million Dollar Body and Author of "The Million Dollar Body Method", Nate has been in the industry of coaching over 15 years and has worked with over 1000 clients personally.
· Nate Palmer’s Website: https://milliondollarbodylabs.com/
· "The Million Dollar Body Method" by Nate Palmer: http://getnatesbook.com
· Lean Energy Stack: https://milliondollarbodylabs.com/pages/lean
· @_milliondollarbody (IG) https://www.instagram.com/_milliondollarbody