Optimizing life for maximum fulfillment | Bill Perkins (#237 rebroadcast)
Release Date: 11/25/2024
Building & Changing Habits | James Clear (#183 rebroadcast)
The Peter Attia Drive
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The Peter Attia Drive
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Optimizing life for maximum fulfillment | Bill Perkins (#237 rebroadcast)
The Peter Attia Drive
Bill Perkins is one of the world’s most successful hedge fund managers and entrepreneurs, and the author of the bestseller, Die With Zero. In this episode, Bill unpacks the Die With Zero philosophy which challenges conventional thinking related to the balance between health, wealth, and time—the three variables important for fulfillment. Bill makes the case that we should strive for maximum net fulfillment rather than net worth (or even health). He argues that we need to optimize our life to have memorable experiences before it’s too late and that most people are over-saving and...
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The Peter Attia Drive
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The Peter Attia Drive
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The Peter Attia Drive
Eric Ravussin is a world-renowned expert on obesity, metabolism, and aging whose pioneering research has shaped much of what we understand today about energy balance and caloric restriction. In this episode, Eric shares insights from his cutting-edge work on energy expenditure—a critical factor in understanding how our bodies regulate weight and appetite. He discusses methods for measuring energy output, energy balance, food intake, and appetite regulation, and explores key studies on macronutrient manipulation. Eric then delves into the CALERIE study on caloric restriction, highlighting...
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#323 - CRISPR and the future of gene editing: scientific advances, genetic therapies, disease treatment potential, and ethical considerations | Feng Zhang, Ph.D.
The Peter Attia Drive
Feng Zhang, a professor of neuroscience at MIT and a pioneering figure in gene editing, joins Peter to discuss his groundbreaking work in CRISPR technology, as well as his early contributions to optogenetics. In this episode, they explore the origins of CRISPR and the revolutionary advancements that have transformed the field of gene editing. Feng delves into the practical applications of CRISPR for treating genetic diseases, the importance of delivery methods, and the current successes and challenges in targeting cells specific tissues such as those in the liver and eye. He also covers the...
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#322 - Bone health for life: building strong bones, preventing age-related loss, and reversing osteoporosis with evidence-based exercise | Belinda Beck, Ph.D.
The Peter Attia Drive
Belinda Beck, founder of The Bone Clinic and a leading authority on exercise physiology and bone health, delves into the science of osteoporosis, bone density, and the lifelong importance of maintaining skeletal health. In this episode, she explains how the foundation for strong bones is established during childhood, offering valuable advice for parents on optimizing bone health for their kids. She also explores how bone remodeling occurs throughout life, driven by activity, nutrition, and hormones. Belinda highlights the power of resistance training in improving bone strength, even for...
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Bill Perkins is one of the world’s most successful hedge fund managers and entrepreneurs, and the author of the bestseller, Die With Zero. In this episode, Bill unpacks the Die With Zero philosophy which challenges conventional thinking related to the balance between health, wealth, and time—the three variables important for fulfillment. Bill makes the case that we should strive for maximum net fulfillment rather than net worth (or even health). He argues that we need to optimize our life to have memorable experiences before it’s too late and that most people are over-saving and under-living. Bill also explains how one can apply the principles in Die With Zero to break out of “autopilot” and optimize their life to achieve maximum net fulfillment.
We discuss:
- Bill’s upbringing, background, and first job on Wall Street [2:45];
- A missed experience and feeling of regret that shaped Bill’s thinking [13:45];
- Thinking in terms of time, and the relationship between money, time, and health [16:30];
- Solving for net fulfillment and allocating your time based on the seasons of life [26:45];
- How Bill thinks about risk, opportunity costs, and the difference between fear and risk tolerance [35:00];
- Optimizing for fulfillment, finding purpose outside of work, and more [41:15];
- Thinking about the order of experiences you want to have based on seasons of life [49:30];
- Bill’s unique perspective on philanthropy and a more impactful way to give money away [54:15];
- Applying the principles in ‘Die With Zero’ to maximize fulfillment [1:03:30];
- How to break out of living life on autopilot [1:13:45];
- When should your net worth peak? [1:17:30];
- Taking calculated risks [1:21:00];
- Bill shares a lesson from his incredible birthday [1:24:45];
- How Bill’s philosophy has evolved since writing Die With Zero [1:33:30]; and
- More.
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