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E286 - GLP-1 Agonists in Psychiatry: Beyond Weight Loss with Dr. Roger McIntyre

NEI Podcast

Release Date: 07/15/2026

E292 - Re-release: Wired for Creativity? The Bipolar-Genius Connection with Dr. Tiffany Greenwood show art E292 - Re-release: Wired for Creativity? The Bipolar-Genius Connection with Dr. Tiffany Greenwood

NEI Podcast

Originally released in 2022, this episode of The PsychopharmaStahlogy Show features Drs. Andrew Cutler and Stephen Stahl in conversation with Dr. Tiffany Greenwood on the genetic and trait-based links between bipolar disorder and creativity. They explore how temperament, personality, and cognitive style may occupy the space between madness and genius, the role of dopamine, evolutionary explanations for why bipolar risk persists, and why stabilizing mood doesn't have to mean losing creativity.   Tiffany A. Greenwood, PhD, is an Associate Professor in the Department of Psychiatry...

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E291 - Re-release: Recognizing and Treating Anhedonia with Dr. Vladimir Maletic show art E291 - Re-release: Recognizing and Treating Anhedonia with Dr. Vladimir Maletic

NEI Podcast

Originally released in 2024, this episode features the late Dr. Vladimir Maletic in conversation with Drs. Andy Cutler and Stephen Stahl about the clinical significance and neurobiology of anhedonia. They discuss its different dimensions, how it differs from emotional blunting, its relationship to functioning and treatment response, and practical approaches to assessment and treatment. The episode highlights why recovery from depression requires restoring interest, motivation, and pleasure—not simply reducing negative symptoms.  Vladimir Maletic, MD, MS, was a clinical professor of...

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E290 - ADHD and Substance Use Disorders: Treatment Challenges with Dr. Timothy Wilens show art E290 - ADHD and Substance Use Disorders: Treatment Challenges with Dr. Timothy Wilens

NEI Podcast

In this episode, Dr. Andy Cutler speaks with Dr. Tim Wilens about the complex relationship between attention-deficit/hyperactivity disorder (ADHD) and substance use disorders. They discuss how to distinguish ADHD from substance-related cognitive symptoms, determine when co-occurring conditions should be treated concurrently, and select appropriate ADHD medications based on the substance involved. Dr. Wilens also examines stimulant misuse and diversion, the role of nonstimulants, what is known about centanafadine’s abuse potential, and practical approaches to monitoring treatment without...

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E289 - Recognizing and Managing the Biggest Mistakes in Psychopharmacology with Dr. Thomas Schwartz show art E289 - Recognizing and Managing the Biggest Mistakes in Psychopharmacology with Dr. Thomas Schwartz

NEI Podcast

Originally released in 2021, this episode features Dr. Thomas Schwartz discussing common mistakes in psychopharmacology and how psychiatric clinicians can recognize and manage them. He explores diagnostic uncertainty, medication dosing, informed consent and monitoring, and rational versus irrational polypharmacy. He also considers how clinicians can reassess inherited diagnoses, learn from prescribing errors, and preserve the therapeutic relationship when mistakes occur.   Thomas L. Schwartz, MD, is a Distinguished Teaching Professor at Norton College of Medicine, SUNY Upstate...

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E288 - PsychopharmaPearls: Kratom—What Clinicians Need to Know with Dr. William Sauvé show art E288 - PsychopharmaPearls: Kratom—What Clinicians Need to Know with Dr. William Sauvé

NEI Podcast

In this episode of PsychopharmaPearls, Dr. Andy Cutler and Dr. Will Sauvé discuss what clinicians need to know about kratom. They review why patients use it, signs of misuse, dependence, or withdrawal, and key pharmacologic and safety concerns. The conversation also offers practical guidance for discussing kratom use and incorporating it into treatment planning.  William Sauvé, MD, is a board-certified psychiatrist and Chief Medical Officer at Osmind. He has extensive experience in interventional psychiatry, including TMS and esketamine, and previously served for 11 years as an...

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E287 - Deprescribing Practices in Psychiatry with Drs. Stephen Stahl and Jeffrey Strawn show art E287 - Deprescribing Practices in Psychiatry with Drs. Stephen Stahl and Jeffrey Strawn

NEI Podcast

In this episode, Dr. Andy Cutler is joined by Drs. Stephen Stahl and Jeffrey Strawn to discuss deprescribing practices in psychiatry. They explore why deprescribing is an essential clinical skill, how to determine whether a patient still needs a medication, dose, or combination, and how to approach tapering in a way that balances relapse prevention, withdrawal risk, and patient-centered care. The conversation also covers practical considerations for deprescribing antidepressants, antipsychotics, benzodiazepines, and sedative-hypnotics, with attention to common pitfalls and strategies for...

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E286 - GLP-1 Agonists in Psychiatry: Beyond Weight Loss with Dr. Roger McIntyre show art E286 - GLP-1 Agonists in Psychiatry: Beyond Weight Loss with Dr. Roger McIntyre

NEI Podcast

In this episode, Dr. Andy Cutler is joined by Dr. Roger McIntyre to discuss GLP-1 receptor agonists in psychiatry and why these medications may be relevant beyond weight loss. They explore the emerging role of GLP-1s in metabolic psychiatry, including potential connections with mood disorders, cognition, reward pathways, cardiometabolic health, and psychiatric medication-associated weight gain. Dr. McIntyre also discusses what psychiatric providers should know now, where the evidence is still evolving, and what future research is needed before GLP-1 or incretin-based therapies could be...

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E285 - Re-release: Eating Disorders, Nutrition, and the Brain with Dr. Cynthia Bulik show art E285 - Re-release: Eating Disorders, Nutrition, and the Brain with Dr. Cynthia Bulik

NEI Podcast

Originally released in June 2023, this episode features Dr. Cynthia Bulik in a discussion of eating disorders, nutrition, and the brain. The conversation explores anorexia nervosa, bulimia nervosa, binge eating disorder, ARFID, common misconceptions about eating disorders, and the evolving understanding of how biology, genetics, and environment shape risk, diagnosis, and recovery.   Cynthia Bulik, PhD, FAED, is a Distinguished Professor of Eating Disorders in the Department of Psychiatry at the University of North Carolina at Chapel Hill and Professor of Nutrition in the...

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E284 - Nutritional Interventions in Psychiatry: Hype vs. Evidence with Dr. Bhagwan Bahroo show art E284 - Nutritional Interventions in Psychiatry: Hype vs. Evidence with Dr. Bhagwan Bahroo

NEI Podcast

In this episode, Dr. Andy Cutler talks with Dr. Bhagwan Bahroo about nutritional interventions in psychiatry, including diet, supplements, metabolic health, inflammation, and the gut-brain axis. They explore where the evidence is strongest, where hype outpaces the data, and how clinicians can discuss nutritional strategies as adjunctive tools without losing focus on core treatments.  Bhagwan A. Bahroo, MD, DLFAPA, is a board-certified psychiatrist in adult, addiction, and forensic psychiatry and an Assistant Professor at the Uniformed Services University of the Health...

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E283 - PsychopharmaPearls: When Akathisia Looks Like Agitation with Dr. Leslie Citrome show art E283 - PsychopharmaPearls: When Akathisia Looks Like Agitation with Dr. Leslie Citrome

NEI Podcast

In this episode of PsychopharmaPearls, Dr. Andy Cutler talks with Dr. Leslie Citrome about akathisia, a common but often misdiagnosed antipsychotic side effect that can look like agitation, anxiety, irritability, or worsening psychiatric symptoms. They discuss how to recognize akathisia in clinical practice, distinguish it from true agitation, identify key timing and symptom clues, and avoid common treatment...

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More Episodes

In this episode, Dr. Andy Cutler is joined by Dr. Roger McIntyre to discuss GLP-1 receptor agonists in psychiatry and why these medications may be relevant beyond weight loss. They explore the emerging role of GLP-1s in metabolic psychiatry, including potential connections with mood disorders, cognition, reward pathways, cardiometabolic health, and psychiatric medication-associated weight gain. Dr. McIntyre also discusses what psychiatric providers should know now, where the evidence is still evolving, and what future research is needed before GLP-1 or incretin-based therapies could be considered part of psychiatric treatment. 

Roger S. McIntyre, MD, FRCPC, is Professor of Psychiatry and Pharmacology at the University of Toronto and Head of the Mood Disorders Psychopharmacology Unit at the University Health Network in Toronto. He is an internationally recognized expert in mood disorders and psychopharmacology, with published scholarship and presentations exploring the relevance of GLP-1 receptor agonists to psychiatry. 

Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. 

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