Release Date: 09/19/2023
This week we will discuss M-RNA vaccines. Our guest is Thomas VanCott, PhD. Thomas VanCott is currently the Chief Scientific Officer for Combined Therapeutics, a Boston based biotech company developing targeted mRNA therapies. Prior to this he served as the Chief Technology and Strategy Officer for Catalent Cell & Gene Therapy, a global CDMO manufacturing viral vectors for gene and cell therapies as wells as plasmid DNA & mRNA platforms based in Baltimore, MD. He was responsible for strategically enhancing CMC services to meet the market demand of increasingly...info_outline Medically Fragile in a Pandemic
This week we will discuss how important it is to continue masking and keeping away from crowds as a chronically ill or immunocompromised person. Our guest today is Veronica Hanway. Immunocompromised individuals are not optimally protected by COVID-19 vaccines and potentially require additional preventive interventions to mitigate the risk of severe COVID-19. Veronica, a Latina mother and first generation Geography PhD student in her second year, is 35 years old and has had a lifetime of chronic migraines. With her first migraine at just three years old, she is no stranger to...info_outline Sick Sinus Syndrome
This week we will be talking about Sick Sinus Syndrome (SSS) with Audrey Brown. Sick sinus syndrome (SSS) is a disease in which the heart's natural pacemaker located in the upper right heart chamber (right atrium) becomes damaged and is no longer able to generate normal heartbeats at the normal rate. It may be a result of other medical conditions that damage the sinoatrial node (SA node) over time or may be a result of certain medicines. This can result in heartbeats that are too slow, too fast — or heartbeats that alternate between slow and fast. Audrey is 35 years old and...info_outline Staying Healthy as a Vet
This week we are talking once again with Dan "Dry Dock" Shockley on "Staying Healthy as a Veteran" For Veteran's Day this year we are featuring Dan because even though he has been dealt a hard blow with a hereditary colon cancer gene he is not letting that slow him down one bit! As a matter of fact he is thriving and advocating for others around the globe as a hereditary colon cancer ambassador! Here is some more about Dan: Dan Dry Dock Shockley, retired U.S. Navy veteran; Operation Desert Storm; Enduring and Iraqi Freedom veteran and 9 hereditary colon cancer...info_outline Total Knee Replacement Surgery
On today’s show, we are talking about knee replacement surgery with Dawn Richardson, a friend I met in my last couple of years in the Army. Dawn is a retired Navy Captain, former restaurant manager, and former Bed and Breakfast owner who is delighted to say she's now retired and finds fulfillment in her volunteer activities and personal pursuits. About 4% of people 50 and older have knee replacements. At age 80, that number is above 10%. The average age is 65 and more women than men have knee replacements. Three facts we were surprised to hear after speaking with...info_outline Cerbebral Palsy
Cerebral palsy is a group of disorders that affect movement and muscle tone or posture. It's caused by damage that occurs to the immature brain as it develops, most often before birth. Our guest today is Zain Bando, a Chicago area, 21-year-old college student and is studying journalism at the University of Illinois at Urbana-Champaign as a junior. He hopes to pursue a career in broadcasting after graduation and currently resides in Downers Grove, IL with his family.info_outline Leprosy Resurgence
This week, we address the reemergence of leprosy, a disease rarely seen until now, with particular attention to the warning by New York University physician Marc K. Siegel. While the United States generally reports only 150 to 250 leprosy cases yearly, globally, 2 to 3 million people grapple with leprosy-related disabilities. Siegel emphasizes the risk in certain US cities, such as Los Angeles, where unsanitary conditions among the homeless population create fertile ground for diseases like leprosy to thrive. Leprosy, caused by Mycobacterium leprae, can spread more easily in overcrowded,...info_outline Ai in Medicine
This week we discuss the application of Artificial Intelligence (AI) in medicine is revolutionizing healthcare, contributing to improved outcomes, more efficient processes, and reduced costs. Here are some key benefits: Enhanced Diagnostics: AI algorithms, especially those based on deep learning, can analyze complex medical data like X-rays, MRIs, CT scans, and genomics with a high degree of accuracy. They can detect patterns and anomalies that may be invisible to the human eye, or interpret large volumes of data quickly, leading to early and more accurate diagnoses. Personalized...info_outline Chronic Illness & Mental Health
This week we will discuss mental health impacts from living with a chronic illness with our guest, Christy Amos (aka Christi Winstead) Christy Amos is a compassionate and resilient individual who has made it her mission to help others navigate the challenges of living with chronic illnesses. With a Master's degree in Counseling, she has acquired a deep understanding of the emotional and psychological impact that chronic conditions can have on individuals and their loved ones. Despite facing her own health battles, Christy's determination and empathy have driven her to become a patient...info_outline Children Eye Safety
This week we will discuss Eye Safety for children. Eye injuries affect about 2.4 million people every year. Household products cause more than 125,000 serious eye injuries. Hospital emergency rooms treat nearly 23,000 victims of eye injuries from sports. Toys and home playground equipment cause more than 11,000 injuries to young eyes. Below are tips for preventing injury to your child’s eyes. Here are some tips for eye safety for children: Avoid sharp, broken toys and objects. Wear sport goggles and sunglasses. Do not play around lawn mowing and fireworks. Avoid...info_outline
This week we will discuss Metabolic Systems with our guest, Francis Fessler.
A certified personal trainer and conditioning coach for the last 25 years, Francis Fessler has built a career by designing programs and coaching professional and amateur athletes, celebrities, business professionals, parents and children to achieve their wellness and fitness goals. Throughout his time in the health and wellness world he evaluated, tried and tested countless ‘diet and nutrition plans’ and could not find one that had consistent results for both women and men- so he built one. Francis created F2 Wellness and the highly successful F2 Weight Loss Program for not only his clients, but for anyone looking for a simple, successful and sustainable weight loss program.
Have you ever experienced tiredness in your muscles while working out and you couldn’t continue exercising after a certain point? Have you wondered what can make you lift heavier weights or run longer than you can today? If you have, understanding the mechanism of the body's energy system can help you find answers to these questions.
Three metabolic pathways generate the energy required to perform an exercise: the phosphagen pathway, the glycolytic pathway, and the oxidative pathway, together known as the energy systems. Although your body is always using all three simultaneously, depending on the intensity and duration of the exercise, your body will choose from which pathway it will use the largest percentage of its energy.
As you may know, all energy used by our bodies is generated from the breakdown of food and drink. The three macronutrients are protein, carbohydrate, and fat. Those are metabolized to create adenosine triphosphate, which is the source of fuel for all body processes, including muscle contraction.
Unfortunately, the supply of readily available ATP is very limited. It means our bodies constantly have to produce the substance; otherwise, muscle contraction would stop. This re-synthesis of ATP is done by the three energy systems.
The first 10 to 20 seconds of high-intensity physical activity is fueled by the “ATP-CP,” also known as the phosphagen energy system. Once the available ATP is used up, which occurs in a few seconds, a molecule called phosphocreatine is used to re-form ATP in the muscle. This energy system operates very quickly and can bring the highest output of the three systems. However, it is limited by the availability of creatine phosphate, which is usually consumed within 15 seconds.
Your body can eventually refill these stores when you rest. This is why this system is most active for athletes who engage in short bouts of very intense, explosive movement, such as a the 50-meter dash or powerlifting. This is also the reason we can sprint at full speed for only a few seconds or lift maximum loads only 1-2 times before requiring rest or a decrease in exercise intensity using another metabolic pathway.
The second pathway, the glycolytic pathway, is the primary energy system used for exercise lasting from 15 seconds to three minutes. People running an 800-meter event, for example, use this pathway the most. This energy system uses the glucose stored in the muscle, broken down primarily from carbohydrates, to form ATP. The benefit of this pathway is that it kicks in quickly, but it doesn’t make very much energy; it can only supply a maximum of about three minutes of energy. This pathway is responsible for the buildup of lactic acid in our muscles, which contributes to fatigue.
For exercise lasting longer than three minutes, the oxidative pathway is used. Unlike the others, this energy system requires oxygen. The increase in respiratory rate meets the oxygen demand during physical activity. The oxidative system is slow, but is also the most efficient. Using fat as its primary energy substrate, it produces enough ATP to sustain longer duration activities, but only at submaximal exercise output. It means fat is the predominant fuel source used during low to moderate-intensity activity, like biking or jogging long distances.
Now you are more knowledgeable on how your body relies on each of these systems working together to meet the energy demands needed for activities of daily living and exercise.
The system your body will use primarily depends on the type of activities you mostly engage in. The more you train in that particular type of exercise, the better your body adapts to being able to efficiently use that energy system.
For example, individuals who have trained in powerlifting can store more phosphocreatine and ATP than a marathon runner or sedentary individual. On the other hand, endurance-trained individuals have better ventilation ability, maximizing oxygen availability for the oxidative pathway. At the end of the day, consistency is key. If you want to excel at a particular type of exercise, just keep doing it and in time, your body will adapt. (Credits: US Army)